(FRAYM-shift myoo-TAY-shun)
An insertion or deletion involving a number of base pairs that is not a multiple of three, which consequently disrupts the triplet reading frame of a DNA sequence. Such mutations usually lead to the creation of a premature termination (stop) codon, and result in a truncated (shorter-than-normal) protein product.
Pronunciation of dictionary term "frameshift mutation"
Frameshift Mutation