The Medicinal Chemistry SR analyzes, synthesizes small molecule agents
Medicinal Chemistry Shared
Resource Director CHING_SHIH CHEN, PhD, professor of Medicinal
Chemistry, of Internal Medicine, and
of Urology, with colleagues
DASHEN WANG, PhD, and
SAMUEL KULP, PhD, both
research scientists in the College of
The Medicinal Chemistry Shared
Resource (MCSR) integrates synthetic
and process chemistry, instrumental
analysis, molecular pharmacology
and other disciplines to provide
medicinal chemistry support to
investigators at the OSUCCC –
James and other academic and
Services include the following:
• Consultation and general
medicinal chemistry. The MCSR
can determine the chemical
stability, commercial sources, and
purity of commercial chemical
agents. Nuclear magnetic
resonance and mass spectrometric
analyses are used to
determine the identity or purity
of chemical agents. For agents in tablet form, the MCSR can
isolate the active pharmaceutical
ingredient (API) with high purity.
• Custom synthesis. The MCSR
can synthesize agents that are
unavailable from commercial
sources after determining that
synthesis is feasible.
• Lead optimization. MCSR will
identify strategies for structurally
optimizing promising lead agents.
For more information about
the Medicinal Chemistry Shared
Resource call 614-688-4008, or send
an email to firstname.lastname@example.org.
FULL SERVICE BREAST CARE UNDER ONE ROOF
New OSUCCC – James Comprehensive Breast Center Opens Its Doors
The new JamesCare Comprehensive
Breast Center, located near The James Cancer Hospital and the research laboratories of Ohio State's
Comprehensive Cancer Center, began welcoming patients in mid-January. The four-story, multidisciplinary center combines all facets of breast care in one location, including annual mammograms, complete diagnostic services, comprehensive breast-cancer treatment, access to clinical trials, reconstructive breast surgery, medical nutrition services, survivorship support, risk counseling, financial counseling, a library and resource center, a meditation room and private and semi-private waiting areas.
The center also houses Hope's Boutique, a shop that offers a full range of products and services
designed to help women look and feel their best during and after
cancer treatment. The front of the new boutique is a public shopping area, while the back offers privacy and assistance with bra and
MEDICAL CENTER, THE JAMES TO BENEFIT FROM $100 MILLION GIFT
Ohio State University alumnus and Board of Trustees Chair Leslie Wexner, along with the Limited Brands Foundation, are investing $100 million his alma mater.
The majority of the gift—the largest in Ohio State's history—will be allocated to the Medical Center and the James Cancer Hospital and Solove Research Institute, with additional gifts to the Wexner Center for the Arts and other areas within the University.
"During the past several decades, Les Wexner's vision, guidance, engagement and generosity have shaped Ohio State in myriad and lasting ways," says University President E. Gordon Gee. "This latest gift is nothing short of trans-formational. It affirms the direction and growing excellence of our programs and underscores the role that this land-grant institution plays in assuring that talented young people can realize their educational aspirations, make their mark, and do good in the world."
EXCEPTIONAL CANCER RESEARCH FROM PATIENT TO POPULATIONS
More than 700 faculty, staff and students attended this year's OSUCCC – James 13th Annual Scientific Meeting held in February at the University's Ohio
Union. The central purpose of the cancer program's Scientific Meeting is to foster research collaborations that may lead to new studies and possible break-throughs. This year's meeting carried the theme "Exceptional Cancer Research From Patient to Populations," and it included 268 research posters and four speakers from outside Ohio State.