UNRAVELING PHYTOCHEMICAL QUANDARIES
The Nutrient and Phytochemical Analytic Shared Resource
Nutrient and Phytochemical Analytic Shared Resource Director Steven J. Schwartz, PhD, (standing), associate researcher Abby Monnin, MPH, and associate director
Ken M. Riedl, PhD.
The Nutrient and Phytochemical Analytic Shared Resource (NPASR) provides the OSUCCC – James and other investigators with expert bioanalytical method development and quantitative analysis of phytonutrients and their metabolites. Director Steven J. Schwartz, PhD, professor and Carl E. Haas Endowed Chair in the College of Food, Agriculture and Environmental Science, Department of Food Science and Technology, is a member of the OSUCCC – James Molecular Carcinogenesis and Chemoprevention Program. He also directs the Center for Advanced Functional Foods Research and Entrepreneurship.
Associate Director Ken M. Riedl, PhD, an analytical chemist and research scientist, operates three HPLC-MS platforms, each with unique capabilities for identifying and quantifying phytochemicals and their metabolites. His collaborative work spans disciplines from horticulture to nutrition and clinical research.
THE NPASR PROVIDES:
- Expert development of bioanalytical methods and quantitative analysis of nutrients and phytochemicals in foodstuffs and their metabolites in biological samples from both human clinical trials and animal model investigations.
- Particular expertise in evaluating the bioavailability, metabolism and physiological significance of carotenoids, isothiocyanates and isoflavones.
- Development of analytical methods for a Good Laboratory Practice environment.
- An enhanced understanding of the role of dietary compounds in cancer prevention and control.
For more information about the Nutrient and Phytochemical Analytic Shared Resources, call 614-292-4069.
THE NEW JAMES CANCER HOSPITAL AND SOLOVE RESEARCH INSTITUTE
Growing to meet demands for cancer services
ABOVE Artist's rendering of the new Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, scheduled to open in 2014.
Bottom: The Department of Radiation Oncology will be located on the second floor of the new Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, which is expected to open in 2014.
Demand for cancer care is growing, and expected to continue with a projected increase in new cancer cases nationally of 45 percent - from 1.6 million in 2010 to 2.3 million by 2030.
- This rise includes an expected 67 percent increase in cancer incidence among adults 65 years and older due to a growing aging population, and a 99
percent increase among minorities due to aging and growth in minority populations.
- In the state of Ohio, cancer incidence is expected to rise 20 percent by 2030. Increases are expected particularly for melanoma and cancers of the thyroid, liver, pancreas and breast.
- Currently, The James is operating beyond capacity for inpatient and many outpatient services.
The new James Cancer Hospital will ease the burden of cancer.
The new James Cancer Hospital and Solove Research Institute will ease this rising burden of cancer through a larger, state-of-the-art hospital that fosters compassionate care and collaborative, transformational research.
- The new hospital will expand capacity to 276 beds, up from today's 210 beds.
- The new hospital will provide a calming setting designed to promote patient recovery and wellness while integrating research and education.
- The new hospital will offer an environment that inspires and enhances collaboration among OSUCCC - James researchers, who bring ideas and expertise from 11 of Ohio State's 14 colleges.
- The new hospital will help attract and retain leading cancer investigators, talented young minds and the best doctors.
- The new hospital will help revolutionize cancer care and prevention through P4 medicine. (See "A Quiet Evolution" in this issue.)
CONFERENCE CALENDAR
10TH INTERNATIONAL
SKIN CARCINOGENESIS CONFERENCE
June 21-24, 2012
FOCUS: The conference covers squamous cell carcinoma, basal cell carcinoma and melanoma. It will feature the most recent advances in our understanding of the biological, cellular and molecular changes that occur during skin tumor development. It will also explore topics such as the skin as a model system for other tumors, stem cells in skin carcinogenesis and molecular-targeted therapies.
PELOTONIA '11 Raises a Record $13.1 Million
Pelotonia '11 riders and donors raised a record $13,108,639 for cancer research at the OSUCCC - James, a 68-percent increase over the 2010 fundraising total of $7.8 million.
From Aug. 19-21, 4,986 riders from 38 states and four countries rode up to 180 miles on one of four routes during the annual grassroots bicycle tour that was started in 2009. The three-year fundraising total is approximately $25.47 million.
Every dollar raised by riders, virtual riders and donors is invested in research initiatives at the OSUCCC - James, a distinction made possible by Pelotonia's generous funding partners: Limited Brands Foundation; Huntington Bank; Richard and Peggy Santulli; American Electric Power Foundation; Nationwide Insurance; and Cardinal Health Foundation. Pelotonia also benefits from in-kind donations made by numerous locally and nationally based companies, and from the services of some 1,700 volunteers who helped out in 2011.
Pelotonia dollars support research projects that address all aspects of cancer, from diagnosis and treatment to psychosocial issues and prevention. Funds are also used to recruit and retain outstanding cancer researchers to Ohio State and to purchase sophisticated equipment that helps the more than 270 scientists at the OSUCCC - James conduct their research. Details are available online.
Pelotonia 2012 is scheduled for Aug. 10-12. To register, visit http://www.pelotonia.org/.
OSUCCC - James Repeats as a Leapfrog 'Top Hospital'
For the third consecutive year and fourth time in five years, the OSUCCC - James has been named among the safest and most effective hospitals in the country by the Leapfrog Group, a national coalition of public and private purchasers of employee health coverage who collectively work to improve healthcare quality..
The James is among 65 hospitals from a field of almost 1,200 to be named 2011 Leapfrog Top Hospitals based on a rating system that provides an up-to-the-minute assessment of a hospital's quality and safety. A complete list of 2011 Leapfrog Top Hospitals can be viewed at www.leapfroggroup.org. The Leapfrog Group is a consortium of about 150 Fortune 500 companies that pay for healthcare needs of an estimated 34 million Americans.