The ultimate solution to beating cancer would be to avoid it altogether. We can do that to a large degree through lifestyle changes, by minimizing environmental risks and through research that enables us to devise evidence-based interventions.
MICHAEL A. CALIGIURI, MD
OFFICER, JAMES CANCER
HOSPITAL AND SOLOVE
THE OHIO STATE
UNIVERSITY, JOHN L.
FOUNDATION CHAIR IN
At The Ohio State University Comprehensive Cancer Center – James Cancer Hospital and Solove Research Institute (OSUCCC – James), we have a strong group of cancer prevention and control investigators who are developing innovative ways to help more people guard against primary and recurrent cancer.
"The Power of Prevention" in this issue of Frontiers highlights some of our efforts to halt the progression of precancerous lesions in the mouth, prevent or slow prostate-cancer recurrence, and reduce obesity and cancer risk through diet and lifestyle changes.
Of course, people can still develop cancer even when they do all they can to reduce their risk, so we must keep searching for more effective therapies and surgical procedures to help patients overcome their illness and regain an acceptable quality of life – especially when cancer occurs in anatomic sites that are difficult to treat, such as bone.
This issue's cover story, titled "Saving Life And Limb," details complex surgeries performed at the OSUCCC – James by one of the most skilled sarcoma teams in the nation, a team that regularly accepts supremely difficult cases.
You can also read in this issue about our collaborative work with in silico drug design, a discipline that uses computers and computation to discover and optimize targeted anticancer agents, sometimes atom by atom.
As science and technology advance, so do our approaches to preventing and treating cancer. This new issue of Frontiers offers a glimpse of how progress against cancer is unfolding at Ohio State. I think you will find it interesting…and hopeful.