Need to Know 2013 


The Clinical Trials Office (CTO) provides centralized administration of all clinical trials conducted within The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James). The office ensures that clinical trials conducted at the OSUCCC – James are methodologically sound, expedient and cost effective. It currently oversees more than 250 acting and pending trials.
    The office specializes in protocol implementation and coordination, data and regulatory management, negotiating clinical trial agreements and developing clinical trial budgets, internal auditing, and clinical trial education.

The CTO assists investigators in the design of well-constructed clinical trials that have good accrual potential and do not overlap with existing trials.  This assistance includes:

  • Review emerging issues related to new robotics techniques
  • Define patient populations that can benefit from robotic surgery
  • Describe the potential benefits of robotic surgery over open surgery




Designed to transform a three-part mission to achieve one goal

    Patient care, education and research describe the three-part mission of any academic medical center. However, The Ohio State University Comprehensive Cancer Center – James Cancer Hospital and Solove Research Institute combines these to achieve one goal: create a cancer-free world.

    All three mission areas have been tightly integrated into the design of the new James Cancer Hospital and Solove Research Institute, which is targeted to open in 2014.

    A translational-research laboratory is located on each patient-care floor of the new hospital, with wet and dry labs on alternating floors. Wet labs will be equipped for cancer molecular genetics research. Dry labs will provide space where informatics and computational scientists, for example, can analyze genomics and other data.

    The labs will educate, also. Each has a glass front. Patients can look in; researchers can look out. Patients for whom research is an abstract activity will see it under way in their own environment, perhaps instilling greater hope. Researchers who are often isolated from patients will see the consequences of human malignancy, underscoring the importance of their work and strengthening their sense of purpose.

    “These laboratories will also enhance our tissue-banking capacity, which is fundamental to our precision cancer medicine program,” says David E. Schuller, MD, vice president for medical center expansion and outreach. “Ohio State’s cancer program has more than 30 years of tissue-banking experience, and we want to take advantage of that to develop a robust biorepository mechanism.”

    Each floor of the new hospital will have three care-team education centers. Here, teams of faculty, fellows, residents, medical and nursing students will meet to discuss the care of the patients in their respective patient-care neighborhoods. These rooms will be equipped to support educational activities.

    These new spaces will also support Ohio State’s new medical-school curriculum, which calls for first-year students to be involved in patient care. “We will also encourage them to be involved in research,” Schuller says. “To have research activities in patient-care areas should facilitate that interaction.”

    This architectural integration of the three mission areas should increase research productivity, enhance education and lead to more effective care as the cancer program continues its quest to create a cancer-free world.


Michael A. Caligiuri, MD, director of The Ohio State University Comprehensive Cancer Center and CEO of the James Cancer Hospital and Solove Research Institute (OSUCCC – James), is one of five scientists elected by members of the American Association for Cancer Research to serve on the AACR Board of Directors for the 2013 to 2016 term.

The American Association for Cancer Research (AACR) is the world’s first and largest professional organization dedicated to high-quality, innovative cancer research. The organization fosters the exchange of knowledge and new ideas among cancer researchers, provides training opportunities for the next generation of cancer researchers and increases public understanding of cancer.

AACR membership includes more than 34,000 laboratory, translational and clinical researchers, population scientists, other healthcare professionals, and cancer advocates residing in more than 90 countries. The AACR annually convenes more than 20 conferences and educational workshops, the largest of which is the AACR Annual Meeting with more than 17,000 attendees.

Caligiuri holds the John L. Marakas Nationwide Insurance Enterprise Foundation chair in cancer research at Ohio State. He is a professor in the Department of Molecular Virology, Immunology and Medical Genetics, and in the Department of Internal Medicine at Ohio State, and he was chairperson for the AACR Annual Meeting Program Committee in 2009.


Cancer patients seeking to connect with others facing similar challenges can join a new social media network called CancerConnect that allows them and their caregivers to share information, inspiration, hope and support.

The OSUCCC – James has partnered with OMNI Health Media to launch The James CancerConnect to bring together cancer patients, caregivers and others in a welcoming and informative online community.

The free site—which offers participants the opportunity to read informational materials and communicate with others—is open to anyone who registers with a user name and password. Members of The James CancerConnect community are invited to participate in more than 60 disease-specific, online national communities for individuals with similar interests at

Cancer-specific groups are available—as well as groups focused on caregiving, health and wellness, clinical trials, insurance, nutrition and survivorship— to provide support for those affected by cancer.

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