Frontiers

Of Note Winter 2014 

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GRANTS

DENIS GUTTRIDGE, PhD, professor of Medicine and member of the OSUCCC – James Molecular Biology and Cancer Genetics Program, has received a four-year, $1.4 million grant (CA180057) from the National Cancer Institute (NCI) entitled Muscle Stem Cells and Cancer Cachexia. The study explores the inability of muscle stem cells to repair muscle injured by a growing tumor and will identify new therapeutic targets.




PETER HOUGHTON, PhD, professor of Medicine and a member of the OSUCCC – James Experimental Therapeutics Program, has received a five-year, $7.8 million grant from the NCI entitled “Studies of Childhood Sarcomas” (CA165995-01A1), which seeks to identify novel therapeutic strategies for childhood sarcoma. The Program Project Grant includes researchers at the University of Virginia, the University of Central Florida and the NCI.


THOMAS SCHMITTGEN, PhD, professor and chair of Pharmaceutics and Pharmaceutical Chemistry, and
MITCH PHELPS, PhD, assistant professor of Pharmaceutics and Pharmaceutical Chemistry, both of Ohio State’s College of Pharmacy and of the OSUCCC – James Experimental Therapeutics Program, have received a five-year, $3.2 million grant (TR000914) from the National Center for Advancing Translational Sciences. Entitled “Targeted Delivery of microRNA-Loaded Microvesicle for Cancer Therapy,” the study will develop new technology for delivering microRNA drugs to tumor cells.


MITCH PHELPS, PhD






MATTHEW RINGEL, MD, professor of Medicine and member of the OSUCCC – James Molecular Biology and Cancer Genetics (MBCG) Program, was awarded a five-year, $11.3 million Program Project Grant (CA124570) from the NCI. The grant is a continuation of a study that ran from 2008 through 2013 entitled “Genetic and Signaling Pathways in Epithelial Thyroid Cancer.” Ringel also has been awarded a five-year, $11.3 million Specialized Program of Research Excellence (SPORE) grant
(CA168505-01A1) also to support thyroid cancer research.





REBECCA JACKSON, MD, associate dean for Clinical Research in Ohio State’s College of Medicine and a member of the OSUCCC – James Cancer Control Program, has been awarded a $25.4 million grant by the National Institutes of Health to support The Ohio State University Center for Clinical and Translational Science, a collaboration between the University and Nationwide Children’s Hospital created to accelerate basic science discoveries into life-saving medical advances.Read more




AWARDS AND HONORS

MIGUEL VILLALONA-CALERO,MD, professor of Medicine and of Pharmacology and director of the Division of Medical Oncology has been elected a Fellow of the American Association for the Advancement of Science for distinguished contributions in experimental therapeutics and conducting clinical trials for translational research in cancer patients.







WOLFGANG SADÈE, PhD, professor and chair of the Department of Pharmacology at Ohio State, director of Pharmacogenomics and member of the OSUCCC – James Experimental Therapeutics Program, has been named one of six 2013 University Distinguished Scholars. The award recognizes exceptional scholarly accomplishments by senior professors.

 




FACULTY AND PROGRAMS


BHAVANA BHATNAGAR, DO, has joined the cancer program as an assistant professor in the Division of Hematology. Her clinical interests include acute myeloid leukemia and myelodysplastic syndromes. Her research interests include experimental therapeutics for myeloid malignancies. She came to Ohio State from the University of Maryland Marlene and Stewart Greenebaum Cancer Center.





DUKAGJIN M. BLAKAJ, MD, PhD, has joined the cancer program as an assistant professor in the Division of Hematology. Her clinical interests include acute myeloid leukemia and myelodysplastic syndromes. Her research interests include experimental therapeutics for myeloid malignancies. She came to Ohio State from the University of Maryland Marlene and Stewart Greenebaum Cancer Center.




JIAN CHEN, MD, PhD, has joined the cancer program as a clinical assistant professor of Pathology. His clinical interests include transfusion medicine, cellular therapy and coagulation. His research interests include stem-cell therapy, immunotherapy and hemostasis. He came to Ohio State from The Methodist Hospital at Houston, TX.





JOSHUA COLEMAN, MD, has joined the cancer program as a clinical assistant professor of Pathology. His clinical interests include molecular oncologic testing, molecular and morphologic hematopathologic testing and next-generation sequencing technologies. His research interests include myeloid and lymphoid neoplasia. He came to Ohio State from the University of Utah.




SHABANA DEWANI, MBBS, has joined the cancer program as an assistant professor in the Division of Medical Oncology. Her clinical interests include general oncology and benign and malignant hematological diseases. Her research interests include investigational therapies in gastrointestinal cancers.




AHARON FREUD, MD, PhD, has joined the cancer program as an assistant professor of Pathology. His clinical interests include the diagnosis of leukemia and lymphoma.  His research interests include innate lymphocyte biology, and EBV-associated T-cell and B-cell lymphomas. He came to Ohio State from Stanford University Medical Center.




ALEJANDRO GRU, MD has joined the cancer program as a clinical assistant professor of Pathology, after residency and fellowship training at Washington University School of Medicine in St. Louis. His clinical interests include hematopathology and dermatopathology. His main areas of research interest include cutaneous lymphoproliferative and myeloproliferative disorders.







KARL HAGLUND, MD, PhD has joined the cancer program as a clinical assistant professor of Radiation Oncology. His clinical interests include sarcomas and thoracic malignancies. His research interests include improving outcomes for patients with soft tissue sarcomas.









JESSICA HEMMINGER, MD, has joined the cancer program as a clinical assistant professor of Pathology. Her clinical and research interests are in the areas of hematopathology and renal pathology. She came to Ohio State following a fellowship at Ohio State.







MATTHEW KINZIE, MD, has joined the cancer program as a clinical assistant professor of Radiology. His clinical interests include abdominal and pelvic MRI, non-vascular interventional radiology including liver and renal tumor radiofrequency ablation. His research interests include abdominal MRI, body interventional radiology. He came to Ohio State from Wake Forest Baptist Medical Center.  



 

DAVID LIEBNER, MD, has joined the cancer program as an assistant professor in the Division of Medical Oncology. His clinical interests include sarcoma and melanoma. His research interests include genomic profiling of rare tumors, drug development and cancer systems biology. He came to Ohio State after completing a fellowship at Ohio State.



WHITNEY LUKE, MD, has joined the cancer program as a clinical assistant professor of Physical Medicine and Rehabilitation. Her clinical interests include cancer rehabilitation, electromyography and musculoskeletal disorders.





 

SAM MIKHAIL, MD, has joined the cancer program as a clinical assistant professor of Medical Oncology. His clinical interests include gastrointestinal cancers and symptom management with a special focus on esophageal and gastric cancers. His research interests include new drug development, personalized medicine and developing multidisciplinary strategies to treat esophageal and gastric cancer. He came to Ohio State from Georgetown University-Lombardi Cancer Center.




RAPHAEL POLLOCK, MD, PhD, has joined the cancer program as a professor and as director of the Division of Surgical Oncology. His clinical interests include soft-tissue sarcoma. His research interests include sarcoma molecular biology and development of novel therapies for sarcoma. He came to Ohio State from The University of Texas MD Anderson Cancer Center.  





LUCIANO PREVEDELLO, MD, has joined the cancer program as a clinical assistant professor of Radiology. His clinical interests include neuroradiology. His research interests include neuroradiology; imaging informatics. He came to Ohio State from Brigham and Women’s Hospital - Harvard Medical School.







ASHLEY ROSKO, MD, has joined the cancer program as a clinical assistant professor in the Division of Hematology. Her clinical and research interests include plasma cell dyscrasias and older adults with hematologic malignancy. She came to Ohio State from Case Medical Center in Cleveland.







BENJAMIN J. SWANSON, MD, PhD, has joined the cancer program as a clinical assistant professor of Pathology. His clinical interests include gastrointestinal and liver cancer, head and neck cancer, and bone/soft tissue cancer. His research interests include hepatocellar neoplasia, gastrointestinal neuroendocrine neoplasia, mechanisms of metastasis and head and neck pathology. He came to Ohio State from the University of Nebraska Medical Center.




GARY TOZBIKIAN, MD, has joined the cancer program as a clinical assistant professor of Pathology. His clinical interests include breast pathology. His research interests include molecular mechanisms of breast cancer development and response to treatment. He came to Ohio State from Memorial Sloan-Kettering Cancer Center.








TIMOTHY UDOJI, MD, has joined the cancer program as a clinical assistant professor in the Division of Pulmonary, Allergy, Critical Care and Sleep Medicine. He is the associate director of the Interventional Pulmonology Program at Ohio State. His clinical interests include lung cancer, lung nodules and airway diseases. His research interests include airway stents, endobronchial ultrasound and patient-related outcomes. He came to Ohio State from Emory University.





TZU-FEI WANG, MD, has joined the cancer program as a clinical assistant professor in the Division of Hematology. Her clinical focus is hemostasis and thrombosis, including venous thromboembolism, von Willebrand disease, hemophilia, other rare bleeding disorders, anemia and thrombocytopenia. Her research interests include obesity and venous thrombosis, prevention of venous thrombosis, and hemophilia. She came to Ohio State from Washington University in St. Louis.





THE OHIO STATE UNIVERSITY FOUNDATION has received a gift of $10 million from the JEGS Foundation. The gift to the new 306-bed cancer hospital, due to open in 2014, is intended to help transform cancer treatment and research at the OSUCCC – James. JEGS Foundation was started by the Coughlin family, who own JEGS Automotive Inc.



THE OHIO STATE UNIVERSITY has signed a worldwide agreement with Microlin Bio Inc. to license a large portfolio of Ohio State cancer discoveries. It includes nearly 100 issued and pending microRNA patents related to the diagnosis and treatment of prostate, ovarian, colon and lung cancers. OSUCCC – James researchers Carlo M. Croce, MD, Robert Lee, PhD, and collaborators at the National Cancer Institute and National Institutes of Health developed the technologies. Read more online

LEADERSHIP ACTIVITIES AND ACCOMPLISHMENTS


ARNAB CHAKRAVARTI, MD, professor and chair of the Department of Radiation Oncology and a member of the OSUCCC – James Experimental Therapeutics Program, will serve as scientific program chair for the 2014 American College of Radiation Oncology annual meeting.

 





RICHARD GOLDBERG, MD, physician-in-chief at the OSUCCC – James, has been appointed to the American Society of Clinical Oncology’s (ASCO) Government Relations Committee. The Committee advocates on behalf of the Society’s more than 30,000 professional oncology members and the patients they serve.







PIERLUIGI PORCU, MD, associate professor in the Division of Hematology and member of the OSUCCC – James Viral Oncology Program, has been elected to a three-year term as president of the United States Cutaneous Lymphoma Consortium, a multidisciplinary society of physicians who collaborate to improve the quality of life and prognosis of patients with cutaneous lymphoma.







LEIGHA SENTER-JAMIESON, CGC, associate professor in the Division of Human Genetics, has been elected as an at-large member of the 2014 Board of Directors for the National Society of Genetic Counselors. Two other Ohio State faculty serving on the national board are Rebecca Nagy, MS, CGC, immediate past president, and Amy Sturm, MS, CGC, director-at-large. Nagy and Sturm are also associate professors in the Division of Human Genetics.





CHARLES SHAPIRO, MD, director of Breast Medical Oncology and leader of the Breast Cancer Research Program at the OSUCCC – James, has been appointed to serve for a year as chair-elect for the Survivorship Committee of the American Society of Clinical Oncology (ASCO). After his term, Shapiro will become chair for a year and then serve as immediate past chair for another year. Read more online.



IN MEMORIAM

BERTHA A. BOURONCLE, MD, a professor emerita of Medicine at Ohio State who was the first to identify hairy cell leukemia and later helped develop an effective therapy for it, died Aug. 16. “Dr. Bouroncle was a compassionate physician, a superb researcher and a highly respected educator,” says OSUCCC Director and James CEO Michael A. Caligiuri, MD. “With her passing, we have lost a great scholar and friend.”





 

 
16-Jan-14
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