About Endometrial Cancer

The endometrium is the lining of the uterus, which is the hollow, muscular organ in a woman’s pelvis where a fetus grows. The endometrial lining is what normally sheds every month if a woman does not become pregnant. Certain changes in the cells of the endometrium may lead to cancer. 

Each year, about 53,000 women are diagnosed with endometrial cancer, making it the most frequently diagnosed gynecological cancer in the United States. The average age at diagnosis is 60, and the disease occurs most often in postmenopausal women.

There are different types of endometrial cancer. The type diagnosed most often begins in endometrium’s glandular cells and is called ndometriod adenocarcinoma.

Cancer that begins in the connective tissue or muscle wall of the uterus, called uterine sarcoma, is not as frequently diagnosed as endometriod adenocarcinoma.

Endometrial StageIA IB

There is no such thing as a routine endometrial cancer. Every patient’s disease is different, with different, individually unique genes and molecules driving that specific disease.

At the OSUCCC – James, our gynecologic cancer sub-specialists are world-renowned cancer experts who focus solely on these tumors and who reach across medical disciplines (medical oncologists, surgical oncologists, radiation oncologists, pharmacists, nurse sub-specialists and more) to design the very best treatment plan and therapies to target each patient’s specific cancer.

In fact, our unique Multidisciplinary Endometrial Cancer Clinic offers all newly diagnosed patients an on-site, thorough evaluation and treatment-options review with experts from medical oncology, surgical oncology, radiation oncology, and more – all on the same day – so that together, the patient and the experts can decide on the best personalized treatment options.

Additionally, patients have access to advanced treatment procedures performed only at the OSUCCC – James by internationally recognized experts in endometrial cancer.

And by offering access to the country’s most advancedclinical trials right here at the OSUCCC – James, patients know that additional options, when needed, are often available for their treatment and care.

Endometrial Cancer Symptoms

Endometrial cancer that has just formed, or that is early in its progress, may not cause any symptoms. When symptoms do occur, they may include:

  • Vaginal bleeding or discharge not related to menstruation (periods)
  • Difficult or painful urination
  • Pain during sexual intercourse
  • Pain in the pelvic area

(Source: National Cancer Institute)

Having these symptoms does not necessarily mean you have endometrial cancer. But if you have symptoms, you should tell your doctor, especially if symptoms have continued for longer than a few weeks.

If you’ve been diagnosed with endometrial cancer, would like a second opinion or would like to speak with an endometrial cancer specialist, please call The James Line at 800-293-5066 or 614-293-5066 to make an appointment.

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The James Cancer Hospital and Solove Research Institute

460 W. 10th Ave.

Columbus, Ohio 43210


Patient Story

Patient Stories Amy Ervin

Amy Ervin

After finding out she had endometrial cancer, Amy began a quest to find the top experts and hospital. Multiple sources and recommendations pointed her to Dr. Fowler at the OSUCCC ­– James.

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