Gastrointestinal Cancers

The world-renowned experts at the OSUCCC – James are transforming the way gastrointestinal cancers are prevented, detected, treated and cured.

Today, cancer is no longer solely defined by location or even by stage. We know there is no routine cancer, and there are no routine gastrointestinal cancers.

Gastrointestinal cancers are complex diseases. Each patient’s cancer is different, behaving differently in the bodies they’re in and calling for a tailored, individualized treatment plan for each patient.

To deliver the most effective gastrointestinal cancer detection and treatment, our nationally renowned experts identify and understand cancer at the biologic and genetic levels, unlocking the molecular code of a patient’s disease and pinpointing what makes each cancer grow — then discovering what stops it.

Our team of gastrointestinal cancer subspecialists spans a broad range of disciplines: from medical, surgical and radiation oncologists to molecular and biological pathologists, genetic scientists and more — all specializing in a particular type  of gastrointestinal cancer (and only that gastrointestinal cancer) research, prevention, detection, treatment and cure.  

It’s that subspecialization and singular focus that enable us to discover, develop and deliver the most targeted therapies for each individual gastrointestinal cancer patient.  

And that means our collective expertise leads to improved outcomes, faster responses, fewer side effects and more hope for cancer patients everywhere.

Anal Cancer

Anal cancer is rare, rarer than colon cancer or rectal cancer. Treatment can be successful if caught early. The primary form of anal cancer in the United States is squamous cell carcinoma, caused primarily by human papilloma virus (HPV) infection. We have one of the most advanced cancer programs in the nation, and our pathologists are highly experienced in diagnosing anal cancer.

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Colon Cancer

Colon cancer is a type of cancer that begins in the colon, an organ that is part of the large intestine and the body’s digestive system. Identifying the type of drivers of your colon cancer and delivering drugs that target those drivers are powerful weapons against this disease, and weapons we specialize in.

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Esophageal Cancer

Esophageal cancer most often starts in the lining, or outer layer, and moves out into the other layers as it grows. The cancer is fairly rare — only 18,000 Americans are diagnosed with esophageal cancer every year. At OSUCCC – James, we’re transforming the way esophageal cancer is prevented, detected, treated and cured.

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Gallbladder Cancer

Gallbladder cancer is a rare cancer of the organ in the abdomen that stores bile. Cancer can develop in the gallbladder or bile ducts, which are thin tubes that carry bile from the liver. More than 10,000 new cases of gallbladder and bile duct cancers are diagnosed each year in the U.S. At OSUCCC – James, we understand gallbladder cancer at the molecular and genetic level to deliver the most effective treatments.

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Liver Cancer

The liver performs many vital functions such as storing nutrients and filtering and breaking down toxins in the blood. The vast majority of liver cancer occurs in people older than 45. Worldwide, this disease is one of the leading causes of cancer deaths. However, survival rates for people with liver cancer are beginning to improve as a result of new, targeted therapies like those pioneered at OSUCCC – James.

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Pancreatic Cancer

Pancreatic cancer is a disease in which cancer cells form in the pancreas, a narrow gland that lies between the stomach and spine. We understand that there is no routine Hodgkin’s lymphoma. We work at the leading edge of cancer medicine to target and stop cancer at its genetic and molecular roots, which allows us to pinpoint what makes each cancer grow and discover what stops it.

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Rectal Cancer

Rectal cancer begins in the rectum. It’s also called colorectal cancer because it can occur above the rectum, in the colon or in the rectum. Some people are at higher risk because of a family history of certain genetic disorders such as Lynch syndrome. Our rectal cancer specialists dedicate their lives to supporting and caring for patients and their families.

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Small Intestine Cancer

Small intestine cancer, also known as small bowel cancer, begins in cells of the small intestine, the part of the digestive system located between the stomach and large intestine. It’s rare, affecting about 9,000 people a year in the United States. At OSUCCC – James, we have world-renowned medical, surgical and radiation oncology experts who focus on only small intestine cancer.

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Stomach (Gastric) Cancer

Nearly all stomach cancers start in the inner lining of the stomach. More than 22,000 cases of stomach cancer are diagnosed in the United States each year. Most are diagnosed in people who are 65 or older. We have one of the nation’s largest and most extensive genomics and tumor-sequencing programs, enabling our experts to target the specific cells driving your stomach cancer.

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The James Cancer Hospital and Solove Research Institute

460 W. 10th Ave.

Columbus, Ohio 43210


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