Gastrointestinal Cancers

The world-renowned experts at the OSUCCC – James are transforming the way gastrointestinal cancers are prevented, detected, treated and cured.

Today, cancer is no longer solely defined by location or even by stage. We know there is no routine cancer, and there are no routine gastrointestinal cancers.

Gastrointestinal cancers are complex diseases. Each patient’s cancer is different, behaving differently in the bodies they’re in and calling for a tailored, individualized treatment plan for each patient.

To deliver the most effective gastrointestinal cancer detection and treatment, our nationally renowned experts identify and understand cancer at the biologic and genetic levels, unlocking the molecular code of a patient’s disease and pinpointing what makes each cancer grow — then discovering what stops it.

Our team of gastrointestinal cancer subspecialists spans a broad range of disciplines: from medical, surgical and radiation oncologists to molecular and biological pathologists, genetic scientists and more — all specializing in a particular type  of gastrointestinal cancer (and only that gastrointestinal cancer) research, prevention, detection, treatment and cure.  

It’s that subspecialization and singular focus that enable us to discover, develop and deliver the most targeted therapies for each individual gastrointestinal cancer patient.  

And that means our collective expertise leads to improved outcomes, faster responses, fewer side effects and more hope for cancer patients everywhere.

Anal Cancer

Anal cancer is rare. Only about 7,200 new cases are diagnosed each year, with the majority of cases occurring in adults with an average age of 60. The OSUCCC – James gastrointestinal team includes preeminent experts in the study, diagnosis and treatment of anal cancer. This mutlidisciplinary team of subspecialists determines the best treatment for each patient based on his or her specific, individual anal cancer.

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Colon Cancer

Colon cancer begins in the colon, which is part of the body’s digestive system. About 145,000 colon cancer cases are diagnosed in the United States each year. There is no routine colon cancer, nor is there ever a routine way to treat it and so the OSUCCC – James team of subspecialists determine the best treatment for each patient based on his or her specific, individual colon cancer.

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Esophageal Cancer

The esophagus is a hollow, muscular tube that moves food and liquid from the throat to the stomach. Esophageal cancer most often starts in the lining, or outer layer, and moves out into the other layers as it grows. At the OSUCCC – James, our esophageal cancer specialists are world-renowned cancer experts who focus solely on esophageal cancer and who reach across medical disciplines to design the very best treatment plan and therapies to target each patient’s specific cancer.

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Gallbladder Cancer

Gallbladder cancer is a rare cancer of the organ in the abdomen that stores bile, a fluid made by the liver. Cancer can develop in the gallbladder or in the bile ducts, which are thin tubes that carry bile from the liver. At the OSUCCC – James, gallbladder cancer patients have a team of experts that includes medical oncologists, surgical oncologists, radiation oncologists, geneticists, gastroenterologists, hepatologists, nutritionists and more.

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Liver Cancer

The liver is the largest internal organ in the body. It performs many vital functions such as storing nutrients, filtering and breaking down toxins in the blood. More than 33,000 cases of liver cancer are diagnosed in the United States each year. It affects more men than women. Not only are expert cancer researchers at the OSUCCC – James continually working to detect and diagnose liver cancer early, but they are also developing additional tests to detect and diagnose cancer even earlier, leading to improved outcomes, faster responses and fewer side effects.

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Pancreatic Cancer

Pancreatic cancer is the second most prevalent cancer of the gastrointestinal area, and about 46,000 cases are diagnosed each year in the United States. About 90 percent of pancreatic cancers develop in duct cells. Because pancreatic cancer is one of the top ten cancers diagnosed in the country, the OSUCCC – James is consistently paving the way in learning more about what causes pancreatic cancer — leading to even more highly targeted prevention, care and treatment.

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Rectal Cancer

Rectal cancer begins in the rectum. It’s also called colorectal cancer because it can occur above the rectum, in the colon or in the rectum. OSUCCC – James rectal cancer researchers sequence tumors to identify key molecules that fuel each patient’s rectal cancer and then develop drugs that target only those particular molecules.

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Small Intestine Cancer

Small intestine cancer begins in cells of the small intestine, the part of the digestive system located between the stomach and large intestine. It’s rare, affecting about 9,000 people a year in the U.S. Every patient’s small intestine cancer is different and OSUCCC – James experts target the individually unique genes and molecules driving each person’s small intestine cancer.

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Stomach (Gastric) Cancer

Nearly all stomach cancers start in the inner lining of the stomach. More than 22,000 cases of stomach cancer are diagnosed in the United States each year. At the OSUCCC – James, cancer research experts focus on studying stomach cancer prevention, diagnosis, treatment and cure.

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The James Cancer Hospital and Solove Research Institute

460 W. 10th Ave.

Columbus, Ohio 43210


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