There is no such thing as routine soft tissue sarcoma. Every patient’s soft tissue sarcoma is different, with different, individually unique genes and molecules driving each person’s specific cancer.

At the OSUCCC – James, our soft tissue sarcoma specialists are world-renowned cancer experts who focus solely on soft tissue sarcoma and who reach across medical disciplines (oncologists, surgeons, radiologists, pharmacists and more) to design the very best treatment plan and therapies to target each patient’s specific cancer.

And by offering access to the country’s most advanced clinical trials right here at the OSUCCC – James, patients know that additional options, when needed, are often available for their treatment and care.

Facts About Soft Tissue Sarcoma

Soft tissue sarcoma can form in any of the body’s tissues, including the lymph vessels, the thin tubes that connect lymph nodes. In adults, most soft tissue sarcomas form in the arms, legs, head, neck, trunk, abdomen and retroperitoneum (pelvis).

More than 12,000 new cases of soft tissue sarcoma are diagnosed in the United States each year.

Types of Soft Tissue Sarcoma

Soft tissue sarcomas are classified according to the types of cells in which they begin. They include:

  • Adipocytic tumors
  • Fibroblastic/myofibroblastic tumors
  • So-called fibrohistiocytic tumors
  • Smooth muscle tumors
  • Skeletal muscle tumors
  • Vascular tumors
  • Tumors of peripheral nerves
  • Chondro-osseous tumors
  • Tumors of uncertain differentiation

Each of these types has at least one subtype that further clarifies the cells involved in the sarcoma.

(Source: National Cancer Institute)

Soft Tissue Sarcoma Symptoms

A sarcoma may appear as a painless lump under the skin, often on an arm or a leg. Sarcomas that begin in the abdomen may not cause signs or symptoms until they grow to a noticeable size. As the sarcoma grows and presses on nearby organs, nerves, muscles or blood vessels, signs and symptoms may include:

  • Pain
  • Difficulty breathing

(Source: National Cancer Institute)

Having these symptoms does not necessarily mean you have soft tissue sarcoma. But if you have symptoms, you should tell your doctor, especially if symptoms have continued for longer than a few weeks.


If you have received a soft tissue sarcoma diagnosis, or if you want a second opinion or just want to speak to a soft tissue sarcoma specialist, we are here to help you. Call 800-293-5066 or 614-293-5066 to make an appointment.

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The James Cancer Hospital and Solove Research Institute

460 W. 10th Ave.

Columbus, Ohio 43210


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