Rachel Layman, MD

The James Cancer Center
Rachel Layman

Clinical Expertise

  • Medical Oncology
  • Breast Cancer
  • Drug Discovery
  • Carcinoma, Ductal, Breast
  • Carcinoma, Ductal
  • Hereditary Breast and Ovarian Cancer Syndrome
  • Male Breast Cancer
  • Inflammatory Breast Cancers
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I am a medical oncologist who specializes in managing the treatment of patients with breast cancer. Together with a multidisciplinary breast cancer treatment team, I specialize in the diagnosis, assessment and management of treatment plans for patients.

I manage the care for female and male patients with breast cancers, including inflammatory breast cancers. My clinical expertise extends to treating women who are at high risk of developing breast and ovarian cancers, otherwise called hereditary breast and ovarian cancer syndrome. In my work with the high-risk breast cancer program, I test high-risk patients for genes associated with breast and ovarian cancers. Identifying inheritable genes will help us not only determine the level of risk for developing breast and ovarian cancers, but also identifying cancer early, when the prognosis is generally more favorable. I also treat patients with hereditary breast and ovarian syndrome who develop breast cancer.

My research primarily focuses on assessing the efficacy and safety of existing drugs used in treating patients with breast cancer. I have published extensively in this area of research and have contributed to numerous other studies on the effectiveness and safety of drugs used in combination with chemotherapy treatments.

I am a member of the National Comprehensive Cancer Network Breast Cancer Risk Reduction Panel, and I have authored articles that appeared in Journal of Clinical Oncology, Breast Cancer Research, and Clinical Cancer Research.

Education and Background


  • Case Western Reserve University School of Medicine

    Cleveland, OH


  • University Hospitals of Cleveland

    Cleveland, OH


  • Hematology/Oncology

    University of Michigan Medical Center

Board Certifications

  • American Board of Internal Medicine
  • American Board of Internal Medicine (Subspecialty: Medicine Oncology)

Academic Department


Clinical Trials | Lead

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