Dr. Clinton to Discuss Prostate Cancer During 'Fireside Chat
COLUMBUS, Ohio – Community members are invited to attend a “fireside chat” about prostate cancer with Dr. Steven Clinton, program leader of molecular carcinogenesis and chemoprevention at The Ohio St
Combination Peptide Therapies Might Offer More Effective, Less Toxic Cancer Treatment
Tiny fragments of proteins called peptides potentially offer an effective, safer, way to prevent or treat cancer.
These two studies examine a peptide vaccine and a peptide therapeutic together and wi
The James Cancer Hospital Expands Gastrointestinal Oncology Program
COLUMBUS, Ohio – The section of gastrointestinal oncology at The Ohio State University Comprehensive Cancer Center – James Cancer Hospital and Solove Research Institute (OSUCCC-James) continues to ex
Electric Helmet Treats Brain Tumors
COLUMBUS, Ohio – Brain cancer patients at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC–James) are among the
People With Allergies May Have Lower Risk of Brain Tumors
COLUMBUS, Ohio - New research adds to the growing body of evidence suggesting that there’s a link between allergies and reduced risk of a serious type of cancer that starts in the brain. This study su
Liver Cancer Cells Stop Making Glucose As They Become Cancerous
Liver cells normally produce glucose to help maintain healthy blood-sugar levels, but they lose that ability when they become cancerous, this study shows.
This change might benefit tumor cells by hel
Loss Of A Tiny Liver Molecule Might Lead To Liver Cancer
Liver cancer is the third leading cancer killer worldwide and new treatments are urgently needed.
This study shows that loss of a regulatory molecule called microRNA-122 leads to liver cancer.
Study Reveals New Mechanism That Might Promote Cancer’s Growth And Spread In The Body
Researchers have discovered a previously unknown mechanism that promotes the growth and spread of cancer.
The mechanism involves a new role for small regulatory molecules called microRNA.
Ohio State Cancer Researcher Receives Carcinogenesis Award
COLUMBUS, Ohio – Dr. Carlo Croce, chair of the department of molecular virology, immunology, and medical genetics; and director of Human Cancer Genetics at The Ohio State University Comprehensive Canc
miR Loss May Power Malignant Transformation In Chronic Leukemia
These findings show that the loss of a particular RNA molecule enables leukemia cells to generate energy in a way that allows them to rapidly produce materials they need to proliferate faster.
Goldberg Gives Moertel Lecture At Alliance Meeting
COLUMBUS, Ohio – Dr. Richard Goldberg, (43235) an internationally renowned gastrointestinal oncologist at The Ohio State University Comprehensive Cancer Center – James Cancer Hospital and Solove Resea
Paskett Presents Jimmie Holland Lecture at National Alliance Meeting
COLUMBUS, Ohio – Ohio State University cancer researcher Electra Paskett (43017) presented the 12th annual Jimmie Holland lecture during the recent Alliance for Clinical Trials in Oncology meeting in
Ohio State Leukemia Researcher Receives National Schilsky Award
COLUMBUS, OHIO – Dr. Clara Bloomfield (43015), an international authority on leukemia and lymphoma at The Ohio State University Comprehensive Cancer Center – James Cancer Hospital and Solove Research
International Expert In Breast Radiation Oncology Joins The James
COLUMBUS, Ohio – Internationally renowned cancer expert Dr. Julia White is the new director of breast radiation oncology at The Ohio State University Comprehensive Cancer Center – Arthur G. James Can
Inhibitors Of Shuttle Molecule Show Promise In Acute Leukemia
An estimated 10,200 Americans will die of acute myeloid leukemia (AML) in 2012, so new ways of treating the disease are needed.
This study uses a novel class of experimental drugs to halt a process
Scientists Sequence Genome Of Human Relative That Prefers Love Over War
Researchers have sequenced the bonobo genome and compared it to the genomes of chimpanzees and humans.
The findings should help scientists better understand the evolutionary relationships between
Marker Distinguishes More-Aggressive From Less-Aggressive Forms Of Chronic Leukemia
People newly diagnosed with chronic leukemia must often wait to learn if they have a faster- or slower-progressing form of the disease.
This study identified a molecular marker that quickly helps to
Researchers Identify a “Life-And-Death” Molecule on Chronic Leukemia Cells
SMIP-016 is a promising experimental drug that kills chronic leukemia cells.
The drug targets a protein called CD37, but it wasn’t known how this kills leukemia cells.
This study showed unexpected
Revised Glioblastoma Classification Should Improve Patient Care
Classification Should Improve Patient Care
The system doctors use to classify patients’ malignant brain
tumors is outdated.
Researchers have revised the
Inherited DNA Change Explains Overactive Leukemia Gene
An overactive BAALC gene in acute leukemia cells identifies patients whose disease is likely to respond poorly to standard therapy.
This study discovered why the gene is often overactive.
Experimental Agent May Help Older People With Chronic Leukemia
· Standard treatment for chronic leukemia is too harsh for many older patients.
· Early clinical trials testing indicates that these patients respond well to the experimental drug
Public To Sign Beam At Statehouse For New James Cancer Hospital, Critical Care Center
COLUMBUS, Ohio – The final steel beams of the new James Cancer Hospital and Solove Research Institute and Critical Care Center will be raised on May 21 – an important milestone in building the future
A microRNA Prognostic Marker Identified In Acute Leukemia
Molecular markers are needed to guide the treatment of people with acute leukemia with normal-looking chromosomes.
This study found that overexpression of a particular microRNA indicates a poor progn
James Nurses Receive Multiple Awards From Oncology Nursing Society
COLUMBUS, Ohio – Two nursing professionals at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute will receive awards
29th Block Golf Tournament to Help Fund New James Cancer Hospital
COLUMBUS, Ohio – The 29th Herbert J. Block Memorial Tournament will be held June 25 at the Muirfield Village Golf Club in Dublin, Ohio. Proceeds from the event will benefit the expansion of
11th Annual 'Celebration for Life' to Benefit The James
COLUMBUS, Ohio – The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute will host the 11th annual “Celebration for Life” fundr
Beam Signings for New James Cancer Hospital, Critical Care Center
COLUMBUS, Ohio – The final steel beams of the new James Cancer Hospital and
Solove Research Institute and Critical Care Center will be raised on May 21 – an important milestone in building t
Two Repressor Genes Identified As Essential For Placental Development
The E2F family of genes is thought to play a crucial role in regulating cell proliferation.
It is unclear how these genes carry out their function and interact with one another in intact animals.
James Cancer Hospital to Offer Free Skin Cancer Screenings
COLUMBUS, Ohio – The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC–James) is offering free screenings for skin ca
Study Suggests Current Definition of Circulating Tumor Cells Too Narrow; Finds New Characteristics of Double Positive Cells
COLUMBUS, Ohio – New research from The Ohio State University utilizes two different methods to visualize circulating tumor cells (CTCs) as well as other unusual circulating cells with both epithelia
Spielman Funds at James Cancer Hospital Top $10 Million
COLUMBUS, Ohio – What started as a quest by Chris and Stefanie Spielman to raise $250,000 for breast cancer research has been embraced by the central Ohio community – so much so – that mor
Dr. Mayr Inducted as Fellow of American Society for Radiation Oncology
COLUMBUS, Ohio – Dr. Nina A. Mayr, professor of radiation oncology at the Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research
Oncology Nursing Society Publication Edited By Ohio State Nurse Receives Award
COLUMBUS, Ohio – Research scientist Joanne Lester, who holds a doctorate of philosophy in nursing at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Ri
Playing Football Was My Passion, But Fighting Cancer is My Purpose
Chris Spielman was a four-time Pro Bowl linebacker, Ohio State football legend, and perhaps the only high school student to appear on a Wheaties box. But he didn't tackle his toughest opponent until h
Cancer Cells Send Out The Alarm On Tumor-Killing Virus
Cancer-killing, or oncolytic, viruses show promise as therapy for brain tumors.
Clinical trials indicate that oncolytic virus therapy is safe but not as effective as expected in humans.
This study d
Blochs Commit $5 Million To Construction Of New James Cancer Hospital
COLUMBUS, Ohio – Janis and Michael Bloch of Bexley, Ohio, recently committed $5 million to the construction of the new Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, part of
Stefanie's Champions Luncheon Honors Cancer Caregivers
COLUMBUS, Ohio – The 13th annual Stefanie’s Champions Awards luncheon will honor five extraordinary heroes in the lives of cancer patients in the Archie M. Griffin Grand Ballroom at The Ohio Stat
Mini-Molecule Governs Severity Of Acute Graft-Vs-Host Disease, Study Finds
Graft-versus-host disease is a life-threatening problem for many bone-marrow transplant recipients.
New therapies are urgently needed to control the condition.
This study identifies a molecule that
Ohio State Surgeons Pioneer Removal Of Skull-Based Tumors Through the Nose and Mouth
COLUMBUS, Ohio – Surgeons at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC– James) Cranial Base Center have d
Tonsils Make T-Cells, Too, Ohio State Study Shows
T lymphocytes, or T cells, are essential for effective immune responses.
T cells were thought to be produced only in the thymus gland.
This study shows that T cells are also produced in the tonsils,
Dr. Chakravarti Inducted as Fellow of American College of Radiation Oncologists
COLUMBUS, Ohio – Dr. Arnab Chakravarti, chair and professor of Radiation Oncology, Max Morehouse Chair of Cancer Research, and co-director of the brain tumor program at the Ohio State University
James Cancer Experts to Compete in 'Top Doc' Cooking Challenge
COLUMBUS, Ohio – The first-ever “Top Doc” Cooking Challenge – an informational and entertaining food event similar to the popular TV shows “Top Chef” and “Chopped” – will feature four Ohio State
Mobile DNA Elements Can Disrupt Gene Expression And Cause Biological Variation, Study Shows
Numerous mouse strains show great biological variation in features such as behavior, coat color and susceptibility to cancer and other diseases.
This study examines one possible genetic cause fo
Oncolytic Virus Extends Survival In Medulloblastoma Model
Medulloblastoma is the most common malignant brain tumor in children.
Disseminated medulloblastoma is particularly lethal and requires extensive radiation therapy to the brain, which can cause bra
Understanding How Early Breast Tumors Become Deadly: A Small Group Of Molecules Might Hold The Answer
Some early-stage breast cancers are potentially harmless, but others invade surrounding healthy tissue and become deadly.
This study has identified a small pattern of molecules that highlights impo
Leaders From South Korea’s Cancer Center Travel To Ohio State To Learn Best Practices In Cancer Research And Care
COLUMBUS, Ohio – Leaders from Samsung Cancer Center, located in Seoul, South Korea, traveled 7,000 miles, flying for more than a day and crossing 14 hours in time zones, just to have the opportunity t
Oral HPV Infection is Three Times More Common in Men than Women, Study Shows
First author and study leader Dr. Maura Gillison, medical oncologist and head and neck cancer specialist at the OSUCCC – James, describes the findings of her paper, “Prevalence of Oral HPV Infect
Study Reveals Mechanism Of Lung-Cancer Drug Resistance
The most common form of lung cancer inevitably develops resistance to the targeted drug gefitinib.
This study shows how this resistance develops.
The findings suggest a new strategy for treating non
Dr. Caligiuri to Host 'Fireside Chat' About the Future of Cancer Research
COLUMBUS, Ohio – Michael A. Caligiuri, MD, director of The Ohio State University Comprehensive Cancer Center and CEO of the James Cancer Hospital and Solove Research Institute, will discuss the future
Anti-Sense Might Make Sense For Treating Liver Cancer
COLUMBUS, Ohio – A new study shows that it is possible to selectively target and block a particular microRNA that is important in liver cancer. The finding might offer a new therapy for this malignanc