Marker Distinguishes More-Aggressive From Less-Aggressive Forms Of Chronic Leukemia
People newly diagnosed with chronic leukemia must often wait to learn if they have a faster- or slower-progressing form of the disease.
This study identified a molecular marker that quickly helps to
Researchers Identify a “Life-And-Death” Molecule on Chronic Leukemia Cells
SMIP-016 is a promising experimental drug that kills chronic leukemia cells.
The drug targets a protein called CD37, but it wasn’t known how this kills leukemia cells.
This study showed unexpected
Inherited DNA Change Explains Overactive Leukemia Gene
An overactive BAALC gene in acute leukemia cells identifies patients whose disease is likely to respond poorly to standard therapy.
This study discovered why the gene is often overactive.
Revised Glioblastoma Classification Should Improve Patient Care
Classification Should Improve Patient Care
The system doctors use to classify patients’ malignant brain
tumors is outdated.
Researchers have revised the
Experimental Agent May Help Older People With Chronic Leukemia
· Standard treatment for chronic leukemia is too harsh for many older patients.
· Early clinical trials testing indicates that these patients respond well to the experimental drug
Public To Sign Beam At Statehouse For New James Cancer Hospital, Critical Care Center
COLUMBUS, Ohio – The final steel beams of the new James Cancer Hospital and Solove Research Institute and Critical Care Center will be raised on May 21 – an important milestone in building the future
A microRNA Prognostic Marker Identified In Acute Leukemia
Molecular markers are needed to guide the treatment of people with acute leukemia with normal-looking chromosomes.
This study found that overexpression of a particular microRNA indicates a poor progn
James Nurses Receive Multiple Awards From Oncology Nursing Society
COLUMBUS, Ohio – Two nursing professionals at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute will receive awards
29th Block Golf Tournament to Help Fund New James Cancer Hospital
COLUMBUS, Ohio – The 29th Herbert J. Block Memorial Tournament will be held June 25 at the Muirfield Village Golf Club in Dublin, Ohio. Proceeds from the event will benefit the expansion of
11th Annual 'Celebration for Life' to Benefit The James
COLUMBUS, Ohio – The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute will host the 11th annual “Celebration for Life” fundr
Beam Signings for New James Cancer Hospital, Critical Care Center
COLUMBUS, Ohio – The final steel beams of the new James Cancer Hospital and
Solove Research Institute and Critical Care Center will be raised on May 21 – an important milestone in building t
Two Repressor Genes Identified As Essential For Placental Development
The E2F family of genes is thought to play a crucial role in regulating cell proliferation.
It is unclear how these genes carry out their function and interact with one another in intact animals.
James Cancer Hospital to Offer Free Skin Cancer Screenings
COLUMBUS, Ohio – The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC–James) is offering free screenings for skin ca
Spielman Funds at James Cancer Hospital Top $10 Million
COLUMBUS, Ohio – What started as a quest by Chris and Stefanie Spielman to raise $250,000 for breast cancer research has been embraced by the central Ohio community – so much so – that mor
Study Suggests Current Definition of Circulating Tumor Cells Too Narrow; Finds New Characteristics of Double Positive Cells
COLUMBUS, Ohio – New research from The Ohio State University utilizes two different methods to visualize circulating tumor cells (CTCs) as well as other unusual circulating cells with both epithelia
Oncology Nursing Society Publication Edited By Ohio State Nurse Receives Award
COLUMBUS, Ohio – Research scientist Joanne Lester, who holds a doctorate of philosophy in nursing at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Ri
Dr. Mayr Inducted as Fellow of American Society for Radiation Oncology
COLUMBUS, Ohio – Dr. Nina A. Mayr, professor of radiation oncology at the Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research
Playing Football Was My Passion, But Fighting Cancer is My Purpose
Chris Spielman was a four-time Pro Bowl linebacker, Ohio State football legend, and perhaps the only high school student to appear on a Wheaties box. But he didn't tackle his toughest opponent until h
Cancer Cells Send Out The Alarm On Tumor-Killing Virus
Cancer-killing, or oncolytic, viruses show promise as therapy for brain tumors.
Clinical trials indicate that oncolytic virus therapy is safe but not as effective as expected in humans.
This study d
Blochs Commit $5 Million To Construction Of New James Cancer Hospital
COLUMBUS, Ohio – Janis and Michael Bloch of Bexley, Ohio, recently committed $5 million to the construction of the new Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, part of
Stefanie's Champions Luncheon Honors Cancer Caregivers
COLUMBUS, Ohio – The 13th annual Stefanie’s Champions Awards luncheon will honor five extraordinary heroes in the lives of cancer patients in the Archie M. Griffin Grand Ballroom at The Ohio Stat
Mini-Molecule Governs Severity Of Acute Graft-Vs-Host Disease, Study Finds
Graft-versus-host disease is a life-threatening problem for many bone-marrow transplant recipients.
New therapies are urgently needed to control the condition.
This study identifies a molecule that
Ohio State Surgeons Pioneer Removal Of Skull-Based Tumors Through the Nose and Mouth
COLUMBUS, Ohio – Surgeons at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC– James) Cranial Base Center have d
Tonsils Make T-Cells, Too, Ohio State Study Shows
T lymphocytes, or T cells, are essential for effective immune responses.
T cells were thought to be produced only in the thymus gland.
This study shows that T cells are also produced in the tonsils,
Dr. Chakravarti Inducted as Fellow of American College of Radiation Oncologists
COLUMBUS, Ohio – Dr. Arnab Chakravarti, chair and professor of Radiation Oncology, Max Morehouse Chair of Cancer Research, and co-director of the brain tumor program at the Ohio State University
James Cancer Experts to Compete in 'Top Doc' Cooking Challenge
COLUMBUS, Ohio – The first-ever “Top Doc” Cooking Challenge – an informational and entertaining food event similar to the popular TV shows “Top Chef” and “Chopped” – will feature four Ohio State
Mobile DNA Elements Can Disrupt Gene Expression And Cause Biological Variation, Study Shows
Numerous mouse strains show great biological variation in features such as behavior, coat color and susceptibility to cancer and other diseases.
This study examines one possible genetic cause fo
Oncolytic Virus Extends Survival In Medulloblastoma Model
Medulloblastoma is the most common malignant brain tumor in children.
Disseminated medulloblastoma is particularly lethal and requires extensive radiation therapy to the brain, which can cause bra
Understanding How Early Breast Tumors Become Deadly: A Small Group Of Molecules Might Hold The Answer
Some early-stage breast cancers are potentially harmless, but others invade surrounding healthy tissue and become deadly.
This study has identified a small pattern of molecules that highlights impo
Leaders From South Korea’s Cancer Center Travel To Ohio State To Learn Best Practices In Cancer Research And Care
COLUMBUS, Ohio – Leaders from Samsung Cancer Center, located in Seoul, South Korea, traveled 7,000 miles, flying for more than a day and crossing 14 hours in time zones, just to have the opportunity t
Oral HPV Infection is Three Times More Common in Men than Women, Study Shows
First author and study leader Dr. Maura Gillison, medical oncologist and head and neck cancer specialist at the OSUCCC – James, describes the findings of her paper, “Prevalence of Oral HPV Infect
Study Reveals Mechanism Of Lung-Cancer Drug Resistance
The most common form of lung cancer inevitably develops resistance to the targeted drug gefitinib.
This study shows how this resistance develops.
The findings suggest a new strategy for treating non
Dr. Caligiuri to Host 'Fireside Chat' About the Future of Cancer Research
COLUMBUS, Ohio – Michael A. Caligiuri, MD, director of The Ohio State University Comprehensive Cancer Center and CEO of the James Cancer Hospital and Solove Research Institute, will discuss the future
Anti-Sense Might Make Sense For Treating Liver Cancer
COLUMBUS, Ohio – A new study shows that it is possible to selectively target and block a particular microRNA that is important in liver cancer. The finding might offer a new therapy for this malignanc
Pelotonia To Fund 5 Postdoctoral Fellows At Ohio State
COLUMBUS, Ohio – The Pelotonia Fellowship Program, which is funded by the annual Pelotonia cycling event, will award grants to five postdoctoral students to conduct innovative cancer research at The
Ohio State Scientist Receives AMP Award For Excellence
COLUMBUS, Ohio – Dr. Carlo M. Croce, chair of the department of molecular virology, immunology, and medical genetics; and director of Human Cancer Genetics at Ohio State, received the Association for
Pelotonia To Fund Additional Cancer Research At Ohio State
COLUMBUS, Ohio – Six teams of scientists at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) are each
Hope Supports The New James Cancer Hospital And Solove Research Institute
COLUMBUS, Ohio – A 31-foot steel beam carrying messages of hope for a cancer-free world from nearly 1,000 James cancer survivors will be installed at 10:30 a.m. Thursday (12/22) at the new Arthur G
Study Reveals How Normal Cells Fuel Tumor Growth
· The study shows how normal cells in tumors can enhance the growth of the tumor’s cancer cells after losing an important tumor suppressor gene called Pten.
Scientists Discover Second-Oldest Gene Mutation
COLUMBUS, Ohio – A new study has identified a gene mutation that researchers estimate dates back to 11,600 B.C., making it the second oldest human disease mutation yet discovered.
Novel Export-Inhibitor Shows Promise For Treating CLL
COLUMBUS, Ohio – An experimental drug that works by blocking the export of key control molecules from the nucleus of cancer cells shows promise as a treatment for chronic lymphocytic leukemia (CLL)
Gene Mutation Signals A High Risk Of Recurrence In Some Older Acute-Leukemia Patients
COLUMBUS, Ohio – Older people with acute myeloid leukemia and normal looking chromosomes in their cancer cells have a higher risk of recurrence if they have mutations in a gene called ASXL1, accordi
Interim Study Shows Novel Experimental Agent is Highly Active in CLL Patients
COLUMBUS, Ohio – An interim analysis of a phase Ib/II clinical trial indicates that a novel experimental agent for chronic lymphocytic leukemia (CLL) is highly active and well tolerated in patients w
Ohio State Researchers Discover Hereditary Predisposition to Melanoma of the Eye
Ohio – Ohio State University researchers have discovered a hereditary cancer syndrome
that predisposes certain people to a melanoma of the eye, along with lung
cancer, brain cancer and po
Third Time In Three Years, The James Earns Top Hospital Status
COLUMBUS, Ohio – For the third consecutive year and fourth time in five years, the Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research I
Ohio State Studying How Chemotherapy Affects Breast Cancer Patients’ Hearts
COLUMBUS, Ohio – Ohio State University cancer and heart researchers are teaming up to find a better way to assess early cardiac injury from a class of chemotherapy drugs commonly used to treat breas
A New Study Suggests That A Neurotransmitter Might Improve The Treatment Of Cancer
COLUMBUS, Ohio – Doses of a neurotransmitter might offer a way to boost the effectiveness of anticancer drugs and radiation therapy, according to a new study led by researchers at the Ohio State Univ
Lower Antioxidant Level Might Explain Higher Skin-Cancer Rate In Males
COLUMBUS, Ohio – Men are three times more likely than women to develop a common form of skin cancer but medical science doesn’t know why. A new study may provide part of the answer.
Shapiro to Lead Breast Cancer Research Program at Ohio State
COLUMBUS, Ohio – Dr. Charles Shapiro has been named to lead the breast cancer research program at the
Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer
Hospital and Richard
NCI Funds Ohio State Breast Cancer Intervention Training
COLUMBUS, Ohio – Barbara Andersen, a professor of psychology and researcher at the Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research I