A Gene Within a Gene Contributes to the Aggressiveness of Acute Myeloid Leukemia
High expression of a gene called BAALC is known to be associated with poor survival of acute myeloid leukemia (AML) patients.
BAALC has a second smaller gene embedded within it that is also active in
Study Identifies a Likely Key Driver of Colorectal Cancer Development and Progression
New targets are needed for agents that will more effectively treat colorectal cancer (CRC).
This study identifies a molecule that is probably a key driver of colorectal cancer.
The findings strongly
Ohio State Hematologist Recognized Nationally With Top 10 Clinical Research Achievement Award
COLUMBUS, Ohio – John C. Byrd, MD, has again received national scientific recognition for his translational research investigating use of the drug, ibrutinib, in the treatment of chronic lymphocytic l
Well-Known Cancer Gene NRAS Produces Five Variants, Study Finds
NRAS is one of the most studied cancer-related genes.
This study found that the gene produces five variants, not just one form as thought.
The finding might help improve drugs for cancers that i
Ohio State Recognizes Cancer ‘Champions’ at April 9 Awards Luncheon
Honorees selected from Ohio, Wisconsin and California
COLUMBUS, Ohio – Four individuals, a grassroots fundraising organization and major corporation will be recognized as cancer “champions” W
Innovative ‘False Pedicle’ Surgery Allows for Advanced Spinal/Pelvic Reconstruction
Ohio State team pioneers surgical technique to stabilize the spine and pelvis in complex bone cancer removal
COLUMBUS, Ohio – A multidisciplinary team at The Ohio State University Comprehensive C
Inhibition of CDK4 Might Promote Lymphoma Development and Progression
Inhibitors of CDK4, a protein that helps regulate the cell cycle, have been shown to inhibit cancer in some tumor types.
This new study found that inhibiting this molecule can cause genetic instabilit
Ohio State Partners with MedVax Technologies, Inc. to Bring a Cancer Peptide Vaccine to Patients
COLUMBUS, Ohio, and MIAMI, Florida – The Ohio State University, through the Ohio State Innovation Foundation, has signed an exclusive world-wide licensing agreement with MedVax Technologies, Inc., for
Study Identifies Possible New Target for Future Brain Cancer Drugs
Glioblastoma multiforme (GBM) is a lethal brain cancer that has an average survival of 15 months, so there is a critical need for new treatments.
This study found that GBM tumors that have high lev
Study of ‘Super Responder’ Reveals Possible New Gene Target for Lung Cancer
COLUMBUS, Ohio — A potential new gene mutation that might drive lung cancer development and growth has been identified by researchers at The Ohio State University Comprehensive Cancer Center – Arthur
Addition of Bevacizumab to the Treatment of Newly Diagnosed Glioblastoma Brain Tumors Does Not Extend Patients’ Lives
COLUMBUS, Ohio – Results from a randomized, phase 3 clinical trial conducted by the Radiation Therapy Oncology Group (RTOG) have shown that adding bevacizumab, a drug that inhibits the growth of blood
Ohio State Cancer Research Played a Significant Role in FDA Approval of Important New CLL Drug
COLUMBUS, Ohio – On Feb. 12, 2014, the U.S. Food and Drug Administration expanded the approved use of the drug ibrutinib to chronic lymphocytic leukemia (CLL).
Much of the clinical and basic-scienc
Study Reveals How Cancer Cells Thrive in Oxygen-Starved Tumors
Growing tumors often have areas of low oxygen, a condition called hypoxia.
How cancer cells survive and thrive under the stress of hypoxia is poorly understood.
This study shows how cancer cells cha
Yoga Can Lower Fatigue, Inflammation in Breast Cancer Survivors
In study, the more
women practiced, the better their results
COLUMBUS, Ohio -- Practicing yoga for as little as three months can reduce fatigue and lower in
Number of Cancer Stem Cells Might Not Predict Outcome in HPV-Related Oral Cancers
COLUMBUS, Ohio – New research from The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) suggests that it ma
Ohio State Awarded $11.3 Million for Thyroid Cancer Research
Prestigious National Cancer Institute SPORE grant third for cancer center
COLUMBUS, Ohio –The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital
AML Score That Combines Genetic and Epigenetic Changes Might Help Guide Therapy
Guido Marcucci, MD
Currently, treatments for adult acute myeloid leukemia (AML) are determined mainly using the chromosome changes and gene mutations present in AML cells.
In this study, researchers
Laboratory Study Confirms Target of Potent Chronic Leukemia Drug
Jennifer Woyach, MD
The experimental drug ibrutinib can be exceptionally effective in treating chronic leukemia, but it is unclear whether its primary target, a molecule called BTK, is important for
Tomato-Rich Diet Increases Hormone Linked to Reduced Breast Cancer Risk in Postmenopausal Women
COLUMBUS, Ohio – A tomato-rich diet could help protect at-risk postmenopausal women from breast cancer, according to new research from The Ohio State University Comprehensive Cancer Center – Arthur G.
Pelotonia Riders Pedal to a Record $19 Million for Cancer Research
Fundraising total of $61 million for first five years
COLUMBUS, Ohio - Pelotonia has announced record fundraising of more than $19 million for its 2013 ride.
From August 10-11, 2013, 6,723