COLUMBUS, Ohio – With the New Year often comes resolve to eat better, exercise more, lose weight and feel healthier. Yet for many, those well-intentioned resolutions fade away without any positive results.
Women struggling to lose weight may find the help they need to succeed by joining an ongoing study that examines the effects of a low-fat vs. a low-carbohydrate diet, plus exercise, on the risk of breast cancer. An additional 33 women are needed to join the clinical trial that began recruiting participants in August 2005 at the Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James).
Of the 27 women enrolled so far, all have lost weight, said Dr. Electra Paskett, associate director for population sciences at OSUCCC – James and principal investigator for the study.
Paskett, along with colleagues at Ohio State and Wake Forest University School of Medicine, are comparing the impact of each regimen on risk factors for breast cancer among pre-menopausal women at high risk of the disease because they are either overweight or obese.
Study participants must be at least 30 years old and have a body mass index (BMI) between 25 and 34. (BMI can be calculated by dividing weight in kilograms by height in meters, squared. For example, a woman who is 5’6” tall and weighs 156 has a BMI of 25.)
The women will be randomized into one of two diet plans, either a low-carbohydrate arm or a low-fat arm. All participants will be expected to exercise and meet one-on-one with a nutritionist on a monthly basis for 12 months to devise individualized diets. After that, nutritionists will follow up with phone calls to participants for an additional six months.
Participants will exercise regularly, mostly through walking, building up to 10,000 steps per day, measured by a pedometer, five times per week.
For more information, contact study coordinator Cecilia DeGraffinreid at 614-293-6917.
The Breast Cancer Research Foundation, founded by Evelyn H. Lauder, funds the study.
The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute is one of the nation’s leading centers for research on the prevention, detection, diagnosis and treatment of cancer. The OSU CCC – James encompasses six interdisciplinary research programs and includes more than 200 investigators who generate over $100 million annually in external funding. It is a founding member of the National Comprehensive Cancer Network, and OSU’s James Cancer Hospital is consistently ranked by U.S. News & World Report as one of America’s best cancer hospitals.# # #
Medical Center Communications