Ohio State Lung Cancer Researcher Receives Landon Foundation-AACR Innovator Award

April 12, 2013
Ohio State Lung Cancer Researcher Receives Landon Foundation AACR Innovator AwardCarbone

COLUMBUS, Ohio – Lung cancer expert David P. Carbone, M.D., Ph.D., who leads the thoracic oncology center at the Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC–James), received the Sixth Annual Landon Foundation – AACR INNOVATOR Award for International Collaboration in Cancer Research presented by the American Association for Cancer Research (AACR) and the Kirk A. and Dorothy P. Landon Foundation at the AACR Annual Meeting 2013, held in Washington, D.C., April 6-10.

The Award for International Collaboration in Cancer Research supports an established international cancer research collaboration involving institutes in multiple countries by supplementing existing funding and providing the means to facilitate travel, training in new techniques and disseminating scientific knowledge gained from the collaboration.

Carbone’s project, “Molecular Profile of Lung Adenocarcinoma in Brazil,” will be part of a continuing international collaboration between American-and Brazilian-based laboratories to better understand the molecular profile of lung cancer in the Brazilian population, which affected more than 27,000 Brazilians in 2012 alone.

A formal collaboration was established in October 2012, between The OSUCCC – James and the Brazilian National Cancer Institute to establish, in a comprehensive manner, the molecular profile of lung adenocarcinoma in Brazil. This collaboration is the foundation for the work proposed by Carbone.

Carbone and team will develop and validate a customized panel to genotype lung adenocarcinoma; they will then identify the frequency of genetic alterations in tumor specimens from 400 Brazilian patients with diagnosed lung adenocarcinoma. This information will be used to examine the occurrence of genetic changes to clinical and epidemiological characteristics and to also understand genetic clues about ancestry and their relation to genetic alterations in tumors.

This grant will support the continued study of the molecular profile of lung adenocarcinoma in Brazil. Ultimately, this study should provide genetic criteria to help treat Brazilian patients.

Founded in 1907, AACR is the world’s first and largest professional organization dedicated to advancing cancer research and its mission to prevent and cure cancer. AACR membership includes more than 34,000 laboratory, translational and clinical researchers; population scientists; other health care professionals; and cancer advocates residing in more than 90 countries. The AACR annual meeting attracts more than 17,000 attendees.

The Kirk A. and Dorothy P. Landon Foundation was created through a bequest from Mrs. Dorothy P. Landon whose intent, along with that of her late husband, Kirk A. Landon, was to dedicate a major portion of their estate to medical research, especially cancer research.

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute strives to create a cancer-free world by integrating scientific research with excellence in education and patient-centered care, a strategy that leads to better methods of prevention, detection and treatment. Ohio State is one of only 41 National Cancer Institute (NCI)-designated Comprehensive Cancer Centers and one of only seven centers funded by the NCI to conduct both phase I and phase II clinical trials. The NCI recently rated Ohio State’s cancer program as “exceptional,” the highest rating given by NCI survey teams. As the cancer program’s 228-bed adult patient-care component, The James is a “Top Hospital” as named by the Leapfrog Group and one of the top cancer hospitals in the nation as ranked by U.S. News & World Report.

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Contact: Eileen Scahill, Wexner Medical Center Public Affairs and Media Relations, 614-293-3737, or Eileen.Scahill@osumc.edu

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