Allogeneic

Physician Consultation Outpatient Visit

• Meet with transplant physician
  
• Review past medical history & treatment
  
• Discuss treatment options
  
• Discuss phases of transplantation
  
• Recommend additional treatment if indicated
  
• Initiate insurance verification, transplant benefits and approval
  
• Initiate donor search through siblings or National Marrow Donor Program (NMDP), if appropriate

Pre-transplant Evaluation for Recipient & Donor

Recipient:

• History & Physical examination
  
• Chest X-ray
  
• Electrocardiogram
  
• MUGA
  
• Pulmonary Function Tests (PFTs)
  
• Bloodwork, including viral titers
  
• Disease staging studies as needed (ie: CT scans, myeloma survey)
  
• Other tests as needed (ie: bone marrow aspirate & biopsy, lumbar puncture)
  
• Educational session to learn more about transplant
  
• Obtain insurance approval after pre-transplant evaluation completed

Donor:

• History and Physical
  
• Electrocardiogram
  
• Chest X-ray
  
• Bloodwork
  

Apheresis or Collection of Peripheral Blood Stem Cells (PBSCs) (if applicable)

• Donors will be given a medication (ie: Neupogen) by subcutaneous injection at home to move stems cells from the bone marrow into the blood
  
• Apheresis will begin approximately 5 days after Neupogen started
  
• Apheresis or donor stem cell collection is initiated on the same day of the infusion (Day 0)
  
• Apheresis is done everyday until sufficient PBSCs are collected
  
• Apheresis takes about 4-6 hours each day for about 1-2 days
  
• Donor will continue to take Neupogen injections until apheresis is completed
  

Transplant Hospital Admission

• Scheduled within about 30 days after completion of the pre-transplant evaluation
  
• Average of a 4 to 6 week hospital stay
  
• Central Venous Catheter (CVC) placement done on the day of admission (if appropriate)
  
• Preparative regimen will be given (chemotherapy with or without total body irradiation)
  
• Patient education handouts provided about what to expect
  
• Stem cells will be collected from the donor on day 0

Follow-up Care

• Outpatient clinic visits 2-3 times a week for about 2 - 3 months
  
• Follow-up care will be shared between the transplant center and the referring physician
  
• The time frame for disease staging post transplant may vary for specific diseases or research protocols