Clinical Research

Clinical research evaluates new laboratory findings that might advance cancer diagnosis, treatment or prevention in human beings. The evaluations are done using studies called clinical trials. The OSUCCC – James hundreds of clinical trials going on at anytime. Many are original studies initiated by OSUCCC – James investigators.

OSUCCC – James Clinical Research Strengths

  • The OSUCCC – James is one of only a few centers nationally funded by the NCI to conduct both phase I and phase II clinical trials.
  • OSUCCC – James investigators have decades of experience designing and conducting phase I and phase II cancer studies.
  • The new James Cancer Hospital and Solove Research Institute incorporates features designed to facilitate and encourage clinical research.
    • Each inpatient floor has translational research labs that bring physicians together with researchers to develop and deliver the most effective targeted therapies for patients
    • A dedicated early-phase Clinical Trials Unit offers a comforting patient environment with a staff highly experienced in safely conducting innovative, early-phase trials.
    • A state-of-the-art, good manufacturing processes Cellular Processing Laboratory supports the hospital’s 36-bed Blood and Marrow Transplant Unit
  • Precision Cancer Medicine at the new James uses advanced genomic technologies to identify the molecular changes that cause a patient’s cancer.
  • The OSUCCC – James is a comprehensive biomedical research campus with strong collaboration between investigators from the Colleges of Medicine, Pharmacy, Public Health, Nursing, Dentistry and Engineering.
  • Every clinical trial at the OSUCCC – James engages a team of scientists and includes near real-time pharmacokinetics, pharmacodynamics and pharmacogenomics correlative studies.
  • OSUCCC – James investigators collaborate extensively with other centers dedicated to experimental therapeutics.
  • After defining the safety profile and clinical characteristics of novel agents, OSUCCC – James investigators pursue development of strategic combination regimens.
  • OSUCCC – James trials often support new drug approvals by the FDA, while many others are hypothesis-driven therapeutic trials. These include trials for molecular-targeted therapies and genomic profiling of patient tumors, and trials to identify predictive biomarkers.
  • Original OSUCCC – James trials include basic scientists who help design the trial and contribute to the discovery of novel therapies.

Breast Cancer

Learn how bench-to-bedside clinical research is being conducted at the OSUCCC – James to improve prevention, detection & treatment of breast cancer.

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CNS Malignancy/Brain and Nervous System

Learn how bench-to-bedside clinical research is being conducted at the OSUCCC – James to improve prevention, detection & treatment of CNS Malignancies.

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Gastrointestinal Cancers

Learn how bench-to-bedside clinical research is being conducted at the OSUCCC – James to improve prevention, detection & treatment of Gastrointestinal Cancers.

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Genitourinary Cancers

Learn how bench-to-bedside clinical research is being conducted at the OSUCCC – James to improve prevention, detection & treatment of Genitourinary Cancers.

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Gynecologic Cancers

Learn how bench-to-bedside clinical research is being conducted at the OSUCCC – James to improve prevention, detection & treatment of Gynecologic Cancers.

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Head and Neck Cancers

Learn how bench-to-bedside clinical research is being conducted at the OSUCCC – James to improve prevention, detection & treatment of Head and Neck Cancers.

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Hematologic Malignancies

Learn how bench-to-bedside clinical research is being conducted at the OSUCCC – James to improve prevention, detection & treatment of Hematologic Malignancies.

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Melanoma

Learn how bench-to-bedside clinical research is being conducted at the OSUCCC – James to improve prevention, detection & treatment of Melanoma.

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Sarcoma

Learn how bench-to-bedside clinical research is being conducted at the OSUCCC – James to improve prevention, detection & treatment of Sarcomas.

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Thoracic

Learn how bench-to-bedside clinical research is being conducted at the OSUCCC – James to improve prevention, detection & treatment of Thoracic Cancers.

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Thyroid/Neuroendocrine

Learn how bench-to-bedside clinical research is being conducted at the OSUCCC – James to improve prevention, detection & treatment of Neuroendocrine Cancers.

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Nursing Research

Discover how nurses at the OSUCCC – James are propelling nursing cancer care forward through the integration of the latest data in the clinical setting.

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