Clay B Marsh, MD, Affiliate
Molecular Carcinogenesis and Chemoprevention
Pulmonary Fibrosis, inflammation, Idiopathic Pulmonary Fibrosis, Neovascularization, Pathologic, Anoxia, Neoplasms, Sepsis, Disease Models, Animal, Fibrosis, Lung Diseases, Interstitial
Focusing on the mechanisms underlying human health and disease, we have projects ranging from biomarker discovery using microRNA molecules to define genetic pathways and proteins important in tissue environments including breast cancer, lung cancer, lung fibrosis, and melanoma; cell biology studying the growth factors macrophage colony-stimulating factor (M-CSF) and granulocyte-macrophage colony-stimulating factor (GM-CSF) and mononuclear phagocytes in tissue environments including breast cancer, melanoma; stress pathways and human disease; and systems biology approaches to defining what networks underlie health. My laboratory is divided into five modules: 1) Systems biology/medicine genetics in human health and disease; 2) Signaling and cell survival/differentiation; 3) Lung repair and remodeling; 4) Angiogenesis in breast cancer and melanoma; 5) Stress and depression in human health, aging and disease; 6) Translational Research in pulmonary fibrosis and breast cancer.