Katsumi Kitagawa, PhD, Affiliate

Katsumi Kitagawa

College

College of Medicine

Department/Division

Pediatrics

Academic Title

Assoc Professor

Research Program

Molecular Biology and Cancer Genetics

Research Interest

Plant Diseases, DNA Breaks, Double-Stranded

Dr. Kitagawa's research involves the role that the spindle checkpoint plays in tumor development. Mutations in genes required for kinetochore function and mitotic checkpoint surveillance possibly contribute development of cancer. His lab is employing a series of genetic and biochemical strategies to identify additional interacting gene products, regulators, and potential substrates of Sgt1/Skp1/Hsp90 action in yeast and vertebrates. In studies with human cells, they have found a novel mechanism by which 17-AAG (an Hsp90 inhibitor and a novel anti-cancer drug) inhibits cell proliferation and provide the first evidence of HSP90 being required for assembly of kinetochore protein complexes in humans.


Education and Background

Fellowship

  • Postdoctoral Fellow, Centre for Molecular Medicine and Therapeutics

    University of British Columbia

    Vancouver, BC (CANADA)

  • Postdoctoral Fellow, Molecular Biology and Genetics

    The Johns Hopkins University

    Baltimore, MD (USA)

  • Research Fellow, Department of Molecular Biology

    Nagoya University

    Chikusa-ku, NAGOYA (JAPAN)

Office Location

WA5014 Center for Childhood Cancer

700 Children's Drive, Columbus, OH 43205


614-355-2632

614-722-5895



Publications

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