Mark D Wewers, MD
College of Medicine
Molecular Carcinogenesis and Chemoprevention
alpha 1-Antitrypsin Deficiency, Inflammation, Pulmonary Emphysema, Sepsis, Emphysema, Respiratory Distress Syndrome, Adult, Infection, HIV Infections, Multiple Organ Failure, Burkholderia Infections
Dr. Wewer’s research focuses on host defense against pathogens, particularly relevant to the lung and critical to survival His lab is interested in understanding the role of proteins that regulate the activation of the intracellular enzyme, caspase-1. This work is relevant to understanding how the lung and circulating mononuclear phagocytes are capable of sensing danger from pathogens and responding with robuts inflammation centered around IL-1.