Qi-En Wang, PhD

Qi-En Wang

College

College of Medicine

Division/Department

Radiology

Academic Title

Asst Professor

Research Program

Molecular Carcinogenesis and Chemoprevention

Research Interest

DNA Damage, Ovarian Neoplasms, Li-Fraumeni Syndrome, Xeroderma Pigmentosum, Adenocarcinoma, Carcinoma, Papillary, Glioblastoma

The focus of Dr. Wang's research is on the regulation of nucleotide excision repair (NER), one of the DNA repair pathways, and the connection of DNA repair to cancer therapy. Dr. Wang's research strives to explore the mechanism of NER, and finally find means to prevent cancer initiation via improving normal cells’ capability to repair DNA damage or to enhance the efficacy of cancer therapy through inhibiting the repair of DNA damage induced by chemotherapeutic agents and radiotherapy. Three separate projects are being pursued: Chromatin modification and remodeling in NER following UV or cisplatin treatment; Protein posttranslational modifications and degradation in DNA repair; and Role of NER proteins in chemotherapeutic agents-induced apoptosis.


Education and Background

Office Locations

736 Biomedical Research Tower

460 W 12th Avenue, Columbus, Ohio 43210


614-292-9114



Publications

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