Robert A DiSilvestro, PhD

Robert DiSilvestro

College

College of Education & Human Ecology

Division/Department

Human Nutrition

Academic Title

Professor

Research Program

Molecular Carcinogenesis and Chemoprevention

Research Interest

Oxidative Stress, Acute-Phase Reaction, Wounds and Injuries, Drug-Induced Liver Injury, Attention Deficit Disorder with Hyperactivity, Diabetes Mellitus, Type 2, Carbon Tetrachloride Poisoning, Cardiovascular Diseases, Anemia, Osteoporosis

Phytochemicals are food components from plants that are not strictly required for normal function, but can have health promoting properties.  These health promoting properties can include reducing cancer risk.  Examples of the mechanisms include antioxidant/anti-inflammatory actions, boosting the immune system, strengthening connective tissue, and raising internal production of carcinogen metabolizing enzymes.  My research considers the effects of certain phytochemicals on these processes.  A current project examines green tea phytochemicals in relationship to various anti-cancer defense mechanisms in pulmonary bronchoalveolar lavage fluid from humans.  Certain phytochemicals can work through the body’s own antioxidant/anti-inflammatory molecules.  Some of these molecules, such as the superoxide dismutase enzymes, require minerals for activity.  Thus, my research looks at how phytochemicals and minerals can work together.


Education and Background

Office Locations

345 Campbell Hall

1787 Neil Avenue, Columbus, Ohio 43210


614-292-6848

614-292-8880



Publications

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