Tatiana M Oberyszyn, PhD
College of Medicine
Molecular Carcinogenesis and Chemoprevention
Skin Neoplasms, Neoplasms, Radiation-Induced, inflammation, Neoplasms, Carcinoma, Squamous Cell, Dermatitis, Disease Models, Animal, Papilloma, DNA Damage, Cell Transformation, Neoplastic
Studies in the Oberyszyn skin carcinogenesis laboratory are designed to increase our understanding of the function of biological mediators including prostaglandins, cytokines and reactive oxygen intermediates during Ultraviolet Light induced Squamous Cell Carcinoma development. Current studies are focused on understanding the differences in male and female skin that contribute to men developing significantly more skin cancer. We are also trying to understand the link between therapeutic or disease induced immunosuppression and the staggering increase in development of non-melanoma skin cancer. In addition we are evaluating both topically applied as well as orally delivered natural compounds such as black raspberry extracts and tomatoes as potential chemopreventive and chemotherapeutic agents.