Research conducted by the Roychowdhury Laboratory Team includes basic cancer research and translational cancer genomics.

We are a multidisciplinary group with Team Members who have expertise in diverse fields including cancer genomics, computational biology/computer science, cancer biology, drug development, molecular diagnostics and medical oncology.

Basic cancer research is about the core principles of cancer, while translational cancer research is about using this knowledge to take care of patients through clinical trials. Together, as a multidisciplinary team, we:

  • Evaluate and care for patients through clinical trials
  • Study the genetics of cancer using next generation sequencing
  • Match patients to new smart drugs in trials
  • Evaluate the benefit from such therapies
  • Study how drugs affect the cancer
  • Strive to develop rational combination treatments for patients

CCC Members

Michael Caligiuri, MD

Michael A. Caligiuri, MD, is director of The Ohio State University Comprehensive Cancer Center (OSUCCC), where he is also a member of the Leukemia Research Program.

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Don Benson, MD, PhD

Our laboratory and clinical research programs seek to develop novel treatments for cancer that harness and enhance the immune system’s ability to detect and kill cancer cells. Natural killer cells, one type of immune cell in the body, are capable of killing cancer cells and much of the research.

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Anjali Mishra, PhD

Dr. Mishra's research has shown stage-related ‘interleukin-15 (IL-15)’ mRNA and protein over-expression in lesional skin and circulating tumor cells of CTCL patients. Using IL-15 transgenic (tg) mice, Dr. Mishra's lab has characterized an animal model of spontaneous epidermotropic T-cell lymphoma.

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Jianhua Yu, PhD

Dr. Yu's research interests include Immuno-cellular therapy, blood and marrow transplantation, NK cell biology, gene regulation and cell signaling in immune response and malignant transformation

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Researchers and Lab Staff

Donna Bucci, BS

Donna serves as Manager of the Caligiuri Research Lab, HEME Biorepositories and OSU Leukemia Tissue Bank Shared Resource.

Wing Chan, PhD

Wing recently joined the Caligiuri Lab as a Post-Doctoral Researcher. He came to the lab from St. Jude’s Research Center. Wing works with the NK Cell Development and Oncolytic Virus Research Teams.

Li Chen, MB

Li is a Research Associate in the Caligiuri Lab. Li works with the NK Cell Development team.

HongSheng Dai, PhD

HongSheng is a Post-Doctoral Fellow and recipient of a Pelotonia Fellowship for 2014-2016. HongSheng works with the NK Cell Development and Oncolytic Virus Research Teams.

Christopher Manring, BA

Chris is the Research Data Manager for the HEME Biorepository and OSU Leukemia Tissue Bank Shared Resource.

Charlene Mao, MS

Charlene serves as Research Associate and Flow Cytometry Specialist in the Caligiuri Lab. Charlene plays a key role in the lab providing training and support for all research teams.

Kathleen McConnell, BS

Kathleen serves as Research Assistant and Research Animal Colony Specialist in the Caligiuri Lab. Kathleen plays a key role in the lab providing training and support for all research teams.

Bethany Mundy-Bosse, PhD

Bethany studies Natural Killer (NK) cell development related to Acute Myeloid Leukemia and is a recipient of the prestigious T32 Post-Doctoral Fellowship award for training in Oncology. Bethany presented a poster at the Society for Natural Immunity Meeting in Montreal, May 2015.

Il-Kyoo Park, PhD

Il-Kyoo studies NK cell development related to Acute Myeloid Leukemia and is a recipient of the prestigious T32 Post-Doctoral Fellowship award for training in Oncology.

Victoria Sellers, BS

Victoria serves as Research Assistant and Research Animal Colony Specialist in the Caligiuri Lab. Victoria primarily supports NK Cell Development projects.

Robin Taxier, BS

Robin is Research Technologist for the OSU Leukemia Tissue Bank Shared Resource and Alliance HEME Biorepository.

Wacharaphon Vonchucherd, BS

Wacharaphon is the Senior Research Technologist for the OSU Leukemia Tissue Bank Shared Resource and Alliance HEME Biorepository.

Jing Wen, MB

Jing is a Research Associate with the Mishra Lab research team.

Max Yano, AB

Max is Research Aide with the Mishra Lab research team. Max has been accepted to the OSU School of Medicine.

Students

Elshafa Ahmed , CVM, MPH

Elshafa is currently pursuing a PhD in Veterinary Biosciences; Dr. Caligiuri is her Doctoral Advisor. She is studying the development of vaccine for a specific type of tumor relevant to post organ transplant disease.

Stephen Bergin, BS

Stephen is enrolled in the MD/PhD program, OSU School of Medicine. Stephen works with the NK Cell Development and Oncolytic Virus Research Teams.

Daniel Brook

Daniel is an undergraduate student at OSU and Research Volunteer in the Caligiuri lab.

Billy Carson

Billy is an undergraduate student at OSU and a Wells Family Scholar for 2014.

Taylor Fisher

Taylor is an undergraduate student at OSU and a Student Clinical Data Assistant for the OSU Leukemia Tissue Bank Shared Resource.

Erin Glankler

Erin is an undergraduate student at OSU and a Research Volunteer working in the Wing Chan lab.

Nathaniel Griffin

Nathaniel is an OSU Undergraduate Research Volunteer working with Hongsheng Dai.

Evan Gutter

Evan is an undergraduate student at OSU and a Research Volunteer working in the Biorepository Central Processing Lab.

Sonya Kwiatkowski

Sonya is an Undergraduate Research Assistant. Sonya works with the Mishra Lab research team. Sonya has been accepted to the OSU School of Medicine.

Ayako McGregor

Ayako is an undergraduate student at OSU and a Student Research Assistant working in the Biorepository Central Processing Lab.

Mary Nemer

Mary is an OSU Undergraduate Research Volunteer working with Aaron Victor. She has been awarded a summer research fellowship by Ohio State's Undergraduate Research Office.

Steven Scoville, BS

Steven is enrolled in the MD/PhD program, OSU School of Medicine, and part of the Medical Scientist Training Program. Steven works with the NK Cell Development team. Recipient of F30 Ruth L. Kirschstein National Research Service Award from the NIH. Steven also presented a poster and the ASCI/AAP meeting in Paris in April 2015. Steven presented a poster at the Society for Natural Immunity Meeting in Montreal, May 2015.

Kevin Stephenoff

Kevin is an undergraduate student at OSU and Student Research Assistant working in the Biorepository Central Processing Lab.

Aaron Victor, BS

Aaron is enrolled MD/PhD program, OSU School of Medicine. Aaron works with the NK Development team.

Michael Zhang

Michael is an undergraduate research volunteer working with Steven Scoville. He has been awarded a summer research fellowship by Ohio State's Undergraduate Research Office.

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