Pelotonia Fellowship Symposium

The sharing of ideas and the development of collaborations are two cornerstones of the Pelotonia Fellowship Program. To this end, a yearly scientific symposium brings together awardees, their mentors, world class scientists and leaders from the community.

The 2014 Pelotonia Fellowship Symposium featured the following world renowned scientists:

Carlos Arteaga, MD
Professor of Medicine and Cancer Biology
Associate Director for Clinical Research
Director Center for Cancer Targeted Therapies
Director Breast Cancer Program
Vanderbilt-Ingram Cancer Center
TOPIC: PI3K Pathway in Breast Cancer: Role in Tumor Progression and as a Therapeutic Target

Guillermina (Gigi) Lozano, PhD
Chair and Professor
Department of Genetics
University of Texas MD Anderson Cancer Center
TOPIC: Dissecting the p53 Pathway in Vivo

David Beach, PhD, FRS
Professor of Stem Cell Research
Blizard Institute
TOPIC: The Cell Cycle and Cancer: Back to the Future

The following Pelotonia Fellows were featured at the 2014 Symposium:

Adrienne Dorrance, PhD
TOPIC: Targeting Leukemia Stem Cells with AntagomiR-126 Nanoparticles in Acute Myeloid Leukemia

Markus Harrigan
TOPIC: A Genome-wide RNAi Screen for Novel Stromal-derived Oncogenic Signals in the Tumor Microenvironment

Samantha King
TOPIC: Soy Isoflavones and Metabolites as Immunomodulators for Cancer

Ta-Ming Liu, PhD 
TOPIC: Administration of Kinase Targeting Therapies in Chronic Lymphocytic Leukemia: The Pre-Clinical Development of OSU-T315

Jason Pitaressi 
TOPIC: Genetic Ablation of Smoothened in Tumor Associated Fibroblasts Promotes Pancreatic Cancer Initiation

Mark Rudolph 
TOPIC: Combined Targeting of EGFR and Hedgehog Signaliing Pathway to Overcome Endocrine Resistance

Lawrence Shirley, MD 
TOPIC: Integrin-Linked Kinase Overexpression in the Dysregulated Stroma of Pancreatic Cancer and the Impact on Patient Survival

Andrew Stiff 
TOPIC: HDACi Increase the Anti-Myeloma Activity of Reolysin Through the Up-Regulation of the Reovirus Receptor JAM-1

Ramon Sun, PhD
TOPIC: Glutamine Metabolism is Required for Cell Proliferation in Hypoxia and Growth of Model Tumors

Jingyan Wu
TOPIC: Genome-Wide Screen Identifies Pathways That Govern tRNA Splicing and Intron Turnover in Saccharomyces Cerevisiae

Previous Invited External Speakers


Jon Aster, MD, PhD
Harvard Medical School
TOPIC: Targeting Notch in Cancer: Challenges and Opportunities

Stephen Elledge, PhD
Harvard Medical School
TOPIC: Genetic Approaches to Cancer

Michele Pagano, MD, PhD
New York University School of Medicine
TOPIC: Ubiquitin Ligases Regulate Modular Elements of Molecular Machines


David E. Fisher, MD, PhD
Harvard Medical School
TOPIC: Signaling pathways in melanocytes and melanoma development

Martine F. Roussel, PhD
Member, St. Jude Children's Research Hospital Faculty
TOPIC: Molecular networks and cell of origin of pediatric medulloblastoma

Charles J. Sherr, MD, PhD
St. Jude Children's Research Hospital
TOPIC: The INK4-ARF tumor suppressor: regulation of cellular self-renewal


Judith Campisi, PhD
Lawrence Berkeley National Laboratory
TOPIC: Cancer and Aging: Rival Demons?”

Ross Levine, MD
Memorial Sloan-Kettering Cancer Center
TOPIC: Role of Mutations in Epigenetic Modifiers in Myeloid Malignancies

John H. J. Petrini, PhD
Memorial Sloan-Kettering Cancer Center
TOPIC: Genetic Analysis of Chromosome Break Metabolism

Previous Invited Pelotonia Fellows


Dinesh Ahirwar, PhD
TOPIC: Recombinant Slit2 protein inhibits breast cancer growth by inhibiting macrophages

Kyle Beckwith
TOPIC: A novel mouse model of human CD37-positive leukemia highlights the therapeutic potential of IMGN529

Ed Briercheck, PhD
TOPIC: Maximum natural killer cell cytolytic activity  requires optimum PTEN expression

Cai Chen
TOPIC: Transcriptome-wide RNA editing can be used in cancer subtype discrimination

Aishwarya Jacob
TOPIC: MDM2-ALT1: dual role as a suppressor and a driver of oncogenesis

Ben Hemmelgarn
TOPIC: Dissecting the Intersection Between the Rb/E2F and Myc Pathways in vivo

Nikola Kovinich, PhD
TOPIC: New Frontiers in the Chemical Arsenal Against Cancer: Combining Modules of Semi-Synthesis and Synthetic Biology

I-Ju Lee
TOPIC: Regulation of SPB assembly and cytokinesis by the centrin-binding protein Sfi1 in fission yeast

Kinshuk Mitra
TOPIC: Towards a more perfect separation: Leveraging microfluidics for marker capture and characterization

Ryan Reyes
TOPIC: miR-23a: A Key Metabolic Regulator in Hepatocellular Carcinoma

Rachel Zielinski
TOPIC: Targeting Cellular Biomechanics to Modulate Cancer Cell Motility and Tumor Morphogenesis


Christina Austin
TOPIC: Essential Roles and Functional Redundancy of EGFR Ligands in Drosophila Development

Kyle Beckwith
TOPIC: Human CD37 mouse models for evaluation of targeted therapeutics for B cell malignancies

Hemant Bid, PhD
TOPIC: Targeting the IGF-axis as a strategy to suppress tumor angiogenesis

Ann Kathrin Eisfeld, MD
TOPIC: miR-3151 interplays with its host gene BAALC and independently impacts on outcome of patients with cytogenetically normal acute myeloid leukemia

Nancy Engelmann Moran, PhD
TOPIC: Development of a 13C-enriched lycopene for human metabolic studies and assessment of anti-cancer mechanisms of action

Patrick Grierson
TOPIC: The BLM helicase senses nucleolar stress as a component of an RNA polymerase I-associated complex

Daniel Kiss, PhD
TOPIC: Cytoplasmic mRNA Recapping, P-Bodies, and Capping Inhibited mRNAs

George Koutras
TOPIC: Evaluation of a mucoadhesive fenretinide patch for local intraoral delivery: A strategy to re-introduce fenretinide for oral cancer chemoprevention

Huayang Liu
TOPIC: A Genome-wide RNAi Screen to Identify Novel Regulators of the Tumor Microenvironment

James Phelan
TOPIC: Growth factor independence 1 (Gfi1) antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemia

Kathryn Takamura
TOPIC: Dextran Vesicles: A Versatile Renewable Drug Carrier for Camptothecin Loading and Delivery into Cells

Salene Wu
TOPIC: Anxiety, Worry, and Inflammation in Women with Recurrent Cancer


Enrico Caserta, PhD
TOPIC: Tumor Suppression Functions of PTEN in Stromal Cells

Hsiao-Ching Chuang
TOPIC: Combining poly-(ADP-ribose) polymerase (PARP) inhibitors with Energy Restriction-Mimetic Agents (ERMAs) as a novel therapeutic approach for triple-negative breast cancer

Nripesh Dhungel
TOPIC: tRNA splicing endonuclease: Investigating novel functions

Jonathan Lee
TOPIC: A Genome-Wide Screening of Drosophila melanogaster to Identify Endoreduplication Specific Genes

Dustin Gable
TOPIC: Ets1 as a Potential Target of MicroRNA-1 in Cutaneous Squamous Cell Carcinoma

April Gocha
TOPIC: BRCA1 Interactions with RecQ-like Helicases in the Control of Telomere Maintenance

Kevin Kauffman
TOPIC: Pulmonary Polymeric Microparticles for the Treatment of Lung Cancer

Jiang Li, PhD
TOPIC: Molecular Mechanism of DNA Repair by (6–4) Photolyase

Parvathi Ranganathan, PhD
TOPIC: Regulation of Acute Graft-Versus-Host Disease by microRNA-155

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