Molecular Biology / Cancer Genetics Clinical Trials

Protocol No.PITitle
OSU-0107Doreen AgneseProspective Cohort Study of BRCA1 & BRCA2 Carriers
OSU-10129Dawn AllainThe Value of Genetic Counselors in Genetic Testing for Hereditary Breast-Ovarian Cancer
OSU-12194Leslie AndritsosClinical Research in Hairy Cell Leukemia: Surveillance and Documentation of Clinical Outcomes in a Rare Form of Adult Leukemia
OSU-06056Sanford BarskyUse and Validation of Virtual Algorithms on TMA and Individual Microscope Slides to Detect Cancer Cells and Quantitate Immunocytochemical Staining for Select Nuclear, Cytoplasmic and Membrane Antigens.
OSU-06016Sanford BarskyThe Bone marrow Stem Cell Origin of Solid Cancers in Humans and Transgenic Mice.
OSU-06017Sanford BarskyClues to the Stem Cell Origin of Human Cancers by Studying a Registry of Organ Transplant Recipients.
CALGB-8461Clara BloomfieldCytogenetic Studies in Acute Leukemia [Dr. Clara Bloomfield, National Study Chair]
OSU-05019Michael CaligiuriAssessment of Aberrant Expression of Leukemic Markers in Normal CD34+ Hematopoietic Precursors.
OSU-05061Michael CaligiuriMolecular Studies in Acute Myeloid Leukemia
OSU-1997CO194Michael CaligiuriOSUCCC Leukemia Tissue Bank
OSU-07030William CarsonAnalysis of Micro-RNA Species in Melanoma.
OSU-13114William CarsonA Storage Facility for Tissues Obtained from Patients with Malignant Melanoma.
OSU-12140Arnab ChakravartiMolecular markers of prostate carcinoma
OSU-06036Frederick DavidorfGenetics of Hereditary Uveal Melanoma.
OSU-0358Frederick DavidorfMolecular Genetic Profiling of Uveal Melanomas
OSU-9812Albert de la ChapelleA Strategy to Search for Genes Predisposing to Papillary Carcinoma of the Thyroid When Mutated
OSU-9952Albert de la ChapelleStorage of DNA/RNA for the Discovery of Genes Involved in Cancer Predisposition - A Tissue Collection Study
OSU-05090Albert de la ChapelleStorage of Biological Material for the Discovery and Characterization of Genes Involved in Hereditary Disease Predisposition.
OSU-06005Albert de la ChapelleCharacterization of Mutations in the PMS2 Gene in Samples from the Human Cancer genetics Sample Bank.
OSU-07013Albert de la ChapelleThe Identification of Predisposing Genes in Hyperplastic Polyposis (HPP)
OSU-07087Albert de la ChapelleCharacterization of Potential Susceptibility Genes in Chronic Lymphocytic Leukemia (CLL)
OSU-09060Albert de la ChapelleEvaluation of In Vivo and In Vitro Pharmacology and Toxicology of Preventive Agents by Proteomics Using Human Mutant Cells from Dominantly Heritable Cancers: Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer (HNPCC)
OSU-11002Yvonne EfeberaAssessment of MicroRNA Expression in Acute Graft-versus-Host Disease
OSU-10130James ElderNIH 1308: The Cancer Genome Atlas Patient Enrollment and Specimen Qualification Criteria Grade II-IV Gliomas
OSU-0449Denis GuttridgeAssessment of NFkB in Muscle Wasting Associated with Cancer-Induced Cachexia
OSU-05059Tsonwin HaiInvestigation of a Potential New Oncogene
OSU-10115Craig HofmeisterBuckeye Surveillance, Contact, and Research for Multiple Myeloma and Amyloidosis
OSU-06032Richard KloosThe Endocrine Neoplasia Repository (ENR).
OSU-0456Jas LangTissue Procurement and Database for the Study of Molecular Events in Primary, Recurrent, and Metastatic Squamous Cell Carcinoma of the Head and Neck.
OSU-12042Greg LesinskiThe Effect of a Soy Bread Diet Intervention on Immune Function in Men with Prostate Cancer
OSU-07110Amir MortazaviOptimizing Human Urine Protein Extraction
OSU-12053Greg OttersonA Randomized Phase II Trial of Erlotinib Alone or In Combination with Bevacizumab in Patients With Non-Small Cell Lung Cancer and Activating Epidermal Growth Factor Receptor Mutations
OSU-12184Greg OttersonLung Cancer Mutation Consortium Protocol
CALGB-151108Greg OttersonCORRELATIVE IMAGING ANALYSIS OF CALGB 30406: ERLOTINIB THERAPY IN LUNG CANCER AS A MODEL FOR THE DEVELOPMENT OF BIOLOGICALLY MEANINGFUL RESPONSE METRICS
OSU-06083Christoph PlassThe Identification of Predisposing Genes in Chronic Lymphocytic Leukemia (CLL).
OSU-14032Raphael PollockEstablishing Cell Lines and Examining Tumor and Peripheral Blood Biological Markers from Human Sarcoma
OSU-13053Sameek RoychowdhuryPrecision Cancer Medicine for Advanced Cancer Through High-throughput Sequencing
OSU-11127Leigha Senter-JamiesonThe impact of pregnancy during and after breast cancer on survival in carriers of BRCA1 and BRCA2 mutations
OSU-14072Kate Shane-CarsonINHERIT EGFR - Investigating Hereditary Risk from T790M: A multi-centered study to identify and characterize individuals carrying germline EGFR mutations
OSU-07088Charles ShapiroThe Columbus Breast Cancer Tissue Bank
OSU-06070Stephan TannerGenetic Classification of Juvenile Cobalamin Deficiency.
OSU-07014Amanda TolandGenetic Modifiers of Breast and Ovarian Cancer Risk
OSU-05102Amanda TolandIdentification of Human Cancer Susceptibility & Resistance Genes.
OSU-05078Amanda TolandGenomic Analysis of Squamous Cell Carcinoma
OSU-05082Amanda TolandVariants in High Risk Breast Cancer Genes and Contribution to Cancer Risk.
OSU-05092James Van BrocklynThe Role Shingosine Kinase in Astrocytic Gliomas.
OSU-12020Robert WesolowskiMINT I Multi-Institutional Neo-adjuvant Therapy MammaPrint project I
CALGB-40903Lisa YeePHASE II STUDY OF NEOADJUVANT LETROZOLE FOR POSTMENOPAUSAL WOMEN WITH ESTROGEN RECEPTOR POSITIVE DUCTAL CARCINOMA IN SITU [DCIS)

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 300 W. 10th Ave. Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu