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Matthew D. Ringel MD


Matthew D. Ringel MD
ProfessorCollege of Medicinematthew.ringel@osumc.edu
445D McCampbell Hall 1581 Dodd Drive Columbus OH 43210
Phone:614-292-3800Fax: 614-247-1622
  • Molecular Biology and Cancer Genetics
  • Administrative

Current Publications

  • Ma Y, McCarty SK, Kapuriya NP, Brendel VJ, Wang C, Zhang X, Jarjoura D, Saji M, Chen CS, Ringel MDDevelopment of p21 Activated Kinase-targeted Multikinase Inhibitors that Inhibit Thyroid Cancer Cell Migration.J Clin Endocrinol Metab in press 5/24/2013
  • Liyanarachchi S, Wojcicka A, Li W, Czetwertynska M, Stachlewska E, Nagy R, Hoag K, Wen B, Ploski R, Ringel MD, Kozłowicz-Gudzinska I, Gierlikowski W, Jazdzewski K, He H, de la Chapelle ACumulative Risk Impact of Five Genetic Variants Associated With Papillary Thyroid Carcinoma.Thyroid in press 5/9/2013
  • He H, Bronisz A, Liyanarachchi S, Nagy R, Li W, Huang Y, Akagi K, Saji M, Kula D, Wojcicka A, Sebastian N, Wen B, Puch Z, Kalemba M, Stachlewska E, Czetwertynska M, Dlugosinska J, Dymecka K, Ploski R, Krawczyk M, Morrison PJ, Ringel MD, Kloos RT, Jazdzewski K, Symer DE, Vieland VJ, Ostrowski M, Jarzab B, de la Chapelle ASRGAP1 Is a Candidate Gene for Papillary Thyroid Carcinoma Susceptibility.J Clin Endocrinol Metab 98(5) E973-80 5/1/2013
  • Kloos RT, Valle LA, Sipos JA, Porter K, Ringel MD, Khawaja R, Gorodeski Baskin RLIn thyroidectomized patients with thyroid cancer, a serum thyrotropin of 30 μU/mL after thyroxine withdrawal is not always adequate for detecting an elevated stimulated serum thyroglobulin.Thyroid 23(2) 185-93 2/1/2013
  • He X, Saji M, Radhakrishnan D, Romigh T, Ngeow J, Yu Q, Wang Y, Ringel MD, Eng CPTEN lipid phosphatase activity and proper subcellular localization are necessary and sufficient for down-regulating AKT phosphorylation in the nucleus in Cowden syndrome.J Clin Endocrinol Metab 97(11) E2179-87 11/1/2012
  • Liu YY, Zhang X, Ringel MD, Jhiang SModulation of sodium iodide symporter expression and function by LY294002, Akti-1/2 and Rapamycin in thyroid cells.Endocr Relat Cancer 19(3) 291-304 6/1/2012
  • Koh YW, Shah MH, Agarwal K, McCarty SK, Koo BS, Brendel VJ, Wang C, Porter K, Jarjoura D, Saji M, Ringel MDSorafenib and Mek inhibition is synergistic in medullary thyroid carcinoma in vitro.Endocr Relat Cancer 19(1) 29-38 2/1/2012
  • Gudmundsson J, Sulem P, Gudbjartsson DF, Jonasson JG, Masson G, He H, Jonasdottir A, Sigurdsson A, Stacey SN, Johannsdottir H, Th Helgadottir H, Li W, Nagy R, Ringel MD, Kloos RT, de Visser MC, Plantinga TS, den Heijer M, Aguillo E, Panadero A, Prats E, Garcia-Castaño A, De Juan A, Rivera F, Walters GB, Bjarnason H, Tryggvadottir L, Eyjolfsson GI, Bjornsdottir US, Holm H, Olafsson I, Kristjansson K, Kristvinsson H, T Magnusson O, Thorleifsson G, Gulcher JR, Kong A, Kiemeney LA, Jonsson T, Hjartarson H, Mayordomo JI, Netea-Maier RT, de la Chapelle A, Hrafnkelsson J, Thorsteinsdottir U, Rafnar T, Stefansson KDiscovery of common variants associated with low TSH levels and thyroid cancer risk.Nat Genet 44(3) 319-22 1/22/2012
  • Ni Y, He X, Chen J, Moline J, Mester J, Orloff MS, Ringel MD, Eng CGermline SDHx variants modify breast and thyroid cancer risks in Cowden and Cowden-like syndrome via FAD/NAD-dependant destabilization of p53.Hum Mol Genet 21(2) 300-10 1/15/2012
  • Ni Y, He X, Chen J, Moline J, Mester J, Orloff MS, Ringel MD, Eng CGermline SDHx variants modify breast and thyroid cancer risks in Cowden and Cowden-like syndrome via FAD/NAD-dependant destabilization of p53.Hum Mol Genet 21(2) 300-10 1/15/2012
  • Shen R, Liyanarachchi S, Li W, Wakely PE, Saji M, Huang J, Nagy R, Farrell T, Ringel MD, de la Chapelle A, Kloos RT, He HMicroRNA signature in thyroid fine needle aspiration cytology applied to "atypia of undetermined significance" cases.Thyroid 22(1) 9-16 1/1/2012
  • Jendrzejewski J, Tomsic J, Lozanski G, Labanowska J, He H, Liyanarachchi S, Nagy R, Ringel MD, Kloos RT, Heerema NA, de la Chapelle ATelomere length and telomerase reverse transcriptase gene copy number in patients with papillary thyroid carcinoma.J Clin Endocrinol Metab 96(11) E1876-80 11/1/2011
  • Saji M, Narahara K, McCarty SK, Vasko VV, La Perle KM, Porter K, Jarjoura D, Lu C, Cheng SY, Ringel MDAkt1 deficiency delays tumor progression, vascular invasion, and distant metastasis in a murine model of thyroid cancer.Oncogene 30(42) 4307-15 10/20/2011
  • Arab K, Smith LT, Gast A, Weichenhan D, Huang J, Claus R, Hielscher T, Espinosa AV, Ringel MD, Morrison CD, Schadendorf D, Kumar R, Plass CEpigenetic deregulation of TCF21 inhibits metastasis suppressor KISS1 in metastatic melanoma.Carcinogenesis 32(10) 1467-73 10/1/2011
  • You J, Wang L, Saji M, Olesik SV, Ringel MD, Lucas DM, Byrd JC, Freitas MAHigh-sensitivity TFA-free LC-MS for profiling histones.Proteomics 11(16) 3326-34 8/1/2011