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Sung Ok. Yoon PhD


Sung Ok. Yoon PhD
Assoc ProfessorCollege of Medicineyoon.84@osu.edu
184 Rightmire Hall 1060 Carmack Road Columbus OH 43210
Phone:614-292-8542Fax: 614-292-5379
  • Molecular Biology and Cancer Genetics

General Research Interest

JNK signaling, polarity in glioma invasion, Alzheimer's disease

Research Description

The long-term goal of the lab is to understand how the balance between cell survival and death is maintained in the adult nervous system.  Currently, we are focusing on the role of stress kinase, JNK signaling, under pathological conditions.

Transinstitutional Work

In collaboration with Drs. M. Viapiano and C.H. Kwon, we are investigating the role of small GTPase and polarity proteins in glioma invasion. 

Current Publications

  • Tep C, Kim ML, Opincariu LI, Limpert AS, Chan JR, Appel B, Carter BD, Yoon SOBrain-derived neurotrophic factor (BDNF) induces polarized signaling of small GTPase (Rac1) protein at the onset of Schwann cell myelination through partitioning-defective 3 (Par3) protein.J Biol Chem 287(2) 1600-8 1/6/2012
  • Kim TH, Song J, Alcantara Llaguno SR, Murnan E, Liyanarachchi S, Palanichamy K, Yi JY, Viapiano MS, Nakano I, Yoon SO, Wu H, Parada LF, Kwon CSuppression of peroxiredoxin 4 in glioblastoma cells increases apoptosis and reduces tumor growth.PLoS One 7(8) e42818 1/1/2012