General Research Interest
Employing advanced enzymology to investigate DNA polymerases, kinases, and proteases.Research Description
Three major research projects in the Suo laboratory: i) using pre-steady state kinetic techniques (rapid chemical quench flow and stopped flow) and single molecule methods to elucidate kinetic mechanisms for DNA polymerases, kinases, and proteases; ii) develop small molecules to inhibit hepatitis C infections; and iii) investigate the efficacy and toxicity of antiviral and anticancer nucleoside analogs.Transinstitutional Work
We have collaborated with the following groups in the past several years: Dr. Hong Ling, an X-ray Crystallographer at University of Western Ontario, Canada; Dr. John-Stephen Taylor, a chemist at Washington University at St. Louis; and Dr. Ashis Basu, a chemist at University of Connecticut.