Carlo Croce M MD


Carlo Croce M MD
ChairCollege of Medicinecroce.5@osu.edu
1082 Biomedical Research Tower 460 W 12th Avenue Columbus Ohio 43210
Phone:614-292-3063Fax: (614) 292-4080
  • Molecular Biology and Cancer Genetics
  • Administrative

Current Publications

  • Zappasodi R, Cavanè A, Iorio MV, Tortoreto M, Guarnotta C, Ruggiero G, Piovan C, Magni M, Zaffaroni N, Tagliabue E, Croce CM, Zunino F, Gianni AM, Di Nicola MPleiotropic antitumor effects of the pan-HDAC inhibitor ITF2357 against c-Myc-overexpressing human B-cell non-Hodgkin lymphomas.Int J Cancer 135 2034-45 11/1/2014
  • Ryan BM, Wolff RK, Valeri N, Khan M, Robinson D, Paone A, Bowman ED, Lundgreen A, Caan B, Potter J, Brown D, Croce C, Slattery ML, Harris CCAn analysis of genetic factors related to risk of inflammatory bowel disease and colon cancer.Cancer Epidemiol in press 8/14/2014
  • Sapienza MR, Fuligni F, Agostinelli C, Tripodo C, Righi S, Laginestra MA, Pileri A Jr, Mancini M, Rossi M, Ricci F, Gazzola A, Melle F, Mannu C, Ulbar F, Arpinati M, Paulli M, Maeda T, Gibellini D, Pagano L, Pimpinelli N, Santucci M, Cerroni L, Croce CM, Facchetti F, Piccaluga PP, Pileri SAMolecular profiling of blastic plasmacytoid dendritic cell neoplasm reveals a unique pattern and suggests selective sensitivity to NF-kB pathway inhibition.Leukemia 28 1606-16 8/1/2014
  • Croce CM, Kipps TJ, Cui B, Chen L, Zhang S, Mraz M, Fecteau JF, Yu J, Ghia EM, Zhang L, Bao L, Rassenti LZ, Messer K, Calin GAMicroRNA-155 influences B-cell receptor signaling and associates with aggressive disease in chronic lymphocytic leukemia.Blood 124 546-54 7/24/2014
  • Acunzo M, Romano G, Wernicke D, Balatti V, Rassenti LZ, dell'Aquila M, Kipps TJ, Pekarsky Y, Croce CMTranslocation t(2;11) in CLL cells results in CXCR4/MAML2 fusion oncogene.Blood 124 259-62 7/10/2014
  • Deckert J, Croce CM, Flynn JM, Andritsos LA, Jones JA, Maddocks KJ, Lozanski G, Byrd JC, Muthusamy N, Beckwith KA, Frissora FW, Stefanovski MR, Towns WH, Cheney C, Mo XThe CD37-targeted antibody-drug conjugate IMGN529 is highly active against human CLL and in a novel CD37 transgenic murine leukemia model.Leukemia 28 1501-10 7/1/2014
  • Pekarsky Y, Croce CMRole of miR-15/16 in CLL.Cell Death Differ in press 6/27/2014
  • Werner L, Croce CM, Riches JC, O'Donovan CJ, Kingdon SJ, McClanahan F, Clear AJ, Neuberg DS, Ramsay AG, Rassenti LZ, Kipps TJ, Gribben JGTrisomy 12 chronic lymphocytic leukemia cells exhibit upregulation of integrin signaling that is modulated by NOTCH1 mutations.Blood 123 4101-10 6/26/2014
  • Mandeville M, Martin-Buley LA, Croce CM, Lian JB, van Wijnen AJ, Stein JL, Altieri DC, Stein GS, Kapinas K, Kim HmicroRNA-Mediated Survivin Control of Pluripotency.J Cell Physiol in press 6/2/2014
  • Martens-Uzunova ES, Böttcher R, Croce CM, Jenster G, Visakorpi T, Calin GALong noncoding RNA in prostate, bladder, and kidney cancer.Eur Urol 65 1140-51 6/1/2014
  • Wei H, Wang C, Croce CM, Guan JLp62/SQSTM1 synergizes with autophagy for tumor growth in vivo.Genes Dev 28 1204-16 6/1/2014
  • Pero R, Valentino T, Federico A, Franco R, Lembo F, Klein-Szanto AJ, Del Vecchio L, Montanaro D, Keller S, Arra C, Papadopoulou V, Wagner SD, Croce CM, Fusco A, Chiariotti L, Fedele M, Palmieri D, Angrisano TPOZ-, AT-hook-, and zinc finger-containing protein (PATZ) interacts with human oncogene B cell lymphoma 6 (BCL6) and is required for its negative autoregulation.J Biol Chem 289 14966 5/23/2014
  • Veronese A, Pepe F, Chiacchia J, Pagotto S, Lanuti P, Veschi S, Di Marco M, D'Argenio A, Innocenti I, Vannata B, Autore F, Marchisio M, Wernicke D, Verginelli F, Leone G, Rassenti LZ, Kipps TJ, Mariani-Costantini R, Laurenti L, Croce CM, Visone RAllele-specific loss and transcription of the miR-15a/16-1 cluster in chronic lymphocytic leukemia.Leukemia in press 4/15/2014
  • Valeri N, Braconi C, Gasparini P, Murgia C, Lampis A, Paulus-Hock V, Hart JR, Ueno L, Grivennikov SI, Lovat F, Paone A, Cascione L, Sumani KM, Veronese A, Fabbri M, Carasi S, Alder H, Groden J, Vogt PK, Karin M, Sansom OJ, Croce CM, Lanza G, Gafa' R, Moyer MP, Ridgway RA, Cordero J, Nuovo GJ, Frankel WL, Rugge M, Fassan MMicroRNA-135b promotes cancer progression by acting as a downstream effector of oncogenic pathways in colon cancer.Cancer Cell 25 469-83 4/14/2014
  • Havelange V, Ranganathan P, Geyer S, Nicolet D, Huang X, Yu X, Volinia S, Kornblau SM, Andreeff M, Croce CM, Marcucci G, Bloomfield CD, Garzon RImplications of the miR-10 family in chemotherapy response of NPM1-mutated AML.Blood 123 2412-5 4/10/2014
  • Zhang M, Luo Z, Liu H, Croce CM, Burke TR Jr, Bottaro DPSynergistic anti-leukemic activity of imatinib in combination with a small molecule Grb2 SH2 domain binding antagonist.Leukemia 28 948-51 4/1/2014
  • He WA, Calore F, Londhe P, Canella A, Guttridge DC, Croce CMMicrovesicles containing miRNAs promote muscle cell death in cancer cachexia via TLR7.Proc Natl Acad Sci U S A 111 4525-9 3/25/2014
  • Gasparini P, Lovat F, Fassan M, Casadei L, Cascione L, Jacob NK, Carasi S, Palmieri D, Costinean S, Shapiro CL, Huebner K, Croce CMProtective role of miR-155 in breast cancer through RAD51 targeting impairs homologous recombination after irradiation.Proc Natl Acad Sci U S A 111 4536-41 3/25/2014
  • Saulep-Easton D, Vincent FB, Le Page M, Wei A, Ting SB, Croce CM, Tam C, Mackay FCytokine-driven loss of plasmacytoid dendritic cell function in chronic lymphocytic leukemia.Leukemia in press 3/18/2014
  • Kim T, Cui R, Jeon YJ, Lee JH, Lee JH, Sim H, Park JK, Fadda P, Tili E, Nakanishi H, Huh MI, Kim SH, Cho JH, Sung BH, Peng Y, Lee TJ, Luo Z, Sun HL, Wei H, Alder H, Oh JS, Shim KS, Ko SB, Croce CMLong-range interaction and correlation between MYC enhancer and oncogenic long noncoding RNA CARLo-5.Proc Natl Acad Sci U S A 111 4173-8 3/18/2014
  • Gasparini P, Cascione L, Fassan M, Lovat F, Guler G, Balci S, Irkkan C, Morrison C, Croce CM, Shapiro CL, Huebner KmicroRNA expression profiling identifies a four microRNA signature as a novel diagnostic and prognostic biomarker in triple negative breast cancers.Oncotarget 5 1174-84 3/15/2014
  • Armenia J, Fabris L, Lovat F, Berton S, Segatto I, D'Andrea S, Ivan C, Cascione L, Calin GA, Croce CM, Colombatti A, Vecchione A, Belletti B, Baldassarre GContact inhibition modulates intracellular levels of miR-223 in a p27kip1-dependent manner.Oncotarget 5 1185-97 3/15/2014
  • Gomez GG, Volinia S, Croce CM, Zanca C, Li M, Emnett R, Gutmann DH, Brennan CW, Furnari FB, Cavenee WKSuppression of microRNA-9 by mutant EGFR signaling upregulates FOXP1 to enhance glioblastoma tumorigenicity.Cancer Res 74 1429-39 3/1/2014
  • Lovat F, Ishii H, Schiappacassi M, Fassan M, Barbareschi M, Galligioni E, Gasparini P, Baldassarre G, Croce CM, Vecchione ALZTS1 downregulation confers paclitaxel resistance and is associated with worse prognosis in breast cancer.Oncotarget 5 970-7 2/28/2014
  • Nakanishi H, Taccioli C, Palatini J, Fernandez-Cymering C, Cui R, Kim T, Volinia S, Croce CMLoss of miR-125b-1 contributes to head and neck cancer development by dysregulating TACSTD2 and MAPK pathway.Oncogene 33 702-12 2/6/2014
  • Garofalo M, Leva GD, Croce CMMicroRNAs as Anti-Cancer Therapy.Curr Pharm Des in press 1/28/2014
  • Buchsbaum DJ, Croce CMWill detection of microRNA biomarkers in blood improve the diagnosis and survival of patients with pancreatic cancer?JAMA 311 363-5 1/22/2014
  • Widhopf GF 2nd, Cui B, Ghia EM, Chen L, Messer K, Shen Z, Briggs SP, Croce CM, Kipps TJROR1 can interact with TCL1 and enhance leukemogenesis in Eμ-TCL1 transgenic mice.Proc Natl Acad Sci U S A 111 793-8 1/14/2014
  • Di Leva G, Garofalo M, Croce CMMicroRNAs in cancer.Annu Rev Pathol 9 287-314 1/1/2014
  • Olivo-Marston SE, Hursting SD, Perkins SN, Schetter A, Khan M, Croce C, Harris CC, Lavigne JEffects of calorie restriction and diet-induced obesity on murine colon carcinogenesis, growth and inflammatory factors, and microRNA expression.PLoS One 9 e94765 1/1/2014
  • Collins AL, Wojcik S, Liu J, Frankel WL, Alder H, Yu L, Schmittgen TD, Croce CM, Bloomston MA differential microRNA profile distinguishes cholangiocarcinoma from pancreatic adenocarcinoma.Ann Surg Oncol 21 133-8 1/1/2014
  • Efanov A, Zanesi N, Coppola V, Nuovo G, Bolon B, Wernicle-Jameson D, Lagana A, Hansjuerg A, Pichiorri F, Croce CMHuman HMGA2 protein overexpressed in mice induces precursor T-cell lymphoblastic leukemia.Blood Cancer J 4 e227 1/1/2014
  • Laganà A, Acunzo M, Romano G, Pulvirenti A, Veneziano D, Cascione L, Giugno R, Gasparini P, Shasha D, Ferro A, Croce CMmiR-Synth: a computational resource for the design of multi-site multi-target synthetic miRNAs.Nucleic Acids Res 42 5416-25 1/1/2014
  • Gasparini P, Fassan M, Lovat F, Morrison C, Zhang J, Scarpa A, Croce CM, Shapiro CL, Huebner K, Cascione L, Guler G, Balci S, Irkkan C, Paisie CAndrogen receptor status is a prognostic marker in non-basal triple negative breast cancers and determines novel therapeutic options.PLoS One 9 e88525 1/1/2014
  • Ciardi A, Croce CM, Drusco A, Nuovo GJ, Zanesi N, Di Leva G, Pichiorri F, Volinia S, Fernandez C, Antenucci A, Costinean S, Bottoni A, Rosito IA, Liu CG, Burch A, Acunzo M, Pekarsky Y, Alder HMicroRNA Profiles Discriminate among Colon Cancer Metastasis.PLoS One 9 e96670 1/1/2014
  • Volinia S, Muti P, Strano S, Croce CM, Pass HI, Blandino G, Cioce M, Ganci F, Canu V, Sacconi A, Mori F, Canino C, Korita E, Casini B, Alessandrini G, Cambria A, Carosi MA, Blandino R, Panebianco V, Facciolo F, Visca PProtumorigenic effects of mir-145 loss in malignant pleural mesothelioma.Oncogene in press 11/18/2013
  • Sandhu SK, Fassan M, Volinia S, Lovat F, Balatti V, Pekarsky Y, Croce CMB-cell malignancies in microRNA Eμ-miR-17~92 transgenic mice.Proc Natl Acad Sci U S A 110 18208-13 11/5/2013
  • Mace TA, Collins AL, Wojcik SE, Croce CM, Lesinski GB, Bloomston MHypoxia induces the overexpression of microRNA-21 in pancreatic cancer cells.J Surg Res 184 855-60 10/1/2013
  • Meng W, Ye Z, Cui R, Perry J, Dedousi-Huebner V, Huebner A, Wang Y, Li B, Volinia S, Nakanishi H, Kim T, Suh SS, Ayers LW, Ross P, Croce CM, Chakravarti A, Jin VX, Lautenschlaeger TMicroRNA-31 predicts the presence of lymph node metastases and survival in patients with lung adenocarcinoma.Clin Cancer Res 19 5423-33 10/1/2013
  • Neviani P, Harb JG, Oaks JJ, Santhanam R, Walker CJ, Ellis JJ, Ferenchak G, Dorrance AM, Paisie CA, Eiring AM, Ma Y, Mao HC, Zhang B, Wunderlich M, May PC, Sun C, Hokland P, Roy DC, Milojkovic D, Apperley J, Goldman JM, Reid A, Saddoughi SA, Bielawski J, Blum W, Klisovic RB, Solt JA, Byrd JC, Volinia S, Cortes J, Huettner CS, Koschmieder S, Holyoake TL, Devine S, Caligiuri MA, Croce CM, Garzon R, Ogretmen B, Arlinghaus RB, Chen CS, Bittman R, Mulloy JC, Bhatia R, Marcucci G, Perrotti DPP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells.J Clin Invest 123 4144-57 10/1/2013
  • Sun HL, Cui R, Wei H, Kim T, Lee TJ, Jeon YJ, Nuovo GJ, Volinia S, He Q, Yu J, Nana-Sinkam P, Croce CM, Peng Y, Dai Y, Hitchcock C, Yang X, Kassis ES, Liu L, Luo ZInsulin growth factor signaling is regulated by microRNA-486, an underexpressed microRNA in lung cancer.Proc Natl Acad Sci U S A 110 15043-8 9/10/2013
  • Hudson RS, Yi M, Esposito D, Glynn SA, Starks AM, Yang Y, Schetter AJ, Watkins SK, Hurwitz AA, Dorsey TH, Stephens RM, Croce CM, Ambs SMicroRNA-106b-25 cluster expression is associated with early disease recurrence and targets caspase-7 and focal adhesion in human prostate cancer.Oncogene 32 4139-47 8/29/2013
  • Balkhi MY, Balkhi MY, Iwenofu OH, Kraybill W, Perrotti D, Croce CM, Keller C, Guttridge DC, Bakkar N, Ladner KJ, Chandler DS, Houghton PJ, London CAmiR-29 acts as a decoy in sarcomas to protect the tumor suppressor A20 mRNA from degradation by HuR.Sci Signal 6 ra63 7/30/2013
  • Ortuso F, Paduano F, Carotenuto A, Gomez-Monterrey I, Bilotta A, Gaudio E, Sala M, Artese A, Vernieri E, Dattilo V, Iuliano R, Brancaccio D, Bertamino A, Musella S, Alcaro S, Grieco P, Perrotti N, Croce CM, Novellino E, Fusco A, Campiglia P, Trapasso FDiscovery of PTPRJ agonist peptides that effectively inhibit in vitro cancer cell proliferation and tube formation.ACS Chem Biol 8 1497-506 7/19/2013
  • Di Leva G, Croce CMMicroRNAs.Clin Biochem 46 840-1 7/1/2013
  • Garofalo M, Croce CMMicroRNAs as therapeutic targets in chemoresistance.Drug Resist Updat 16 47-59 7/1/2013
  • Galli R, Paone A, Fabbri M, Zanesi N, Calore F, Cascione L, Acunzo M, Stoppacciaro A, Tubaro A, Lovat F, Gasparini P, Fadda P, Alder H, Volinia S, Filippini A, Ziparo E, Riccioli A, Croce CMToll-like receptor 3 (TLR3) activation induces microRNA-dependent reexpression of functional RARβ and tumor regression.Proc Natl Acad Sci U S A 110 9812-7 6/11/2013
  • Cirombella R, Onesti EC, Pellegrini P, Califano D, Pignata S, Losito S, Canzonieri V, Sorio R, Alder H, Wernicke D, Stoppacciaro A, Baldassarre G, Croce CM, Vecchione A, Belletti B, Lovat F, Volinia S, Chiappetta G, Giglio S, Sonego MA microRNA signature defines chemoresistance in ovarian cancer through modulation of angiogenesis.Proc Natl Acad Sci U S A 110 9845-50 6/11/2013
  • Croce CMMicroRNA dysregulation in acute myeloid leukemia.J Clin Oncol 31 2065-6 6/10/2013
  • Chen Y, Jacamo R, Konopleva M, Garzon R, Croce C, Andreeff MCXCR4 downregulation of let-7a drives chemoresistance in acute myeloid leukemia.J Clin Invest 123 2395-407 6/3/2013
  • Mussnich P, D'Angelo D, Leone V, Croce CM, Fusco AThe High Mobility Group A proteins contribute to thyroid cell transformation by regulating miR-603 and miR-10b expression.Mol Oncol 7 531-42 6/1/2013
  • Croce CM, Pekarsky Y, Zanesi N, Balatti V, Riordan J, Burch A, Rizzotto L, Palamarchuk A, Cascione L, Lagana A, Dupuy AJA Sleeping Beauty screen reveals NF-kB activation in CLL mouse model.Blood 121 4355-8 5/23/2013
  • Acunzo M, Romano G, Palmieri D, Laganá A, Garofalo M, Balatti V, Drusco A, Chiariello M, Nana-Sinkam P, Croce CMCross-talk between MET and EGFR in non-small cell lung cancer involves miR-27a and Sprouty2.Proc Natl Acad Sci U S A 110 8573-8 5/21/2013
  • Talabere T, Piovan C, Lagana A, Cascione L, Guan J, Gasparini P, Balatti V, Nuovo G, Coppola V, Hofmeister CC, Marcucci G, Byrd JC, Volinia S, Shapiro CL, Freitas MA, Croce CM, Pichiorri F, Palmieri D, De Luca L, Consiglio J, You J, Rocci AIn vivo NCL targeting affects breast cancer aggressiveness through miRNA regulation.J Exp Med 210 951-68 5/6/2013
  • Tili E, Michaille JJ, Croce CMMicroRNAs play a central role in molecular dysfunctions linking inflammation with cancer.Immunol Rev 253 167-84 5/1/2013
  • Volinia S, Croce CMPrognostic microRNA/mRNA signature from the integrated analysis of patients with invasive breast cancer.Proc Natl Acad Sci U S A 110 7413-7 4/30/2013
  • Croce CM, Caligiuri MA, Trotta R, Chen L, Costinean S, Josyula S, Mundy-Bosse BL, Ciarlariello D, Mao C, Briercheck EL, McConnell KK, Mishra A, Yu LOverexpression of miR-155 causes expansion, arrest in terminal differentiation and functional activation of mouse natural killer cells.Blood 121 3126-34 4/18/2013
  • Di Leva G, Piovan C, Gasparini P, Ngankeu A, Taccioli C, Briskin D, Cheung DG, Bolon B, Anderlucci L, Alder H, Nuovo G, Li M, Iorio MV, Galasso M, Ramasamy S, Marcucci G, Perrotti D, Powell KA, Bratasz A, Garofalo M, Nephew KP, Croce CMCorrection: Estrogen Mediated-Activation of miR-191/425 Cluster Modulates Tumorigenicity of Breast Cancer Cells Depending on Estrogen Receptor Status.PLoS Genet 9(4) 4/1/2013
  • Balatti V, Lerner S, Rizzotto L, Rassenti LZ, Bottoni A, Palamarchuk A, Cascione L, Alder H, Keating MJ, Kipps TJ, Pekarsky Y, Croce CMTrisomy 12 CLLs progress through NOTCH1 mutations.Leukemia 27 740-3 3/1/2013
  • Di Leva G, Croce CMmiRNA profiling of cancer.Curr Opin Genet Dev 23 3-11 2/1/2013
  • Tsongalis GJ, Calin G, Cordelier P, Croce C, Monzon F, Szafranska-Schwarzbach AEMicroRNA analysis: is it ready for prime time?Clin Chem 59 343-7 2/1/2013
  • Fabbri M, Paone A, Calore F, Galli R, Croce CMA new role for microRNAs, as ligands of Toll-like receptors.RNA Biol 10 169-74 2/1/2013
  • Gaudio E, Paduano F, Ngankeu A, Lovat F, Fabbri M, Sun HL, Gasparini P, Efanov A, Peng Y, Zanesi N, Shuaib MA, Rassenti LZ, Kipps TJ, Li C, Aqeilan RI, Lesinski GB, Trapasso F, Croce CMHeat shock protein 70 regulates Tcl1 expression in leukemia and lymphomas.Blood 121 351-9 1/10/2013
  • Di Leva G, Croce CMThe Role of microRNAs in the Tumorigenesis of Ovarian Cancer.Front Oncol 3 153 1/1/2013
  • Nana-Sinkam SP, Croce CMClinical applications for microRNAs in cancer.Clin Pharmacol Ther 93 98-104 1/1/2013
  • Iorio MV, Croce CMMicroRNA profiling in ovarian cancer.Methods Mol Biol 1049 187-97 1/1/2013
  • Balatti V, Pekarky Y, Rizzotto L, Croce CMmiR deregulation in CLL.Adv Exp Med Biol 792 309-25 1/1/2013
  • Ouzounova M, Vuong T, Ancey PB, Ferrand M, Durand G, Le-Calvez Kelm F, Croce C, Matar C, Herceg Z, Hernandez-Vargas HMicroRNA miR-30 family regulates non-attachment growth of breast cancer cells.BMC Genomics 14 139 1/1/2013
  • Laganà A, Russo F, Veneziano D, Bella SD, Giugno R, Pulvirenti A, Croce CM, Ferro AExtracellular circulating viral microRNAs: current knowledge and perspectives.Front Genet 4 120 1/1/2013
  • Cascione L, Gasparini P, Lovat F, Carasi S, Pulvirenti A, Ferro A, Alder H, He G, Vecchione A, Croce CM, Shapiro CL, Huebner KIntegrated microRNA and mRNA signatures associated with survival in triple negative breast cancer.PLoS One 8 e55910 1/1/2013
  • Fassan M, Volinia S, Palatini J, Pizzi M, Fernandez-Cymering C, Balistreri M, Realdon S, Battaglia G, Souza R, Odze RD, Zaninotto G, Croce CM, Rugge Md Facg MMicroRNA Expression Profiling in the Histological Subtypes of Barrett's Metaplasia.Clin Transl Gastroenterol 4 e34 1/1/2013
  • Hudson RS, Yi M, Volfovsky N, Prueitt RL, Esposito D, Volinia S, Liu CG, Schetter AJ, Van Roosbroeck K, Stephens RM, Calin GA, Croce CM, Ambs STranscription signatures encoded by ultraconserved genomic regions in human prostate cancer.Mol Cancer 12 13 1/1/2013
  • Romano G, Crawford M, Nana-Sinkam P, Croce CM, Garofalo M, Jeon YJ, Nuovo GJ, Middleton J, Secchiero P, Joshi P, Alder H, Nazaryan N, Di Leva GMiR-34a/c-Dependent PDGFR-α/β Downregulation Inhibits Tumorigenesis and Enhances TRAIL-Induced Apoptosis in Lung Cancer.PLoS One 8 e67581 1/1/2013
  • Aqeilan RI, Alcaro S, Croce CM, Trapasso F, Gaudio E, Paduano F, Spizzo R, Ngankeu A, Zanesi N, Gaspari M, Ortuso F, Lovat F, Rock J, Hill GA, Kaou M, Cuda GFhit delocalizes annexin a4 from plasma membrane to cytosol and sensitizes lung cancer cells to paclitaxel.PLoS One 8 e78610 1/1/2013
  • Lehman A, Ruppert AS, Bolon B, Andritsos L, Lozanski A, Rassenti L, Zhao W, Jarvinen TM, Senter L, Croce CM, Symer DE, de la Chapelle A, Heerema NA, Byrd JC, Hertlein E, Beckwith KA, Lozanski G, Chen TL, Towns WH, Johnson AJCharacterization of a new chronic lymphocytic leukemia cell line for mechanistic in vitro and in vivo studies relevant to disease.PLoS One 8 e76607 1/1/2013
  • Taccioli C, Briskin D, Cheung DG, Bolon B, Anderlucci L, Alder H, Nuovo G, Li M, Iorio MV, Galasso M, Santhanam R, Ramasamy S, Marcucci G, Perrotti D, Powell KA, Bratasz A, Garofalo M, Nephew KP, Croce CM, Di Leva G, Piovan C, Gasparini P, Ngankeu AEstrogen mediated-activation of miR-191/425 cluster modulates tumorigenicity of breast cancer cells depending on estrogen receptor status.PLoS Genet 9 e1003311 1/1/2013
  • Hassan MQ, Maeda Y, Taipaleenmaki H, Zhang W, Jafferji M, Gordon JA, Li Z, Croce CM, van Wijnen AJ, Stein JL, Stein GS, Lian JBmiR-218 directs a Wnt signaling circuit to promote differentiation of osteoblasts and osteomimicry of metastatic cancer cells.J Biol Chem 287 42084-92 12/7/2012
  • Costinean S, Galasso M, Neinast R, Santhanam R, Parthun MR, Perrotti D, Marcucci G, Garzon R, Croce CM, Sandhu SK, Volinia SmiR-155 targets histone deacetylase 4 (HDAC4) and impairs transcriptional activity of B-cell lymphoma 6 (BCL6) in the Eμ-miR-155 transgenic mouse model.Proc Natl Acad Sci U S A 109 20047-52 12/4/2012
  • Costinean S, Balatti V, Bottoni A, Old M, Croce C, Wakely PE JrPrimary intrathyroidal paraganglioma: histopathology and novel molecular alterations.Hum Pathol 43 2371-5 12/1/2012
  • Laganà A, Paone A, Veneziano D, Cascione L, Gasparini P, Carasi S, Russo F, Nigita G, Macca V, Giugno R, Pulvirenti A, Shasha D, Ferro A, Croce CMmiR-EdiTar: a database of predicted A-to-I edited miRNA target sites.Bioinformatics 28 3166-8 12/1/2012
  • Kogure T, Costinean S, Yan I, Braconi C, Croce C, Patel THepatic miR-29ab1 expression modulates chronic hepatic injury.J Cell Mol Med 16 2647-54 11/1/2012
  • Colamaio M, Calì G, Sarnataro D, Borbone E, Pallante P, Decaussin-Petrucci M, Nitsch L, Croce CM, Battista S, Fusco ALet-7a down-regulation plays a role in thyroid neoplasias of follicular histotype affecting cell adhesion and migration through its ability to target the FXYD5 (Dysadherin) gene.J Clin Endocrinol Metab 97 E2168-78 11/1/2012
  • Ortuso F, Campiglia P, Raso C, Iaccino E, Gaspari M, Gaudio E, Mangone G, Carotenuto A, Bilotta A, Narciso D, Trapasso F, Paduano F, Palmieri C, Agosti V, Artese A, Gomez-Monterrey I, Sala M, Cuda G, Iuliano R, Perrotti N, Scala G, Viglietto G, Alcaro S, Croce CM, Novellino E, Fusco AIsolation and functional characterization of peptide agonists of PTPRJ, a tyrosine phosphatase receptor endowed with tumor suppressor activity.ACS Chem Biol 7 1666-76 10/19/2012
  • Taccioli C, Chen H, Jiang Y, Liu XP, Huang K, Smalley KJ, Farber JL, Croce CM, Fong LYDietary zinc deficiency fuels esophageal cancer development by inducing a distinct inflammatory signature.Oncogene 31 4550-8 10/18/2012
  • Romano G, Acunzo M, Garofalo M, Di Leva G, Cascione L, Zanca C, Bolon B, Condorelli G, Croce CMMiR-494 is regulated by ERK1/2 and modulates TRAIL-induced apoptosis in non-small-cell lung cancer through BIM down-regulation.Proc Natl Acad Sci U S A 109 16570-5 10/9/2012
  • Tili E, Michaille JJ, Luo Z, Volinia S, Rassenti LZ, Kipps TJ, Croce CMThe down-regulation of miR-125b in chronic lymphocytic leukemias leads to metabolic adaptation of cells to a transformed state.Blood 120 2631-8 9/27/2012
  • Leone V, D'Angelo D, Pallante P, Croce CM, Fusco AThyrotropin regulates thyroid cell proliferation by up-regulating miR-23b and miR-29b that target SMAD3.J Clin Endocrinol Metab 97 3292-301 9/1/2012
  • Chen H, Jiang Y, Smalley KJ, Fadda P, Ozer HG, Huebner K, Farber JL, Croce CM, Fong LY, Alder H, Taccioli CDysregulation of miR-31 and miR-21 induced by zinc deficiency promotes esophageal cancer.Carcinogenesis 33 1736-44 9/1/2012
  • D'Abundo L, Ferracin M, Callegari E, Elamin BK, Giannone F, Milazzo M, Altavilla G, Fornari F, Giacomelli L, Bassi C, Zagatti B, Corrà F, Miotto E, Lupini L, Bolondi L, Gramantieri L, Croce CM, Sabbioni S, Negrini MLiver tumorigenicity promoted by microRNA-221 in a mouse transgenic model.Hepatology 56 1025-33 9/1/2012
  • Ranganathan P, Yu X, Na C, Santhanam R, Shacham S, Kauffman M, Walker A, Klisovic R, Blum W, Caligiuri M, Croce CM, Marcucci G, Garzon RPreclinical activity of a novel CRM1 inhibitor in acute myeloid leukemia.Blood 120 1765-73 8/30/2012

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