Sung OK Yoon PhD


Sung OK Yoon PhD
Assoc ProfessorCollege of Medicineyoon.84@osu.edu
184 Rightmire Hall 1060 Carmack Road Columbus Ohio 43210
Phone:614-292-8542Fax: 614-292-5379
  • Molecular Biology and Cancer Genetics

General Research Interest

JNK signaling, polarity in glioma invasion, Alzheimer's disease

Research Description

The long-term goal of the lab is to understand how the balance between cell survival and death is maintained in the adult nervous system.  Currently, we are focusing on the role of stress kinase, JNK signaling, under pathological conditions.

Transinstitutional Work

In collaboration with Drs. M. Viapiano and C.H. Kwon, we are investigating the role of small GTPase and polarity proteins in glioma invasion. 

Current Publications

  • Yoon SOChanges in Spontaneous firing patterns of cerebellar Purkinje cells in p75 knockout mice.Cerebellum 12(3) 6/1/2013
  • Lu QRNF-κB forms a complex with the chromatin remodeler BRG1 to regulate Schwann cell differentiation.J Neurosci 33(6) 2/6/2013
  • Yoon SOOral administration of a small molecule targeted to block proNGF binding to p75 promotes myelin sparing and functional recovery after spinal cord injury.J Neurosci 33(2) 1/9/2013
  • Huang KJNK3 perpetuates metabolic stress induced by Aβ peptides.Neuron 75(5) 9/6/2012

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 300 W. 10th Ave. Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu