Matthew During MD, PhD


Matthew During MD, PhD
ProfessorCollege of Medicineduring.1@osu.edu
912 Biomedical Research Tower 460 W 12th Avenue Columbus Ohio 43210
Phone:Fax: (614) 688-0731
  • Molecular Biology and Cancer Genetics

Current Publications

  • Carruthers KH, Metzger G, During MJ, Muravlev A, Wang C, Kocak EGene-directed enzyme prodrug therapy for localized chemotherapeutics in allograft and xenograft tumor models.Cancer Gene Ther 21 434-40 10/1/2014
  • Young D, Fong DM, Lawlor PA, Wu A, Mouravlev A, McRae M, Glass M, Dragunow M, During MJAdenosine kinase, glutamine synthetase and EAAT2 as gene therapy targets for temporal lobe epilepsy.Gene Ther in press 9/18/2014
  • Iyirhiaro GO, Zhang Y, Estey C, O'Hare MJ, Safarpour F, Parsanejad M, Wang S, Abdel-Messih E, Callaghan SM, During MJ, Slack RS, Park DSRegulation of Ischemic Neuronal Death by E2F4-p130 Protein Complexes.J Biol Chem 289 18202-13 6/27/2014
  • Kalev-Zylinska ML, Green TN, Morel-Kopp MC, Sun PP, Park YE, Lasham A, During MJ, Ward CMN-methyl-D-aspartate receptors amplify activation and aggregation of human platelets.Thromb Res 133 837-47 5/1/2014
  • O'Neill B, Tilley MR, Han DD, Thirtamara-Rajamani K, Hill ER, Bishop GA, Zhou FM, During MJ, Gu HHBehavior of knock-in mice with a cocaine-insensitive dopamine transporter after virogenetic restoration of cocaine sensitivity in the striatum.Neuropharmacology 79 626-33 4/1/2014
  • Liu X, Magee D, Wang C, McMurphy T, Slater A, During M, Cao LAdipose tissue insulin receptor knockdown via a new primate-derived hybrid recombinant AAV serotype.Mol Ther Methods Clin Dev 1 2/5/2014
  • D'mello SA, Flanagan JU, Green TN, Leung EY, Askarian-Amiri ME, Joseph WR, McCrystal MR, Isaacs RJ, Shaw JH, Furneaux CE, During MJ, Finlay GJ, Baguley BC, Kalev-Zylinska MLEvidence That GRIN2A Mutations in Melanoma Correlate with Decreased Survival.Front Oncol 3 333 1/13/2014
  • Tsang VW, Young D, During MJ, Birch NPAAV-mediated overexpression of neuroserpin in the hippocampus decreases PSD-95 expression but does not affect hippocampal-dependent learning and memory.PLoS One 9 e91050 1/1/2014
  • Blouin AM, Stern AL, Han S, Theberge FR, Wang C, During MJ, Baraban JM, Reti IMNeuronal activity-regulated pentraxin expressed in medial prefrontal cortex neurons is not necessary for extinction of heroin self-administration.Behav Pharmacol 24 332-6 8/1/2013
  • Kalev-Zylinska ML, Symes W, Little KC, Sun P, Wen D, Qiao L, Young D, During MJ, Barber PAStroke patients develop antibodies that react with components of N-methyl-D-aspartate receptor subunit 1 in proportion to lesion size.Stroke 44 2212-9 8/1/2013
  • Carruthers KH, During MJ, Muravlev A, Wang C, Kocak EFat grafting as a vehicle for the delivery of recombinant adenoassociated viral vectors to achieve gene modification of muscle flaps.Ann Plast Surg 70 726-31 6/1/2013
  • Blouin AM, Han S, Pearce AM, Cheng K, Lee JJ, Johnson AW, Wang C, During MJ, Holland PC, Shaham Y, Baraban JM, Reti IMRole of medial prefrontal cortex Narp in the extinction of morphine conditioned place preference.Learn Mem 20 75-9 1/1/2013
  • Charbel Issa P, De Silva SR, Singh MS, Mouravlev A, Lipinski DM, You Q, Barnard AR, Hankins MW, During MJ, Maclaren REAssessment of tropism and effectiveness of new primate-derived hybrid recombinant AAV serotypes in the mouse and primate retina.PLoS One 8 e60361 1/1/2013
  • Leone P, Shera D, McPhee SW, Francis JS, Kolodny EH, Bilaniuk LT, Wang DJ, Assadi M, Goldfarb O, Goldman HW, Freese A, Young D, During MJ, Samulski RJ, Janson CGLong-term follow-up after gene therapy for canavan disease.Sci Transl Med 4 165ra163 12/19/2012

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 460 W. 10th Avenue, Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu