Ramesh Ganju K PhD

Ramesh Ganju K PhD
ProfessorCollege of Medicineganju.1@osu.edu
810 Biomedical Research Tower 460 W 12th Avenue Columbus Ohio 43210
Phone:614-292-5539Fax: (614) 247-0051
  • Molecular Biology and Cancer Genetics

Research Description

The major focus of Dr. Ganju's lab is to determine the role of chemokines, especially CXCL12, and various inflammatory molecules, such as S100A7, and anti-inflammatory molecules, such as Slit2 and cannabinoids, in pathogenesis of various diseases.

Current Publications

  • Oghumu S, Varikuti S, Terrazas C, Kotov D, Nasser MW, Powell CA, Ganju RK, Satoskar ARCXCR3 deficiency enhances tumor progression by promoting macrophage M2 polarization in a murine breast cancer model.Immunology 143 109-19 9/1/2014
  • Chakravarti B, Ravi J, Ganju RKCannabinoids as therapeutic agents in cancer: current status and future implications.Oncotarget 5 5852-72 8/30/2014
  • Ravi J, Sneh A, Shilo K, Nasser MW, Ganju RKFAAH inhibition enhances anandamide mediated anti-tumorigenic effects in non-small cell lung cancer by downregulating the EGF/EGFR pathway.Oncotarget 5 2475-86 5/15/2014
  • Wang B, Hsu SH, Wang X, Kutay H, Bid HK, Yu J, Ganju RK, Jacob ST, Yuneva M, Ghoshal KReciprocal regulation of microRNA-122 and c-Myc in hepatocellular cancer: role of E2F1 and transcription factor dimerization partner 2.Hepatology 59 555-66 2/1/2014
  • Zhao H, Anand AR, Ganju RKSlit2-Robo4 pathway modulates lipopolysaccharide-induced endothelial inflammation and its expression is dysregulated during endotoxemia.J Immunol 192 385-93 1/1/2014
  • Wani N, Nasser MW, Ahirwar DK, Zhao H, Miao Z, Shilo K, Ganju RKC-X-C motif chemokine 12/C-X-C chemokine receptor type 7 signaling regulates breast cancer growth and metastasis by modulating the tumor microenvironment.Breast Cancer Res 16 R54 1/1/2014
  • Sneh A, Deol YS, Ganju A, Shilo K, Rosol TJ, Nasser MW, Ganju RKDifferential role of psoriasin (S100A7) in estrogen receptor α positive and negative breast cancer cells occur through actin remodeling.Breast Cancer Res Treat 138 727-39 4/1/2013
  • Anand AR, Zhao H, Nagaraja T, Robinson LA, Ganju RKN-terminal Slit2 inhibits HIV-1 replication by regulating the actin cytoskeleton.Retrovirology 10 2 1/1/2013

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 460 W. 10th Avenue, Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu