Jian-Qiu Wu PhD


Jian-Qiu Wu PhD
Assoc ProfessorArts and Scienceswu.620@osu.eduwebsite
615 Bioscience Building 484 W 12th Avenue Columbus Ohio 43210
Phone:614-247-6680Fax: (614) 292-4466
  • Molecular Biology and Cancer Genetics

General Research Interest

Roles of cytoskeletal and signaling proteins in cellular asymmetry and cell division in normal, cancer, and stem cells.

Research Description

The goal of Dr. Wu's laboratory is to understand the roles of cytoskeletal and signaling proteins in cellular asymmetry and cell division in normal and cancer cells. We are focusing on the molecular mechanisms of cytokinesis in the fission yeast S. pombe. Cytokinesis partitions cellular constituents into two daughter cells at the end of the cell cycle. When coordinated with the generation of cellular asymmetry, cytokinesis can produce diverse cell types in multicellular organisms. Thus, cytokinesis plays a crucial role in both cell proliferation and cell differentiation.

Current Publications

  • Wang N, Lo Presti L, Zhu YH, Kang M, Wu Z, Martin SG, Wu JQThe novel proteins Rng8 and Rng9 regulate the myosin-V Myo51 during fission yeast cytokinesis.J Cell Biol 205 357-75 5/12/2014
  • Coffman VC, Wu JQEvery laboratory with a fluorescence microscope should consider counting molecules.Mol Biol Cell 25 1545-8 5/1/2014
  • Zhu YH, Wu JQCell-size control: complicated.Cell Cycle 13 693-4 3/1/2014
  • Coffman VC, Sees JA, Kovar DR, Wu JQThe formins Cdc12 and For3 cooperate during contractile ring assembly in cytokinesis.J Cell Biol 203 101-14 10/14/2013
  • Zhu YH, Ye Y, Wu Z, Wu JQCooperation between Rho-GEF Gef2 and its binding partner Nod1 in the regulation of fission yeast cytokinesis.Mol Biol Cell 24 3187-204 10/1/2013
  • Coffman VC, Wu JQCounting protein molecules using quantitative fluorescence microscopy.Trends Biochem Sci 37 499-506 11/1/2012
  • Lee IJ, Coffman VC, Wu JQContractile-ring assembly in fission yeast cytokinesis: Recent advances and new perspectives.Cytoskeleton (Hoboken) 69 751-63 10/1/2012

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 300 W. 10th Ave. Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu