Jian-Qiu Wu PhD


Jian-Qiu Wu PhD
Assoc ProfessorArts and Scienceswu.620@osu.eduwebsite
615 Bioscience Building 484 W 12th Avenue Columbus Ohio 43210
Phone:614-247-6680Fax: 614-292-4466
  • Molecular Biology and Cancer Genetics

General Research Interest

Roles of cytoskeletal and signaling proteins in cellular asymmetry and cell division in normal, cancer, and stem cells.

Research Description

The long-term goal of our laboratory is to understand the roles of cytoskeletal and signaling proteins in cellular asymmetry and cell division in normal and cancer cells. In the near term, we are focusing on the molecular mechanisms of cytokinesis in the fission yeast S. pombe. Cytokinesis partitions cellular constituents into two daughter cells at the end of the cell cycle. When coordinated with the generation of cellular asymmetry, cytokinesis can produce diverse cell types in multicellular organisms. Thus, cytokinesis plays a crucial role in both cell proliferation and cell differentiation.

Current Publications

  • Wu JQCell-size control: Complicated.Cell Cycle 13 2/4/2014
  • Wu JQThe formins Cdc12 and For3 cooperate during contractile ring assembly in cytokinesis.J Cell Biol 203 101-14 10/14/2013
  • Wu JQCooperation between Rho-GEF Gef2 and its binding partner Nod1 in the regulation of fission yeast cytokinesis.Mol Biol Cell 24(20) 10/1/2013
  • Wu JQContractile-ring assembly in fission yeast cytokinesis: Recent advances and new perspectives.Cytoskeleton (Hoboken) 69(10) 10/1/2012
  • Wu JQCharacterization of Mid1 domains for targeting and scaffolding in fission yeast cytokinesis.J Cell Sci 125(Pt 12) 6/15/2012

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 300 W. 10th Ave. Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu