Heather Hampel L MS, CGC


Heather Hampel L MS, CGC
Professor - ClinicalCollege of MedicineHeather.Hampel@osumc.edu
1000 Polaris Parkway 2001 Polaris Pkwy Columbus OH 43240
Phone:(614) 293-7240Fax:
  • Molecular Biology and Cancer Genetics

Research Description

Ms. Hampel's research interests include screening all colorectal and endometrial cancer patients for Lynch syndrome, the American Founder Mutation (exon 1-6 deletion in MSH2) as a cause of Lynch syndrome, and the etiology of MSI-negative familial colorectal cancers.

Current Publications

  • Mange S, Bellcross C, Cragun D, Duquette D, Gorman L, Hampel H, Jasperson KCreation of a Network to Promote Universal Screening for Lynch Syndrome: The Lynch Syndrome Screening Network.J Genet Couns in press 9/16/2014
  • Haraldsdottir S, Hampel H, Tomsic J, Frankel WL, Pearlman R, de la Chapelle A, Pritchard CCColon and Endometrial Cancers with Mismatch Repair Deficiency can Arise from Somatic, Rather Than Germline, Mutations.Gastroenterology in press 9/3/2014
  • Haraldsdottir S, Hampel H, Wei L, Wu C, Frankel W, Bekaii-Saab T, de la Chapelle A, Goldberg RMProstate cancer incidence in males with Lynch syndrome.Genet Med 16 553-7 7/1/2014
  • Hampel HNCCN Increases the Emphasis on Genetic/Familial High-Risk Assessment in Colorectal Cancer.J Natl Compr Canc Netw 12 829-31 5/1/2014
  • Cragun D, Debate RD, Vadaparampil ST, Baldwin J, Hampel H, Pal TComparing universal Lynch syndrome tumor-screening programs to evaluate associations between implementation strategies and patient follow-through.Genet Med in press 3/20/2014
  • Morak M, Heidenreich B, Keller G, Hampel H, Laner A, de la Chapelle A, Holinski-Feder EBiallelic MUTYH mutations can mimic Lynch syndrome.Eur J Hum Genet in press 2/12/2014
  • da Silva RE, Mitchell AJ, Frisoni GB, Bokde AL, Fellgiebel A, Filippi M, Hampel H, Klöppel S, Teipel SJ, Kilimann I, Grothe M, Heinsen H, Alho EJ, Grinberg L, Amaro E Jr, Dos Santos GASubregional basal forebrain atrophy in Alzheimer's disease: a multicenter study.J Alzheimers Dis 40 687-700 1/1/2014
  • Provenzale D, Rao MS, Shike M, Steinbach G, Terdiman JP, Weinberg D, Dwyer M, Freedman-Cass D, National comprehensive cancer network, Burt RW, Cannon JA, David DS, Early DS, Ford JM, Giardiello FM, Halverson AL, Hamilton SR, Hampel H, Ismail MK, Jasperson K, Klapman JB, Lazenby AJ, Lynch PM, Mayer RJ, Ness RMColorectal cancer screening.J Natl Compr Canc Netw 11 1538-75 12/1/2013
  • Jones KA, Kim PD, Patel BB, Kelsen SG, Braverman A, Swinton DJ, Gafken PR, Jones LA, Lane WS, Neveu JM, Leung HC, Shaffer SA, Leszyk JD, Stanley BA, Fox TE, Stanley A, Hall MJ, Hampel H, South CD, de la Chapelle A, Burt RW, Jones DA, Kopelovich L, Yeung ATImmunodepletion plasma proteomics by tripleTOF 5600 and Orbitrap elite/LTQ-Orbitrap Velos/Q exactive mass spectrometers.J Proteome Res 12 4351-65 10/4/2013
  • Jin M, Hampel H, Pilarski R, Zhou X, Peters S, Frankel WLPhosphatase and tensin homolog immunohistochemical staining and clinical criteria for Cowden syndrome in patients with trichilemmoma or associated lesions.Am J Dermatopathol 35 637-40 8/1/2013
  • Hampel H, Zhou X, Schunemann L, Yearsley M, Jin M, Frankel WLBRAF V600E mutation analysis simplifies the testing algorithm for Lynch syndrome.Am J Clin Pathol 140 177-83 8/1/2013
  • Hampel H, de la Chapelle AHow do we approach the goal of identifying everybody with Lynch syndrome?Fam Cancer 12 313-7 6/1/2013
  • Plocharczyk EF, Frankel WL, Hampel H, Peters SBMismatch repair protein deficiency is common in sebaceous neoplasms and suggests the importance of screening for Lynch syndrome.Am J Dermatopathol 35 191-5 4/1/2013
  • Soyombo AA, Wu Y, Kolski L, Rios JJ, Rakheja D, Chen A, Kehler J, Hampel H, Coughran A, Ross TSAnalysis of Induced Pluripotent Stem Cells from a BRCA1 Mutant Family.Stem Cell Reports 1 336-49 1/1/2013
  • Hampel H, Aaltonen LA, Hopper JL, Le Marchand L, Gallinger S, Newcomb PA, Haile R, Thibodeau SN, Gunawardena S, Jenkins MA, Buchanan DD, Potter JD, Baron JA, Ahnen DJ, Moreno V, Andreu M, Ponz de Leon M, Rustgi AK, Moreira L, Balaguer F, Lindor N, de la Chapelle A, Castells A, EPICOLON ConsortiumIdentification of Lynch syndrome among patients with colorectal cancer.JAMA 308 1555-65 10/17/2012

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 300 W. 10th Ave. Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu