Paul J Goodfellow PhD


Paul J Goodfellow PhD
ProfessorCollege of Medicinegoodfellow.12@osu.edu
808 Biomedical Research Tower 460 W 12th Avenue Columbus Ohio 43210
Phone:614-685-6911Fax:
  • Molecular Biology and Cancer Genetics

Research Description

Dr. Goodfellow’s research focuses on understanding the role that loss of DNA mismatch repair plays in tumor initiation and progression and understanding key molecular events that can be used to develop novel approaches to the prevention and treatment of endometrial cancers.

Current Publications

  • Suarez AAMismatch repair protein expression in 1049 endometrial carcinomas, associations with body mass index, and other clinicopathologic variables.Gynecol Oncol 133 43-7 4/1/2014
  • Uyar DSHypermethylation of miR-203 in endometrial carcinomas.Gynecol Oncol 2/14/2014
  • Zighelboim I, Mutch DG, Knapp A, Ding L, Xie M, Cohn DE, Goodfellow PJHigh frequency strand slippage mutations in CTCF in MSI-positive endometrial cancers.Hum Mutat 35 63-5 1/1/2014
  • Ding LIntegrated analysis of germline and somatic variants in ovarian cancer.Nat Commun 5 3156 1/1/2014
  • Hsu YT, Gu F, Huang YW, Liu J, Ruan J, Huang RL, Wang CM, Chen CL, Jadhav R, Lai HC, Mutch DG, Goodfellow PJ, Thompson IM Jr, Kirma NB, Huang THPromoter hypomethylation of EpCAM-regulated bone morphogenetic protein gene family in recurrent endometrial cancer.Clin Cancer Res 19 6272-85 11/15/2013
  • Creutzberg CL, Kitchener HC, Birrer MJ, Landoni F, Lu KH, Powell M, Aghajanian C, Edmondson R, Goodfellow PJ, Quinn M, Salvesen HB, Thomas GGynecologic Cancer InterGroup (GCIG) Endometrial Cancer Clinical Trials Planning Meeting: Taking Endometrial Cancer Trials Into the Translational Era.Int J Gynecol Cancer 23(8) 1528-1534 10/1/2013
  • Yin Y, Kizer NT, Thaker PH, Chiappinelli KB, Trinkaus KM, Goodfellow PJ, Ma LGlycogen synthase kinase 3β inhibition as a therapeutic approach in the treatment of endometrial cancer.Int J Mol Sci 14(8) 16617-37 8/12/2013
  • McConechy MK, Ding J, Senz J, Yang W, Melnyk N, Tone AA, Prentice LM, Wiegand KC, McAlpine JN, Shah SP, Lee CH, Goodfellow PJ, Gilks CB, Huntsman DGOvarian and endometrial endometrioid carcinomas have distinct CTNNB1 and PTEN mutation profiles.Mod Pathol in press 6/14/2013
  • Novetsky AP, Zighelboim I, Thompson DM Jr, Powell MA, Mutch DG, Goodfellow PJFrequent mutations in the RPL22 gene and its clinical and functional implications.Gynecol Oncol 128(3) 470-4 3/1/2013
  • Gu F, Doderer MS, Huang YW, Roa JC, Goodfellow PJ, Kizer EL, Huang TH, Chen YCMS: a web-based system for visualization and analysis of genome-wide methylation data of human cancers.PLoS One 8(4) e60980 1/1/2013

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 300 W. 10th Ave. Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu