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Janice K. Kiecolt-Glaser PhD

Janice K. Kiecolt-Glaser PhD
ProfessorCollege of MedicineJanice.Kiecolt-Glaser@osumc.edu
130C Behavioral Med Res Inst 460 Medical Center Drive Columbus OH 43210
Phone:614-293-3499Fax:
  • Cancer Control

General Research Interest

Behavioral influences on endocrine and immune function, diet, and health

Research Description

Dr. Janice Kiecolt-Glaser’s work addresses behavioral influences on immune and endocrine function.  Her current projects address how stress and depression enhance inflammation, and how dietary and behavioral interventions may lower inflammation. For example, two of her current randomized control trials, one with medical student subjects and another with older adults, are testing the hypothesis that omega-3 supplementation can attenuate stress-related changes in inflammation and mood.  Other current studies address questions such as how genetic and environmental influences contribute to depression and immune dysregulation in older adults, the impact of major life stressors on the progression of basal cell carcinoma, the extent to which a yoga intervention can modulate endocrine and immune responses in breast cancer survivors, and the role that proinflammatory cytokines play in combination with depression among cancer survivors who experience debilitating fatigue.

Transinstitutional Work

My research program has broad interdisciplinary collaborative ties. My primary collaborator on the immunological side is Dr. Ronald Glaser, the Director of the Institute for Behavioral Medicine Research. Our studies have important endocrine components because of the interface between the endocrine immune systems, with expertise provided by Dr. William Malarkey, Department of Medicine.  Some of our newer studies address the intersection of stress/depression, diet, and immune function, conducted in collaboration with Dr. Martha Belury, Department of Human Nutrition. Our collaborations with Dr. Charles Shapiro and Dr. Tanios Bekaii-Saab provide expertise in cancer biology related to breast and colorectal cancers. Dr. Stanley Lemeshow, the Dean of the College of Public Health, and Dr. David Murray, Director of the Division of Epidemiology in the College of Public Health, provide essential biostatistical expertise. Dr. Charles Emery in the Department of Psychology, College of Social and Behavioral Sciences, is a valued collaborator with expertise in exercise interventions. Dr. Dan Birmingham, Department of Medicine, has provided critical genetic expertise for studies with older adults. Trans--institutional collaborations include Dr. Catherine Alfano in the Office of Cancer Survivorship, National Cancer Institute. 

Current Publications

  • Jaremka LM, Fagundes CP, Peng J, Bennett JM, Glaser R, Malarkey WB, Kiecolt-Glaser JKLoneliness Promotes Inflammation During Acute Stress.Psychol Sci in press 4/29/2013
  • Fagundes CP, Glaser R, Malarkey WB, Kiecolt-Glaser JKChildhood adversity and herpesvirus latency in breast cancer survivors.Health Psychol 32(3) 337-44 3/1/2013
  • Bennett JM, Glaser R, Andridge RR, Peng J, Malarkey WB, Kiecolt-Glaser JKLong lasting effects of smoking: breast cancer survivors' inflammatory responses to acute stress differ by smoking history.Psychoneuroendocrinology 38(2) 179-87 2/1/2013
  • Hosang GM, Johnson SL, Kiecolt-Glaser J, Di Gregorio MP, Lambert DR, Bechtel MA, Hearne DW, Herron JB, Glaser RGender specific association of child abuse and adult cardiovascular disease in a sample of patients with Basal Cell Carcinoma.Child Abuse Negl in press 1/21/2013
  • Fagundes CP, Glaser M, Hwang BS, Malarkey WB, Kiecolt-Glaser JKStressful early life experiences and immune dysregulation across the lifespan.Brain Behav Immun 27(1) 8-12 1/1/2013
  • Fagundes CP, Glaser M, Kiecolt-Glaser JKStressful early life experiences and immune dysregulation across the lifespan.Brain Behav Immun 27(1) 8-12 1/1/2013
  • Jaremka LM, Fagundes CP, Glaser R, Bennett JM, Malarkey WB, Kiecolt-Glaser JKLoneliness predicts pain, depression, and fatigue: Understanding the role of immune dysregulation.Psychoneuroendocrinology in press 12/26/2012
  • Lindgren ME, Fagundes CP, Alfano CM, Povoski SP, Agnese DM, Arnold MW, Farrar WB, Yee LD, Carson WE, Schmidt CR, Kiecolt-Glaser JKBeta-blockers may reduce intrusive thoughts in newly diagnosed cancer patients.Psychooncology in press 12/17/2012
  • Kiecolt-Glaser JK, Christian LM, Andridge R, Hwang BS, Malarkey WB, Belury M, Emery CF, Glaser MAdiponectin, leptin, and yoga practice.Physiol Behav 107(5) 809-13 12/5/2012
  • Gouin JP, Glaser R, Malarkey WB, Beversdorf D, Kiecolt-Glaser JKChildhood abuse and inflammatory responses to daily stressors.Ann Behav Med 44(2) 287-92 10/1/2012
  • Kiecolt-Glaser JK, Belury MA, Andridge R, Malarkey WB, Hwang BS, Glaser ROmega-3 supplementation lowers inflammation in healthy middle-aged and older adults: a randomized controlled trial.Brain Behav Immun 26(6) 988-95 8/1/2012
  • Bennett JM, Glaser M, Malarkey WB, Beversdorf DQ, Peng J, Kiecolt-Glaser JKInflammation and reactivation of latent herpesviruses in older adults.Brain Behav Immun 26(5) 739-46 7/1/2012
  • Fagundes CP, Glaser R, Johnson SL, Andridge RR, Yang EV, Di Gregorio MP, Chen M, Lambert DR, Jewell SD, Bechtel MA, Hearne DW, Herron JB, Kiecolt-Glaser JKBasal cell carcinoma: stressful life events and the tumor environment.Arch Gen Psychiatry 69(6) 618-26 6/1/2012
  • Alfano CM, Imayama I, Neuhouser ML, Kiecolt-Glaser JK, Wilder Smith A, Meeske K, McTiernan A, Bernstein L, Baumgartner KB, Ulrich CM, Ballard-Barbash RFatigue, inflammation, and ω-3 and ω-6 fatty acid intake among breast cancer survivors.J Clin Oncol 30(12) 1280-7 4/20/2012
  • Fagundes CP, Lindgren ME, Shapiro CL, Kiecolt-Glaser JKChild maltreatment and breast cancer survivors: social support makes a difference for quality of life, fatigue and cancer stress.Eur J Cancer 48(5) 728-36 3/1/2012
  • Gouin JP, Malarkey WB, Beversdorf D, Kiecolt-Glaser JK, Glaser MChronic stress, daily stressors, and circulating inflammatory markers.Health Psychol 31(2) 264-8 3/1/2012
  • Fagundes CP, Glaser R, Alfano CM, Bennett JM, Povoski SP, Lipari AM, Agnese DM, Yee LD, Carson WE 3rd, Farrar WB, Malarkey WB, Kiecolt-Glaser JKFatigue and herpesvirus latency in women newly diagnosed with breast cancer.Brain Behav Immun 26(3) 394-400 3/1/2012
  • Fagundes CP, Bennett JM, Alfano CM, Glaser R, Povoski SP, Lipari AM, Agnese DM, Yee LD, Carson WE, Farrar WB, Malarkey WB, Chen M, Kiecolt-Glaser JKSocial support and socioeconomic status interact to predict Epstein-Barr virus latency in women awaiting diagnosis or newly diagnosed with breast cancer.Health Psychol 31(1) 11-9 1/1/2012
  • Christian LM, Glaser M, Porter K, Malarkey WB, Beversdorf D, Kiecolt-Glaser JKPoorer self-rated health is associated with elevated inflammatory markers among older adults.Psychoneuroendocrinology 36(10) 1495-504 11/1/2011
  • Kiecolt-Glaser JK, Belury MA, Andridge R, Malarkey WB, Glaser ROmega-3 supplementation lowers inflammation and anxiety in medical students: a randomized controlled trial.Brain Behav Immun 25(8) 1725-34 11/1/2011
  • Fagundes CP, Bennett JM, Derry HM, Kiecolt-Glaser JKRelationships and Inflammation across the Lifespan: Social Developmental Pathways to Disease.Soc Personal Psychol Compass 5(11) 891-903 11/1/2011
  • Fagundes CP, Murray DM, Hwang BS, Gouin JP, Thayer JF, Sollers JJ 3rd, Shapiro CL, Malarkey WB, Kiecolt-Glaser JKSympathetic and parasympathetic activity in cancer-related fatigue: more evidence for a physiological substrate in cancer survivors.Psychoneuroendocrinology 36(8) 1137-47 9/1/2011