John Sheridan F PhD

John Sheridan F PhD
ProfessorCollege of Dentistrysheridan.1@osu.edu
231 Behavioral Med Research, Inst 460 Medical Center Drive Columbus Ohio 43210
Phone:614-293-3571Fax: (614) 292-6087
  • Cancer Control

General Research Interest

neuroendocrine regulation of inflammation and immunity 

Research Description

Dr. Sheridan's research focuses on understanding mind, brain and body interactions as they relate to modulation of peripheral physiological systems. This includes neuroendocrine regulation of gene expression in inflammatory and immune responses, and stress-induced susceptibility to infectious and malignant diseases.

Current Publications

  • Jung SH, Wang Y, Kim T, Tarr A, Reader B, Powell N, Sheridan JFMolecular Mechanisms of Repeated Social Defeat-Induced Glucocorticoid Resistance: Role of microRNA.Brain Behav Immun in press 10/12/2014
  • Wohleb ES, McKim DB, Shea DT, Powell ND, Tarr AJ, Sheridan JF, Godbout JPRe-establishment of anxiety in stress-sensitized mice is caused by monocyte trafficking from the spleen to the brain.Biol Psychiatry 75 970-81 6/15/2014
  • Wohleb ES, Patterson JM, Sharma V, Quan N, Godbout JP, Sheridan JFKnockdown of interleukin-1 receptor type-1 on endothelial cells attenuated stress-induced neuroinflammation and prevented anxiety-like behavior.J Neurosci 34 2583-91 2/12/2014
  • Powell ND, Sloan EK, Bailey MT, Arevalo JM, Miller GE, Chen E, Kobor MS, Reader BF, Sheridan JF, Cole SWSocial stress up-regulates inflammatory gene expression in the leukocyte transcriptome via β-adrenergic induction of myelopoiesis.Proc Natl Acad Sci U S A 110 16574-9 10/8/2013
  • Wohleb ES, Powell ND, Godbout JP, Sheridan JFStress-induced recruitment of bone marrow-derived monocytes to the brain promotes anxiety-like behavior.J Neurosci 33 13820-33 8/21/2013
  • Powell ND, Tarr AJ, Sheridan JFPsychosocial stress and inflammation in cancer.Brain Behav Immun 30 Suppl S41-7 3/1/2013
  • Rosenkranz MA, Davidson RJ, Maccoon DG, Sheridan JF, Kalin NH, Lutz AA comparison of mindfulness-based stress reduction and an active control in modulation of neurogenic inflammation.Brain Behav Immun 27 174-84 1/1/2013
  • Mo X, Sheridan JF, Eubank TD, Marsh CB, Voorhees JL, Tarr AJ, Wohleb ES, Godbout JPProlonged restraint stress increases IL-6, reduces IL-10, and causes persistent depressive-like behavior that is reversed by recombinant IL-10.PLoS One 8 e58488 1/1/2013
  • Chen Q, Tarr AJ, Liu X, Wang Y, Reed NS, Demarsh CP, Sheridan JF, Quan NControlled progressive innate immune stimulation regimen prevents the induction of sickness behavior in the open field test.J Inflamm Res 6 91-8 1/1/2013
  • Tarr AJ, Chen Q, Wang Y, Sheridan JF, Quan NNeural and behavioral responses to low-grade inflammation.Behav Brain Res 235 334-41 12/1/2012

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 300 W. 10th Ave. Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu