Janice K Kiecolt-Glaser PhD

Janice K Kiecolt-Glaser PhD
ProfessorOfc of Health Scienceskiecolt-glaser.1@osu.edu
130C Behavioral Med Research Inst 460 Medical Center Drive Columbus Ohio 43210
  • Cancer Control

General Research Interest

Behavioral influences on endocrine and immune function, diet, and health

Research Description

Dr. Janice Kiecolt-Glaser’s work addresses behavioral influences on immune and endocrine function.  Her current projects address how stress and depression enhance inflammation, and how dietary and behavioral interventions may lower inflammation. For example, two of her current randomized control trials, one with medical student subjects and another with older adults, are testing the hypothesis that omega-3 supplementation can attenuate stress-related changes in inflammation and mood.  Other current studies address questions such as how genetic and environmental influences contribute to depression and immune dysregulation in older adults, the impact of major life stressors on the progression of basal cell carcinoma, the extent to which a yoga intervention can modulate endocrine and immune responses in breast cancer survivors, and the role that proinflammatory cytokines play in combination with depression among cancer survivors who experience debilitating fatigue.

Transinstitutional Work

My research program has broad interdisciplinary collaborative ties. My primary collaborator on the immunological side is Dr. Ronald Glaser, the Director of the Institute for Behavioral Medicine Research. Our studies have important endocrine components because of the interface between the endocrine immune systems, with expertise provided by Dr. William Malarkey, Department of Medicine.  Some of our newer studies address the intersection of stress/depression, diet, and immune function, conducted in collaboration with Dr. Martha Belury, Department of Human Nutrition. Our collaborations with Dr. Charles Shapiro and Dr. Tanios Bekaii-Saab provide expertise in cancer biology related to breast and colorectal cancers. Dr. Stanley Lemeshow, the Dean of the College of Public Health, and Dr. David Murray, Director of the Division of Epidemiology in the College of Public Health, provide essential biostatistical expertise. Dr. Charles Emery in the Department of Psychology, College of Social and Behavioral Sciences, is a valued collaborator with expertise in exercise interventions. Dr. Dan Birmingham, Department of Medicine, has provided critical genetic expertise for studies with older adults. Trans--institutional collaborations include Dr. Catherine Alfano in the Office of Cancer Survivorship, National Cancer Institute. 

Current Publications

  • Kiecolt-Glaser JKCognitive problems among breast cancer survivors: loneliness enhances risk.Psychooncology 4/11/2014
  • Glaser RYoga's Impact on Inflammation, Mood, and Fatigue in Breast Cancer Survivors: A Randomized Controlled Trial.J Clin Oncol 32 1040-9 4/1/2014
  • Kiecolt-Glaser JKSocial support predicts inflammation, pain, and depressive symptoms: Longitudinal relationships among breast cancer survivors.Psychoneuroendocrinology 42 38-44 4/1/2014
  • Kiecolt-Glaser JKAttachment style and respiratory sinus arrhythmia predict post-treatment quality of life in breast cancer survivors.Psychooncology 2/17/2014
  • Derry HM, Fagundes CP, Andridge R, Glaser R, Malarkey WB, Kiecolt-Glaser JKLower subjective social status exaggerates interleukin-6 responses to a laboratory stressor.Psychoneuroendocrinology 38 2676-85 11/1/2013
  • Jaremka LM, Andridge RR, Fagundes CP, Alfano CM, Povoski SP, Lipari AM, Agnese DM, Arnold MW, Farrar WB, Yee LD, Carson WE, Bekaii-Saab T, Martin EW, Schmidt CR, Kiecolt-Glaser JKPain, Depression, and Fatigue: Loneliness as a Longitudinal Risk Factor.Health Psychol in press 8/19/2013
  • Lindgren ME, Fagundes CP, Alfano CM, Povoski SP, Agnese DM, Arnold MW, Farrar WB, Yee LD, Carson WE, Schmidt CR, Kiecolt-Glaser JKBeta-blockers may reduce intrusive thoughts in newly diagnosed cancer patients.Psychooncology 22(8) 1889-94 8/1/2013
  • Jaremka LM, Fagundes CP, Glaser R, Bennett JM, Malarkey WB, Kiecolt-Glaser JKLoneliness predicts pain, depression, and fatigue: understanding the role of immune dysregulation.Psychoneuroendocrinology 38(8) 1310-7 8/1/2013
  • Fagundes CP, Glaser R, Hwang BS, Malarkey WB, Kiecolt-Glaser JKDepressive symptoms enhance stress-induced inflammatory responses.Brain Behav Immun 31 172-6 7/1/2013
  • Jaremka LM, Fagundes CP, Peng J, Bennett JM, Glaser R, Malarkey WB, Kiecolt-Glaser JKLoneliness promotes inflammation during acute stress.Psychol Sci 24(7) 1089-97 7/1/2013
  • Hosang GM, Johnson SL, Kiecolt-Glaser J, Di Gregorio MP, Lambert DR, Bechtel MA, Hearne DW, Herron JB, Glaser RGender specific association of child abuse and adult cardiovascular disease in a sample of patients with basal cell carcinoma.Child Abuse Negl 37(6) 374-9 6/1/2013
  • Jaremka LM, Lindgren ME, Kiecolt-Glaser JKSynergistic relationships among stress, depression, and troubled relationships: insights from psychoneuroimmunology.Depress Anxiety 30(4) 288-96 4/1/2013
  • Jaremka LM, Glaser M, Loving TJ, Malarkey WB, Stowell JR, Kiecolt-Glaser JKAttachment anxiety is linked to alterations in cortisol production and cellular immunity.Psychol Sci 24(3) 272-9 3/1/2013
  • Fagundes CP, Glaser R, Malarkey WB, Kiecolt-Glaser JKChildhood adversity and herpesvirus latency in breast cancer survivors.Health Psychol 32(3) 337-44 3/1/2013
  • Kiecolt-Glaser JK, Epel ES, Belury M, Andridge R, Lin J, Glaser R, Malarkey WB, Hwang BS, Blackburn EOmega-3 fatty acids, oxidative stress, and leukocyte telomere length: A randomized controlled trial.Brain Behav Immun 28 16-24 2/1/2013
  • Bennett JM, Glaser R, Andridge RR, Peng J, Malarkey WB, Kiecolt-Glaser JKLong lasting effects of smoking: breast cancer survivors' inflammatory responses to acute stress differ by smoking history.Psychoneuroendocrinology 38(2) 179-87 2/1/2013
  • Fagundes CP, Glaser M, Kiecolt-Glaser JKStressful early life experiences and immune dysregulation across the lifespan.Brain Behav Immun 27(1) 8-12 1/1/2013
  • Kiecolt-Glaser JK, Christian LM, Andridge R, Hwang BS, Malarkey WB, Belury M, Emery CF, Glaser MAdiponectin, leptin, and yoga practice.Physiol Behav 107(5) 809-13 12/5/2012
  • Gouin JP, Glaser R, Malarkey WB, Beversdorf D, Kiecolt-Glaser JKChildhood abuse and inflammatory responses to daily stressors.Ann Behav Med 44(2) 287-92 10/1/2012
  • Gouin JP, Carter CS, Pournajafi-Nazarloo H, Malarkey WB, Loving TJ, Stowell J, Kiecolt-Glaser JKPlasma vasopressin and interpersonal functioning.Biol Psychol 91(2) 270-4 10/1/2012
  • Kiecolt-Glaser JK, Belury MA, Andridge R, Malarkey WB, Hwang BS, Glaser ROmega-3 supplementation lowers inflammation in healthy middle-aged and older adults: a randomized controlled trial.Brain Behav Immun 26(6) 988-95 8/1/2012
  • Bennett JM, Glaser M, Malarkey WB, Beversdorf DQ, Peng J, Kiecolt-Glaser JKInflammation and reactivation of latent herpesviruses in older adults.Brain Behav Immun 26(5) 739-46 7/1/2012
  • Fagundes CP, Glaser R, Johnson SL, Andridge RR, Yang EV, Di Gregorio MP, Chen M, Lambert DR, Jewell SD, Bechtel MA, Hearne DW, Herron JB, Kiecolt-Glaser JKBasal cell carcinoma: stressful life events and the tumor environment.Arch Gen Psychiatry 69(6) 618-26 6/1/2012

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 300 W. 10th Ave. Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu