Janice Kiecolt-Glaser K PhD

Janice Kiecolt-Glaser K PhD
ProfessorCollege of Medicinekiecolt-glaser.1@osu.edu
130C Behavioral Med Research Inst 460 Medical Center Drive Columbus Ohio 43210
  • Cancer Control

General Research Interest

Behavioral influences on endocrine and immune function, diet, and health

Research Description

Dr. Janice Kiecolt-Glaser’s work addresses behavioral influences on immune and endocrine function.  Her current projects address how stress and depression enhance inflammation, and how dietary and behavioral interventions may lower inflammation. For example, two of her current randomized control trials, one with medical student subjects and another with older adults, are testing the hypothesis that omega-3 supplementation can attenuate stress-related changes in inflammation and mood.  Other current studies address questions such as how genetic and environmental influences contribute to depression and immune dysregulation in older adults, the impact of major life stressors on the progression of basal cell carcinoma, the extent to which a yoga intervention can modulate endocrine and immune responses in breast cancer survivors, and the role that proinflammatory cytokines play in combination with depression among cancer survivors who experience debilitating fatigue.

Transinstitutional Work

My research program has broad interdisciplinary collaborative ties. My primary collaborator on the immunological side is Dr. Ronald Glaser, the Director of the Institute for Behavioral Medicine Research. Our studies have important endocrine components because of the interface between the endocrine immune systems, with expertise provided by Dr. William Malarkey, Department of Medicine.  Some of our newer studies address the intersection of stress/depression, diet, and immune function, conducted in collaboration with Dr. Martha Belury, Department of Human Nutrition. Our collaborations with Dr. Charles Shapiro and Dr. Tanios Bekaii-Saab provide expertise in cancer biology related to breast and colorectal cancers. Dr. Stanley Lemeshow, the Dean of the College of Public Health, and Dr. David Murray, Director of the Division of Epidemiology in the College of Public Health, provide essential biostatistical expertise. Dr. Charles Emery in the Department of Psychology, College of Social and Behavioral Sciences, is a valued collaborator with expertise in exercise interventions. Dr. Dan Birmingham, Department of Medicine, has provided critical genetic expertise for studies with older adults. Trans--institutional collaborations include Dr. Catherine Alfano in the Office of Cancer Survivorship, National Cancer Institute. 

Current Publications

  • Kiecolt-Glaser JK, Glaser R, Christian LMOmega-3 Fatty acids and stress-induced immune dysregulation: implications for wound healing.Mil Med 179 129-33 11/1/2014
  • Derry HM, Jaremka LM, Bennett JM, Peng J, Andridge R, Shapiro C, Malarkey WB, Emery CF, Layman R, Mrozek E, Glaser R, Kiecolt-Glaser JKYoga and self-reported cognitive problems in breast cancer survivors: a randomized controlled trial.Psychooncology in press 10/21/2014
  • Jaremka LM, Belury MA, Andridge RR, Malarkey WB, Glaser R, Christian L, Emery CF, Kiecolt-Glaser JKInterpersonal stressors predict ghrelin and leptin levels in women.Psychoneuroendocrinology 48 178-88 10/1/2014
  • Fagundes CP, Jaremka LM, Glaser R, Alfano CM, Povoski SP, Lipari AM, Agnese DM, Yee LD, Carson WE 3rd, Farrar WB, Malarkey WB, Chen M, Kiecolt-Glaser JKAttachment anxiety is related to Epstein-Barr virus latency.Brain Behav Immun 41 232-8 10/1/2014
  • Jaremka LM, Derry HM, Bornstein R, Prakash RS, Peng J, Belury MA, Andridge RR, Malarkey WB, Kiecolt-Glaser JKOmega-3 Supplementation and Loneliness-Related Memory Problems: Secondary Analyses of a Randomized Controlled Trial.Psychosom Med in press 9/26/2014
  • Jaremka LM, Andridge RR, Fagundes CP, Alfano CM, Povoski SP, Lipari AM, Agnese DM, Arnold MW, Farrar WB, Yee LD, Carson WE, Bekaii-Saab T, Martin EW, Schmidt CR, Kiecolt-Glaser JKPain, depression, and fatigue: Loneliness as a longitudinal risk factor.Health Psychol 33 948-57 9/1/2014
  • Kiecolt-Glaser JK, Habash DL, Fagundes CP, Andridge R, Peng J, Malarkey WB, Belury MADaily Stressors, Past Depression, and Metabolic Responses to High-Fat Meals: A Novel Path to Obesity.Biol Psychiatry in press 7/9/2014
  • Fagundes CP, Jaremka LM, Malarkey WB, Kiecolt-Glaser JKAttachment style and respiratory sinus arrhythmia predict post-treatment quality of life in breast cancer survivors.Psychooncology 23 820-6 7/1/2014
  • Kiecolt-Glaser JK, Jaremka LM, Hughes SPsychiatry and social nutritional neuroscience.World Psychiatry 13 6/1/2014
  • Jaremka LM, Peng J, Povoski SP, Lipari AM, Agnese DM, Farrar WB, Yee LD, Carson WE 3rd, Bornstein R, Alfano CM, Andridge RR, Kiecolt-Glaser JKCognitive problems among breast cancer survivors: loneliness enhances risk.Psychooncology in press 4/11/2014
  • Kiecolt-Glaser JK, Bennett JM, Andridge R, Peng J, Shapiro CL, Malarkey WB, Emery CF, Layman R, Mrozek EE, Glaser RYoga's impact on inflammation, mood, and fatigue in breast cancer survivors: a randomized controlled trial.J Clin Oncol 32 1040-9 4/1/2014
  • Hughes S, Jaremka LM, Alfano CM, Glaser R, Povoski SP, Lipari AM, Agnese DM, Farrar WB, Yee LD, Carson WE 3rd, Malarkey WB, Kiecolt-Glaser JKSocial support predicts inflammation, pain, and depressive symptoms: longitudinal relationships among breast cancer survivors.Psychoneuroendocrinology 42 38-44 4/1/2014
  • Kiecolt-Glaser JK, Jaremka LM, Derry HM, Glaser RTelomere length: a marker of disease susceptibility?Brain Behav Immun 34 29-30 11/1/2013
  • Jaremka LM, Glaser R, Malarkey WB, Kiecolt-Glaser JKMarital distress prospectively predicts poorer cellular immune function.Psychoneuroendocrinology 38 2713-9 11/1/2013
  • Derry HM, Fagundes CP, Andridge R, Glaser R, Malarkey WB, Kiecolt-Glaser JKLower subjective social status exaggerates interleukin-6 responses to a laboratory stressor.Psychoneuroendocrinology 38 2676-85 11/1/2013
  • Jaremka LM, Fagundes CP, Glaser R, Bennett JM, Malarkey WB, Kiecolt-Glaser JKLoneliness predicts pain, depression, and fatigue: understanding the role of immune dysregulation.Psychoneuroendocrinology 38 1310-7 8/1/2013
  • Lindgren ME, Fagundes CP, Alfano CM, Povoski SP, Agnese DM, Arnold MW, Farrar WB, Yee LD, Carson WE, Schmidt CR, Kiecolt-Glaser JKBeta-blockers may reduce intrusive thoughts in newly diagnosed cancer patients.Psychooncology 22 1889-94 8/1/2013
  • Fagundes CP, Glaser R, Hwang BS, Malarkey WB, Kiecolt-Glaser JKDepressive symptoms enhance stress-induced inflammatory responses.Brain Behav Immun 31 172-6 7/1/2013
  • Jaremka LM, Fagundes CP, Peng J, Bennett JM, Glaser R, Malarkey WB, Kiecolt-Glaser JKLoneliness promotes inflammation during acute stress.Psychol Sci 24 1089-97 7/1/2013
  • Hosang GM, Johnson SL, Kiecolt-Glaser J, Di Gregorio MP, Lambert DR, Bechtel MA, Hearne DW, Herron JB, Glaser RGender specific association of child abuse and adult cardiovascular disease in a sample of patients with basal cell carcinoma.Child Abuse Negl 37 374-9 6/1/2013
  • Jaremka LM, Lindgren ME, Kiecolt-Glaser JKSynergistic relationships among stress, depression, and troubled relationships: insights from psychoneuroimmunology.Depress Anxiety 30 288-96 4/1/2013
  • Fagundes CP, Glaser R, Malarkey WB, Kiecolt-Glaser JKChildhood adversity and herpesvirus latency in breast cancer survivors.Health Psychol 32 337-44 3/1/2013
  • Jaremka LM, Glaser R, Loving TJ, Malarkey WB, Stowell JR, Kiecolt-Glaser JKAttachment anxiety is linked to alterations in cortisol production and cellular immunity.Psychol Sci 24 272-9 3/1/2013
  • Kiecolt-Glaser JK, Epel ES, Belury MA, Andridge R, Lin J, Glaser R, Malarkey WB, Hwang BS, Blackburn EOmega-3 fatty acids, oxidative stress, and leukocyte telomere length: A randomized controlled trial.Brain Behav Immun 28 16-24 2/1/2013
  • Andridge RR, Peng J, Malarkey WB, Kiecolt-Glaser JK, Bennett JM, Glaser RLong lasting effects of smoking: breast cancer survivors' inflammatory responses to acute stress differ by smoking history.Psychoneuroendocrinology 38 179-87 2/1/2013
  • Fagundes CP, Glaser R, Kiecolt-Glaser JKStressful early life experiences and immune dysregulation across the lifespan.Brain Behav Immun 27 8-12 1/1/2013

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 460 W. 10th Avenue, Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu