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Michael A. Pereira PhD

Michael A. Pereira PhD
Faculty EmeritusCollege of Medicinemichael.pereira@osumc.edu
1148B James Cancer Hosp & Res Inst 300 W 10th Avenue Columbus OH 43210
Phone:614-293-6864Fax: 614-293-4072
  • Molecular Carcinogenesis and Chemoprevention

General Research Interest

Cancer Chemoprevention, Chemical Carcinogenesis, Epigenetic Mechanisms

Research Description

Current research involves identification of new chemopreventive agents, and determination of their efficacy and mechanism of action. The identification and determination of the efficacy of new chemopreventive agents has focused on drugs including NSAIDs, retinoids, and HDAC inhibitors. The efficacy studies have also focused on the use of combinations of chemopreventive agents administered either together or sequentially. The mechanism studies are determining the mechanism by which chemopreventive agents slow the progression to cancer. These studies have mainly investigated epigenetic mechanisms.

Transinstitutional Work

None.

Current Publications

  • Pereira MA, Warner BM, Knobloch TJ, Weghorst CM, Lubet RA, Steele VE, Casto BCChemoprevention of mouse lung and colon tumors by suberoylanilide hydroxamic acid and atorvastatin.Int J Cancer 131(6) 1277-86 9/15/2012
  • Lubet RA, Clapper ML, McCormick DL, Pereira MA, Chang WC, Steele VE, Fischer SM, Juliana MM, Grubbs CJChemopreventive efficacy of Targretin in rodent models of urinary bladder, colon/intestine, head and neck and mammary cancers.Oncol Rep 27(5) 1400-6 5/1/2012
  • Casto BC, Pereira MAPrevention of mouse lung tumors by combinations of chemopreventive agents using concurrent and sequential administration.Anticancer Res 31(10) 3279-84 10/1/2011