Steven Schwartz J PhD

Steven Schwartz J PhD
ProfessorColl of Food, Agr,Envir Scienceschwartz.177@osu.edu
110 Parker Food Sci&Technology Bld 2015 Fyffe Court Columbus Ohio 43210
Phone:614-292-2934Fax: (614) 292-4233
  • Molecular Carcinogenesis and Chemoprevention

Research Description

Dr. Schwartz' research interests include: • Metabolic profiling, targeted and untargeted metabolomics related to food and nutrition for health; Bioavailability, metabolism, and physiological significance of carotenoids, isothiocyanates, isoflavones and other phytochemicals; Phytochemicals and bioactive components in foods related to chronic disease, oxidative stress and cancer prevention and control; Analytical methods development in food analysis; Chemistry of plant pigments, particularly chlorophylls, carotenoids, and provitamin A nutrients; and Chemical alterations of food components during processing with emphasis on substances of nutritional, toxicological and food quality significance.

Current Publications

  • Kopec RE, Cooperstone JL, Schweiggert RM, Young GS, Harrison EH, Francis DM, Clinton SK, Schwartz SJAvocado Consumption Enhances Human Postprandial Provitamin A Absorption and Conversion from a Novel High-β-Carotene Tomato Sauce and from Carrots.J Nutr 144 1158-66 8/1/2014
  • Mace TA, King SA, Ameen Z, Elnaggar O, Young G, Riedl KM, Schwartz SJ, Clinton SK, Knobloch TJ, Weghorst CM, Lesinski GBBioactive compounds or metabolites from black raspberries modulate T lymphocyte proliferation, myeloid cell differentiation and Jak/STAT signaling.Cancer Immunol Immunother in press 6/4/2014
  • dela Seña C, Riedl KM, Narayanasamy S, Curley RW Jr, Schwartz SJ, Harrison EHThe human enzyme that converts dietary provitamin A carotenoids to vitamin A is a dioxygenase.J Biol Chem 289 13661-6 5/9/2014
  • Tan HL, Moran NE, Cichon MJ, Riedl KM, Schwartz SJ, Erdman JW Jr, Pearl DK, Thomas-Ahner JM, Clinton SKβ-Carotene-9',10'-oxygenase status modulates the impact of dietary tomato and lycopene on hepatic nuclear receptor-, stress-, and metabolism-related gene expression in mice.J Nutr 144 431-9 4/1/2014
  • Esquivel P, Schwartz SJ, Carle R, Schweiggert RM, Kopec RE, Villalobos-Gutierrez MG, Högel J, Quesada SCarotenoids are more bioavailable from papaya than from tomato and carrot in humans: a randomised cross-over study.Br J Nutr 111 490-8 2/1/2014
  • Gu J, Ahn-Jarvis JH, Riedl KM, Schwartz SJ, Clinton SK, Vodovotz YCharacterization of Black Raspberry Functional Food Products for Cancer Prevention Human Clinical Trials.J Agric Food Chem in press 12/27/2013
  • dela Seña C, Narayanasamy S, Riedl KM, Curley RW Jr, Schwartz SJ, Harrison EHSubstrate specificity of purified recombinant human β-carotene 15,15'-oxygenase (BCO1).J Biol Chem 288 37094-103 12/27/2013
  • Li Y, Zhang T, Li X, Zou P, Schwartz SJ, Sun DKinetics of sulforaphane in mice after consumption of sulforaphane-enriched broccoli sprout preparation.Mol Nutr Food Res 57 2128-36 12/1/2013
  • Hostetler GL, Riedl KM, Schwartz SJEffects of food formulation and thermal processing on flavones in celery and chamomile.Food Chem 141 1406-11 11/15/2013
  • Riedl KM, Choksi K, Wyzgoski FJ, Scheerens JC, Schwartz SJ, Reese RNVariation in lycopene and lycopenoates, antioxidant capacity, and fruit quality of buffaloberry (Shepherdia argentea [Pursh]Nutt.).J Food Sci 78 C1673-9 11/1/2013
  • Yezbick G, Ahn-Jarvis J, Schwartz SJ, Vodovotz YPhysicochemical characterization and sensory analysis of yeast-leavened and sourdough soy breads.J Food Sci 78 C1487-94 10/1/2013
  • Serventi L, Chitchumroonchokchai C, Riedl KM, Kerem Z, Berhow MA, Vodovotz Y, Schwartz SJ, Failla MLSaponins from soy and chickpea: stability during beadmaking and in vitro bioaccessibility.J Agric Food Chem 61 6703-10 7/10/2013
  • Kopec RE, Schweiggert RM, Riedl KM, Carle R, Schwartz SJComparison of high-performance liquid chromatography/tandem mass spectrometry and high-performance liquid chromatography/photo-diode array detection for the quantitation of carotenoids, retinyl esters, α-tocopherol and phylloquinone in chylomicron-rich fractions of human plasma.Rapid Commun Mass Spectrom 27 1393-402 6/30/2013
  • Ahn-Jarvis JH, Riedl KM, Schwartz SJ, Vodovotz YDesign and selection of soy breads used for evaluating isoflavone bioavailability in clinical trials.J Agric Food Chem 61 3111-20 3/27/2013
  • Bohn T, Blackwood M, Francis D, Tian Q, Schwartz SJ, Clinton SKBioavailability of phytochemical constituents from a novel soy fortified lycopene rich tomato juice developed for targeted cancer prevention trials.Nutr Cancer 65 919-29 1/1/2013
  • Li Y, Karagöz GE, Seo YH, Zhang T, Jiang Y, Yu Y, Duarte AM, Schwartz SJ, Boelens R, Carroll K, Rüdiger SG, Sun DSulforaphane inhibits pancreatic cancer through disrupting Hsp90-p50(Cdc37) complex and direct interactions with amino acids residues of Hsp90.J Nutr Biochem 23 1617-26 12/1/2012
  • Ferruzzi MG, Peterson DG, Singh RP, Schwartz SJ, Freedman MRNutritional translation blended with food science: 21st century applications.Adv Nutr 3 813-9 11/1/2012
  • Abbaoui B, Riedl KM, Ralston RA, Thomas-Ahner JM, Schwartz SJ, Clinton SK, Mortazavi AInhibition of bladder cancer by broccoli isothiocyanates sulforaphane and erucin: characterization, metabolism, and interconversion.Mol Nutr Food Res 56 1675-87 11/1/2012
  • Ahn-Jarvis J, Clinton SK, Riedl KM, Vodovotz Y, Schwartz SJImpact of food matrix on isoflavone metabolism and cardiovascular biomarkers in adults with hypercholesterolemia.Food Funct 3 1051-8 10/1/2012

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 300 W. 10th Ave. Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu