Altaf Wani A. PhD

Altaf Wani A. PhD
ProfessorCollege of Medicinewani.2@osu.edu
736 Biomedical Research Tower 460 W 12th Avenue Columbus Ohio 43210
Phone:614-292-9015Fax:
  • Molecular Carcinogenesis and Chemoprevention

Research Description

Dr. Wani's research interests include Molecular carcinogenesis-analysis, fine mapping and cellular processing of specific genotoxic base lesions, mutagenesis, apoptosis and other DNA damage responses.

Current Publications

  • Zhao R, Han C, Eisenhauer E, Kroger J, Zhao W, Yu J, Selvendiran K, Liu X, Wani AA, Wang QEDNA damage-binding complex recruits HDAC1 to repress Bcl-2 transcription in human ovarian cancer cells.Mol Cancer Res 12 370-80 3/1/2014
  • Sharma N, Zhu Q, Wani G, He J, Wang QE, Wani AAUSP3 counteracts RNF168 via deubiquitinating H2A and γH2AX at lysine 13 and 15.Cell Cycle 13 106-14 1/1/2014
  • Ray A, Milum K, Battu A, Wani G, Wani AANER initiation factors, DDB2 and XPC, regulate UV radiation response by recruiting ATR and ATM kinases to DNA damage sites.DNA Repair (Amst) 12 273-83 4/1/2013
  • Wang QE, Han C, Zhao R, Wani G, Zhu Q, Gong L, Battu A, Racoma I, Sharma N, Wani AAp38 MAPK- and Akt-mediated p300 phosphorylation regulates its degradation to facilitate nucleotide excision repair.Nucleic Acids Res 41 1722-33 2/1/2013
  • Han C, Zhao R, Kroger J, Qu M, Wani AA, Wang QECaspase-2 short isoform interacts with membrane-associated cytoskeleton proteins to inhibit apoptosis.PLoS One 8 e67033 1/1/2013
  • Racoma IO, Meisen WH, Wang QE, Kaur B, Wani AAThymoquinone inhibits autophagy and induces cathepsin-mediated, caspase-independent cell death in glioblastoma cells.PLoS One 8 e72882 1/1/2013
  • Zhu Q, Wani G, Sharma N, Wani ALack of CAK complex accumulation at DNA damage sites in XP-B and XP-B/CS fibroblasts reveals differential regulation of CAK anchoring to core TFIIH by XPB and XPD helicases during nucleotide excision repair.DNA Repair (Amst) 11 942-50 12/1/2012

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 300 W. 10th Ave. Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu