Bruce C Casto Dr Sc

Bruce C Casto Dr Sc
Senior Res ScientistCollege of Public Healthcasto.44@osu.edu
400B-2 Cunz Hall 1841 Neil Avenue Columbus Ohio 43210
Phone:614-688-4342Fax: 614-293-7710
  • Molecular Carcinogenesis and Chemoprevention

General Research Interest

Preclinical studies of whole foods as preventives for oral cancer.  Gender differences in lung cancer. Use of therapeutic drugs for prevention of lung and colon cancer in animal models.  In vitro studies of chemopreventive agents for inhibition of cell proliferation and induction of apoptosis.  Quantitation of respiratory viruses in aerosols and their inactivation by UV.  

Research Description

Conduct of bioassays for carcinogens in cell culture and in experimental animal models.  Chemoprevention of oral, colon, and lung cancer by natural food products.  Association between polycyclic hydrocarbon exposure and breast cancer induction by estrogens.  Modulation of xenotransplanted human tumors by nonsteroidal anti-inflammatory agents.  In vitro assays of genotoxicity by environmental and occupational chemicals. 

Transinstitutional Work

None

Current Publications

  • Casto BC, Knobloch TJ, Galioto RL, Yu Z, Accurso BT, Warner BMChemoprevention of oral cancer by lyophilized strawberries.Anticancer Res 33 4757-66 11/1/2013
  • Pereira MA, Warner BM, Knobloch TJ, Weghorst CM, Lubet RA, Steele VE, Casto BCChemoprevention of mouse lung and colon tumors by suberoylanilide hydroxamic acid and atorvastatin.Int J Cancer 131(6) 1277-86 9/15/2012

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 300 W. 10th Ave. Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu