Junan Li PhD

Junan Li PhD
Res ScientistCollege of Pharmacyli.225@osu.edu
230 Parks Hall 500 W 12th Avenue Columbus Ohio 43210
Phone:614-688-4370Fax: 614-292-4053
  • Non-Member

General Research Interest

Molecular mechanisms underlying environmentally-induced cancers and its prevention

Research Description

 (1) Structure-function relationship of oncogens and tumor suppressors;  (2) Biomarkers in the early stage of oral cancer progression;  (3) Biophysical and biophysical properties of ankyrin repeat proteins.

Transinstitutional Work

(1) In collaboration with Dr. Weghorst to identify biomarkers in the early stage of oral cancer progression;  (2) In collaboration with a group of PIs in OSU CCC (headed by Drs. Weghorst and Clinton) to indentify natural products with potential in chemopreventation of oral cancers.

Current Publications

  • Li JAlterations in RDINK4/ARF -mediated en bloc regulation of the INK4-ARF locus in human squamous cell carcinoma of the head and neck.Mol Carcinog 12/2/2013
  • Yuan C, Guo Y, Zhu L, Guo W, Mahajan A, Weghorst CM, Li JThe Study of pH-Dependent Stability Shows that the TPLH-Mediated Hydrogen-Bonding Network Is Important for the Conformation and Stability of Human Gankyrin.Biochemistry in press 7/8/2013
  • Poi MJ, Knobloch TJ, Yuan C, Tsai MD, Weghorst CM, Li JEvidence that P12, a specific variant of P16(INK4A), plays a suppressive role in human pancreatic carcinogenesis.Biochem Biophys Res Commun 436(2) 217-22 6/28/2013
  • Li J, Knobloch TJ, Poi MJ, Zhang Z, Davis AT, Muscarella P, Weghorst CMGenetic alterations of RD(INK4/ARF) enhancer in human cancer cells.Mol Carcinog in press 10/12/2012

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 300 W. 10th Ave. Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu