Martha Belury PhD

Martha Belury PhD
ProfessorCollege of Education & Human
302 Campbell Hall 1787 Neil Avenue Columbus Ohio 43210
  • Molecular Carcinogenesis and Chemoprevention

General Research Interest

Role of dietary fat quality in modulating macronutrient metabolism; obesity, type diabetes, metabolic syndrome and cancer cachexia

Research Description

Dr. Belury and her lab are interested in the study of whole body energy metabolism as regulated by interactions between adipose and muscle tissues.   Canonical mechanisms of energy metabolism involve insulin-dependent and –independent pathways in each of these tissues. In addition, adipose secretes adipokines that regulate metabolism and inflammation in non-adipose tissues. We seek to understand how the availability or lack of availability of energy substrates and bioactive compounds (e.g.,  adipokines and dietary components) modulate metabolism and tissue function of adipose and muscle. Energy deprivation induces atrophy of muscle and adipose using some overlapping mechanisms including altered metabolism, inflammation, proteolysis and cell death-associated signals.  Our work with muscle involves identifying the steps of atrophy related to insulin-resistance, proteolysis and cell death.  

Transinstitutional Work

Cancer center, Davis Heart and Lung Institute, OSUMC, CRC-CTSA

Current Publications

  • Ke JY, Tian M, Cole RM, Andridge RR, Belury MA, Kliewer KLAdipose tissue lipolysis and energy metabolism in early cancer cachexia in mice.Cancer Biol Ther in press 12/2/2014
  • Jaremka LM, Belury MA, Andridge RR, Malarkey WB, Glaser R, Christian L, Emery CF, Kiecolt-Glaser JKInterpersonal stressors predict ghrelin and leptin levels in women.Psychoneuroendocrinology 48 178-88 10/1/2014
  • Jaremka LM, Derry HM, Bornstein R, Prakash RS, Peng J, Belury MA, Andridge RR, Malarkey WB, Kiecolt-Glaser JKOmega-3 Supplementation and Loneliness-Related Memory Problems: Secondary Analyses of a Randomized Controlled Trial.Psychosom Med in press 9/26/2014
  • Kiecolt-Glaser JK, Habash DL, Fagundes CP, Andridge R, Peng J, Malarkey WB, Belury MADaily Stressors, Past Depression, and Metabolic Responses to High-Fat Meals: A Novel Path to Obesity.Biol Psychiatry in press 7/9/2014
  • Carta G, Murru E, Cordeddu L, Ortiz B, Giordano E, Belury MA, Quadro L, Banni SMetabolic Interactions between vitamin A and conjugated linoleic acid.Nutrients 6 1262-72 1/1/2014
  • Liu MJ, Bao S, Bolin ER, Burris DL, Xu X, Sun Q, Killilea DW, Shen Q, Ziouzenkova O, Belury MA, Failla ML, Knoell DLZinc deficiency augments leptin production and exacerbates macrophage infiltration into adipose tissue in mice fed a high-fat diet.J Nutr 143 1036-45 7/1/2013
  • Orchard TS, Ing SW, Lu B, Belury MA, Johnson K, Wactawski-Wende J, Jackson RDThe association of red blood cell n-3 and n-6 fatty acids with bone mineral density and hip fracture risk in the women's health initiative.J Bone Miner Res 28 505-15 3/1/2013
  • Kiecolt-Glaser JK, Epel ES, Belury MA, Andridge R, Lin J, Glaser R, Malarkey WB, Hwang BS, Blackburn EOmega-3 fatty acids, oxidative stress, and leukocyte telomere length: A randomized controlled trial.Brain Behav Immun 28 16-24 2/1/2013
  • Yee LD, Agarwal D, Rosol TJ, Lehman A, Tian M, Hatton J, Heestand J, Belury MA, Clinton SKThe inhibition of early stages of HER-2/neu-mediated mammary carcinogenesis by dietary n-3 PUFAs.Mol Nutr Food Res 57 320-7 2/1/2013

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 460 W. 10th Avenue, Columbus, OH 43210 Phone: 1-800-293-5066 | Email: