Traci Wilgus A PhD

Traci Wilgus A PhD
Asst ProfessorCollege of Medicinewilgus.3@osu.edu
M364B Starling Loving Hall 320 W 10th Avenue Columbus Ohio 43210
Phone:614-366-8526Fax: (614) 366-9389
  • Molecular Carcinogenesis and Chemoprevention

General Research Interest

Our laboratory is interested in understanding how inflammation and angiogenesis contribute to non-melanoma skin cancer.

Research Description

Dr. Wilgus studies the involvement of the pro-angiogenic growth factor vascular endothelial growth factor (VEGF) in skin carcinogenesis. VEGF is known to contribute to skin carcinogenesis by enhancing angiogenesis. Her lab has found that VEGFR-1 (VEGF receptor-1) is expressed by normal epidermal keratinocytes and tumor cells from non-melanoma skin cancers. Studies are underway to determine whether VEGF can directly influence these cells by signaling through VEGFR-1, and the potential importance of epithelial VEGFR-1 signaling for the growth and development of skin tumors.

Current Publications

  • Johnson KE, Wilgus TAVascular Endothelial Growth Factor and Angiogenesis in the Regulation of Cutaneous Wound Repair.Adv Wound Care (New Rochelle) 3 647-661 10/1/2014
  • Johnson KE, Wulff BC, Oberyszyn TM, Wilgus TAUltraviolet light exposure stimulates HMGB1 release by keratinocytes.Arch Dermatol Res 305 805-15 11/1/2013
  • Wulff BC, Wilgus TAMast cell activity in the healing wound: more than meets the eye?Exp Dermatol 22 507-10 8/1/2013
  • McDaniel JC, Roy S, Wilgus TANeutrophil activity in chronic venous leg ulcers--a target for therapy?Wound Repair Regen 21 339-51 5/1/2013
  • Dardenne AD, Wulff BC, Wilgus TAThe alarmin HMGB-1 influences healing outcomes in fetal skin wounds.Wound Repair Regen 21 282-91 3/1/2013
  • Yeh ST, Aune SE, Wilgus TA, Parent AE, Angelos MGHyperoxemic reperfusion after prolonged cardiac arrest in a rat cardiopulmonary bypass resuscitation model.Resuscitation 84 114-20 1/1/2013
  • Wulff BC, Yu L, Parent AE, Wilgus TANovel differences in the expression of inflammation-associated genes between mid- and late-gestational dermal fibroblasts.Wound Repair Regen 21 103-12 1/1/2013

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 300 W. 10th Ave. Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu