Yael Vodovotz PhD

Yael Vodovotz PhD
ProfessorColl of Food, Agr,Envir Sciencevodovotz.1@osu.edu
227 Parker Food Sci&Technology Bld 2015 Fyffe Court Columbus Ohio 43210
  • Molecular Carcinogenesis and Chemoprevention

General Research Interest

Physico-chemical properties of food materials and specifically phytochemical delivery systems

Research Description

My research focus is the physico-chemical changes of functional foods during formulation, processing and storage as they impact the delivery of bioactives. We utilize molecular, structural and macroscopic analysis to fully characterize food material behavior in different conditions and subsequently can modify these products to deliver bioactives to targeted organs.

Transinstitutional Work

Most of our work is significantly enhanced by the various collaborators on the projects. We have worked with soy both in a soy-tomato drink and a soy bread. Our contribution was to optimize product quality while maintaining phytochemical stability and optimal delivery. Both products required extensive collaborations with the Medical School (phase I and II clinical trials), Human Nutrition (understanding the stability of phytochemicals during the digestive process as well as cell proliferation), Crop and Soil Science (to obtain optimal phytochemical profiles in the ingredients used to make the products) and Agricultural, Environmental and Development Economics (to study how marketable the products are to the average consumer). A similar approach was used in the development of functional fruit confections. A key collaborator was the College of Public Health since these confections are intended for possible prevention and treatment of oral cancer. Additionally, the College of Pharmacy was critical in lending their expertise to optimize dissolution and delivery rates of the phytochemicals.

Current Publications

  • Vodovotz YCharacterization of Black Raspberry Functional Food Products for Cancer Prevention Human Clinical Trials.J Agric Food Chem 12/27/2013
  • Ahn-Jarvis J, Clinton SK, Riedl KM, Vodovotz Y, Schwartz SJImpact of food matrix on isoflavone metabolism and cardiovascular biomarkers in adults with hypercholesterolemia.Food Funct 3(10) 1051-8 10/1/2012

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 300 W. 10th Ave. Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu