Craig Burd J PhD

Craig Burd J PhD
Asst ProfessorArts and Sciencesburd.7@osu.edu
590 Biomedical Research Tower 460 W 12th Avenue Columbus Ohio 43210
Phone:614-688-7458Fax: (614) 292-4466
  • Molecular Carcinogenesis and Chemoprevention

General Research Interest

The understanding of molecular mechanisms by which environmental agents can influence hormonal signaling and tumorigenesis.

Research Description

Dr. Burd's lab focuses on the signaling of estrogen through its cognate receptor, the estrogen receptor. Estrogen signaling plays a central role in breast cancer development and progression and deregulated activity influences therapeutic relapse. In the lab, the aim is to understand the molecular mechanisms controlling the estrogen receptor’s activity and potentially how these mechanisms, when not properly maintained, influence breast cancer risk and therapeutic relapse. One of the core interests in the lab is to characterize the potential of environmental chemicals, called endocrine disruptors, to influence breast cancer risk.

Current Publications

  • Young NA, Wu LC, Burd CJ, Friedman AK, Kaffenberger BH, Rajaram MV, Schlesinger LS, James H, Shupnik MA, Jarjour WNEstrogen modulation of endosome-associated toll-like receptor 8: an IFNα-independent mechanism of sex-bias in systemic lupus erythematosus.Clin Immunol 151 66-77 3/1/2014
  • Burd CJ, Archer TKChromatin architecture defines the glucocorticoid response.Mol Cell Endocrinol 380 25-31 11/5/2013
  • Augello MA, Burd CJ, Birbe R, McNair C, Ertel A, Magee MS, Frigo DE, Wilder-Romans K, Shilkrut M, Han S, Jernigan DL, Dean JL, Fatatis A, McDonnell DP, Visakorpi T, Feng FY, Knudsen KEConvergence of oncogenic and hormone receptor pathways promotes metastatic phenotypes.J Clin Invest 123 493-508 1/2/2013

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 300 W. 10th Ave. Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu