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Michael V. Knopp MD, PhD

Michael V. Knopp MD, PhD
ProfessorCollege of Medicinemichael.knopp@osumc.edu
430 12th Avenue Hall 395 W 12th Avenue Columbus OH 43210
Phone:614-293-9998Alternate Phone:614-293-9227Fax: 614-293-9275
  • Experimental Therapeutics

General Research Interest

Oncological imaging for detection of disease characterization, staging, therapy planning and response assessment; imaging-based assessment of neoangiogenesis; imaging biomarker; semi-quantitative imaging

Research Description

The broad research activities focus on imaging biomarker for disease characterization and response assessment, imaging technology development and validation, imaging biomarker development and validation.

Transinstitutional Work

The research projects are consolidated under the Wright Center of Innovation in Biomedical Imaging which is a unique trans-institutional, interdisciplinary, academia/industry imaging technology development service and commercialization environment. Collaboration in all areas of health and biological sciences and engineering, arts and sciences and business are ongoing.

Current Publications

  • Povoski SP, Hall NC, Murrey DA Jr, Sharp DS, Hitchcock CL, Mojzisik CM, Bahnson EE, Knopp MV, Martin EW Jr, Bahnson RRMultimodal imaging and detection strategy with 124 I-labeled chimeric monoclonal antibody cG250 for accurate localization and confirmation of extent of disease during laparoscopic and open surgical resection of clear cell renal cell carcinoma.Surg Innov 20(1) 59-69 2/1/2013
  • Fitzgerald TJ, Bishop-Jodoin M, Bosch WR, Curran WJ, Followill DS, Galvin JM, Hanusik R, King SR, Knopp MV, Laurie F, O'Meara E, Michalski JM, Saltz JH, Schnall MD, Schwartz L, Ulin K, Xiao Y, Urie MFuture vision for the quality assurance of oncology clinical trials.Front Oncol 3 31 1/1/2013
  • Martin LK, Grecula J, Jia G, Wei L, Yang X, Otterson GA, Wu X, Harper E, Kefauver C, Zhou BS, Yen Y, Bloomston M, Knopp M, Ivy SP, Grever M, Bekaii-Saab TA dose escalation and pharmacodynamic study of triapine and radiation in patients with locally advanced pancreas cancer.Int J Radiat Oncol Biol Phys 84(4) e475-81 11/15/2012
  • Yang X, Mrozek E, Lustberg M, Jia G, Sammet S, Sammet C, Shapiro C, Knopp MVMicrocirculatory fraction (MCF(I)) as a potential imaging marker for tumor heterogeneity in breast cancer.Magn Reson Imaging 30(8) 1059-67 10/1/2012
  • Mayr NA, Huang Z, Wang JZ, Lo SS, Fan JM, Grecula JC, Sammet S, Sammet CL, Jia G, Zhang J, Knopp MV, Yuh WTCharacterizing tumor heterogeneity with functional imaging and quantifying high-risk tumor volume for early prediction of treatment outcome: cervical cancer as a model.Int J Radiat Oncol Biol Phys 83(3) 972-9 7/1/2012
  • Povoski SP, Hall NC, Murrey DA Jr, Chow AZ, Gaglani JR, Bahnson EE, Mojzisik CM, Kuhrt MP, Hitchcock CL, Knopp MV, Martin EW JrMultimodal imaging and detection approach to 18F-FDG-directed surgery for patients with known or suspected malignancies: a comprehensive description of the specific methodology utilized in a single-institution cumulative retrospective experience.World J Surg Oncol 9 152 11/23/2011
  • Christoforidis JB, Carlton MM, Knopp MV, Hinkle GHPET/CT imaging of I-124-radiolabeled bevacizumab and ranibizumab after intravitreal injection in a rabbit model.Invest Ophthalmol Vis Sci 52(8) 5899-903 7/29/2011