Rath KS, McCann GA, Cohn DE, Rivera BK, Kuppusamy P, Selvendiran KSafe and targeted anticancer therapy for ovarian cancer using a novel class of curcumin analogs.J Ovarian Res in press 5/11/2013
Madan E, Gogna R, Kuppusamy P, Bhatt M, Mahdi AA, Pati USCO2 induces p53-mediated apoptosis by Thr845 phosphorylation of ASK-1 and dissociation of the ASK-1-Trx complex.Mol Cell Biol 33(7) 1285-302 4/1/2013
Tierney BJ, McCann GA, Cohn DE, Eisenhauer E, Sudhakar M, Kuppusamy P, Hideg K, Selvendiran KHO-3867, a STAT3 inhibitor induces apoptosis by inactivation of STAT3 activity in BRCA1-mutated ovarian cancer cells.Cancer Biol Ther 13(9) 766-75 7/1/2012
Gogna R, Madan E, Kuppusamy P, Pati UReactive oxygen species-mediated p53 core-domain modifications determine apoptotic or necrotic death in cancer cells.Antioxid Redox Signal 16(5) 400-12 3/1/2012
Gogna R, Madan E, Kuppusamy P, Pati UChaperoning of mutant p53 protein by wild-type p53 protein causes hypoxic tumor regression.J Biol Chem 287(4) 2907-14 1/20/2012
Khan M, Meduru S, Gogna R, Madan E, Citro L, Kuppusamy ML, Sayyid M, Mostafa M, Hamlin RL, Kuppusamy POxygen cycling in conjunction with stem cell transplantation induces NOS3 expression leading to attenuation of fibrosis and improved cardiac function.Cardiovasc Res 93(1) 89-99 1/1/2012
Ravi Y, Selvendiran K, Meduru S, Citro L, Naidu S, Khan M, Rivera BK, Sai-Sudhakar CB, Kuppusamy PDysregulation of PTEN in Cardiopulmonary Vascular Remodeling Induced by Pulmonary Hypertension.Cell Biochem Biophys in press 12/29/2011
Madan E, Gogna R, Bhatt M, Pati U, Kuppusamy P, Mahdi AARegulation of glucose metabolism by p53: emerging new roles for the tumor suppressor.Oncotarget 2(12) 948-57 12/1/2011
Naushad SM, Reddy CA, Rupasree Y, Pavani A, Digumarti RR, Gottumukkala SR, Kuppusamy P, Kutala VKCross-talk between one-carbon metabolism and xenobiotic metabolism: implications on oxidative DNA damage and susceptibility to breast cancer.Cell Biochem Biophys 61(3) 715-23 12/1/2011
Dayton A, Selvendiran K, Meduru S, Khan M, Kuppusamy M, Naidu S, Kalai T, Hideg K, Kuppusamy PAmelioration of doxorubicin-induced cardiotoxicity by an anticancer-antioxidant dual-function compound, HO-3867.J Pharmacol Exp Ther 339(2) 350-7 11/1/2011
Selvendiran K, Ahmed S, Dayton A, Kuppusamy ML, Rivera BK, Kálai T, Hideg K, Kuppusamy PHO-3867, a curcumin analog, sensitizes cisplatin-resistant ovarian carcinoma, leading to therapeutic synergy through STAT3 inhibition.Cancer Biol Ther 12(9) 837-45 11/1/2011
Kalai T, Kuppusamy LM, Balog M, Selvendrian K, Rivera B, Kuppusamy P, Hideg KSynthesis of N-substituted 3,5-bis(arylidene)-4-piperidones with high antitumor and antioxidant activity.J Med Chem 54(15) 5414-21 8/11/2011
Mundy-Bosse BL, Lesinski GB, Jaime-Ramirez AC, Benninger K, Khan M, Kuppusamy P, Guenterberg K, Kondadasula SV, Ray Chaudhury A, La Perle KM, Kreiner M, Young GS, Guttridge DC, Carson WEMyeloid-derived suppressor cell inhibition of the IFN response in tumor-bearing mice.Cancer Res 71(15) 5101-10 8/1/2011